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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
shares in Thousands, $ in Thousands
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Deficit [Member]
Total
Balance at Dec. 31, 2017 $ 116 $ 965,752 $ (32) $ (879,733) $ 86,103
Balance, shares at Dec. 31, 2017 116,277        
Balance at Mar. 31, 2018 $ 132 1,006,367 (38) (903,723) 102,738
Balance, shares at Mar. 31, 2018 131,872        
Balance at Dec. 31, 2017 $ 116 965,752 (32) (879,733) 86,103
Balance, shares at Dec. 31, 2017 116,277        
Net loss       (46,719) (46,719)
Other comprehensive income (loss)     16   16
ASC606 adoption effect       189 189
Issuance of common stock in conjunction with equity plans $ 2 2,515     2,517
Issuance of common stock in conjunction with equity plans, shares 1,236        
Issuance of common stock from ATM equity offering, net of issuance costs $ 14 32,848     32,862
Issuance of common stock from ATM equity offering, net of issuance costs, shares 14,375        
Stock-based compensation expense   10,506     10,506
Balance at Jun. 30, 2018 $ 132 1,011,621 (16) (926,263) 85,474
Balance, shares at Jun. 30, 2018 131,888        
Balance at Dec. 31, 2017 $ 116 965,752 (32) (879,733) 86,103
Balance, shares at Dec. 31, 2017 116,277        
Balance at Dec. 31, 2018 $ 150 1,096,053 (36) (982,106) $ 114,061
Balance, shares at Dec. 31, 2018 150,244       150,244
Balance at Mar. 31, 2018 $ 132 1,006,367 (38) (903,723) $ 102,738
Balance, shares at Mar. 31, 2018 131,872        
Net loss       (22,540) (22,540)
Other comprehensive income (loss)     22   22
Issuance of common stock in conjunction with equity plans   30     30
Issuance of common stock in conjunction with equity plans, shares 16        
Stock-based compensation expense   5,224     5,224
Balance at Jun. 30, 2018 $ 132 1,011,621 (16) (926,263) 85,474
Balance, shares at Jun. 30, 2018 131,888        
Balance at Dec. 31, 2018 $ 150 1,096,053 (36) (982,106) $ 114,061
Balance, shares at Dec. 31, 2018 150,244       150,244
Balance at Mar. 31, 2019 $ 153 1,107,121 6 (1,012,430) $ 94,850
Balance, shares at Mar. 31, 2019 152,672        
Balance at Dec. 31, 2018 $ 150 1,096,053 (36) (982,106) $ 114,061
Balance, shares at Dec. 31, 2018 150,244       150,244
Net loss       (54,920) $ (54,920)
Other comprehensive income (loss)     53   53
Issuance of common stock in conjunction with equity plans $ 3 8,087     8,090
Issuance of common stock in conjunction with equity plans, shares 2,715        
Stock-based compensation expense   8,470     8,470
Balance at Jun. 30, 2019 $ 153 1,112,610 17 (1,037,026) $ 75,754
Balance, shares at Jun. 30, 2019 152,959       152,959
Balance at Mar. 31, 2019 $ 153 1,107,121 6 (1,012,430) $ 94,850
Balance, shares at Mar. 31, 2019 152,672        
Net loss       (24,596) (24,596)
Other comprehensive income (loss)     11   11
Issuance of common stock in conjunction with equity plans   1,400     1,400
Issuance of common stock in conjunction with equity plans, shares 287        
Stock-based compensation expense   4,089     4,089
Balance at Jun. 30, 2019 $ 153 $ 1,112,610 $ 17 $ (1,037,026) $ 75,754
Balance, shares at Jun. 30, 2019 152,959       152,959