<SEC-DOCUMENT>0001299130-19-000035.txt : 20190520
<SEC-HEADER>0001299130-19-000035.hdr.sgml : 20190520
<ACCEPTANCE-DATETIME>20190520161629
ACCESSION NUMBER:		0001299130-19-000035
CONFORMED SUBMISSION TYPE:	SD
PUBLIC DOCUMENT COUNT:		2
<RULE>
<RULE-NAME>13p-1
<ITEM>
<ITEM-NUMBER>1.01
<ITEM-PERIOD>20181231
</ITEM>
</RULE>
FILED AS OF DATE:		20190520
DATE AS OF CHANGE:		20190520

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
		CENTRAL INDEX KEY:			0001299130
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				161590339
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SD
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34899
		FILM NUMBER:		19838949

	BUSINESS ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-521-8000

	MAIL ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PACIFIC BIOSCIENCES OF CALIFORNIA INC
		DATE OF NAME CHANGE:	20050829

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NANOFLUIDICS INC
		DATE OF NAME CHANGE:	20040729
</SEC-HEADER>
<DOCUMENT>
<TYPE>SD
<SEQUENCE>1
<FILENAME>pacb-20181231x8k.htm
<DESCRIPTION>FORM SD
<TEXT>
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			Form SD
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			<font style="display: inline;font-weight:bold;font-size:18pt;">UNITED STATES</font>
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			<font style="display: inline;font-weight:bold;font-size:18pt;">SECURITIES AND EXCHANGE COMMISSION</font>
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			<font style="display: inline;font-weight:bold;">Washington, DC 20549</font>
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			<font style="display: inline;font-weight:bold;font-size:18pt;">FORM SD</font>
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		<p style="margin:4.5pt 0pt 0pt;text-align:center;font-family:Times New Roman;font-size: 12pt">
			<font style="display: inline;font-weight:bold;">Specialized Disclosure Report</font>
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			<font style="display: inline;">&nbsp;</font>
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			<font style="display: inline;font-weight:bold;font-size:24pt;">Pacific Biosciences of California, Inc.</font>
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			<font style="display: inline;font-weight:bold;font-size:10pt;">(Exact name of registrant as specified in its charter)</font>
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						<font style="display: inline;font-weight:bold;font-size:10pt;">Delaware</font></p>
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						<font style="display: inline;font-weight:bold;font-size:10pt;">001-34899</font></p>
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						<font style="display: inline;font-weight:bold;font-size:10pt;">16-1590339</font></p>
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						<font style="display: inline;font-weight:bold;font-size:7.5pt;">(State or other jurisdiction</font></p>
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						<font style="display: inline;font-weight:bold;font-size:7.5pt;">of incorporation)</font></p>
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						<font style="display: inline;font-weight:bold;font-size:7.5pt;">(Commission</font></p>
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						<font style="display: inline;font-weight:bold;font-size:7.5pt;">File Number)</font></p>
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						<font style="display: inline;">&nbsp;</font></p>
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						<font style="display: inline;font-weight:bold;font-size:7.5pt;">(IRS Employer</font></p>
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						<font style="display: inline;font-weight:bold;font-size:7.5pt;">Identification No.)</font></p>
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		<p style="margin:9pt 0pt 0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">1305 O&#x2019;Brien Drive</font>
		</p>
		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">Menlo Park, California 94025</font>
		</p>
		<p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 7pt">
			<font style="display: inline;font-weight:bold;font-size:7.5pt;">(Address of principal executive offices, including zip code)</font>
		</p>
		<p style="margin:12pt 0pt 0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">Stephen M. Moore</font><br /><font style="display: inline;font-weight:bold;font-size:10pt;">Vice President, General Counsel and Corporate Secretary</font><br /><font style="display: inline;font-weight:bold;font-size:10pt;"></font><font style="display: inline;font-weight:bold;font-size:10pt;">(650) 521-8000</font>
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			<font style="display: inline;font-weight:bold;font-size:7.5pt;">(Name and telephone number, including area code, of the person to contact in connection with this report)</font>
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		<p style="margin:0pt;font-family:Times New Roman;font-size: 5pt">
			<font style="display: inline;">&nbsp;</font>
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		<p style="margin:0pt 227.4pt;border-bottom:1pt solid #000000 ;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;">&nbsp;</font>
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		<p style="margin:4.5pt 0pt 0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">Check the appropriate box to indicate the rule pursuant to which this form is being filed, and provide the period to which the information in this form applies:</font>
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		<p style="margin:4.5pt 0pt 0pt 18pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:9pt;">&#x2612;</font><font style="display: inline;font-size:9pt;"></font><font style="display: inline;font-size:10pt;">Rule 13p-1 under the Securities Exchange Act (17 CFR 240.13p-1) for the reporting period from January 1 to December 31, 201</font><font style="display: inline;font-size:10pt;">8</font><font style="display: inline;font-size:10pt;">.</font>
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			<font style="display: inline;">&nbsp;</font>
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			<font style="display: inline;">&nbsp;</font>
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			<font style="display: inline;font-weight:bold;font-family:Times New Roman;font-weight:bold;text-transform:uppercase;font-size:10pt;">Section 1.</font><font style="display: inline;font-weight:bold;font-family:Times New Roman;font-weight:bold;text-transform:uppercase;font-size:10pt;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;font-weight:bold;font-family:Times New Roman;font-weight:bold;text-transform:uppercase;font-size:10pt;">Conflict minerals disclsosure</font>
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		<p style="margin:4.5pt 0pt 0pt;text-indent:0pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">Item 1.01 Conflict Minerals Disclosure and Report</font>
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		<p style="margin:6pt 0pt 0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">A copy of&nbsp;Pacific Biosciences of California, Inc.&#x2019;s (the &#x201C;Company&#x2019;s&#x201D;)&nbsp;Conflict Minerals Report for the reporting period January 1, 201</font><font style="display: inline;font-size:10pt;">8</font><font style="display: inline;font-size:10pt;"> to December 31, 201</font><font style="display: inline;font-size:10pt;">8</font><font style="display: inline;font-size:10pt;"> is provided as Exhibit 1.01 hereto and is publicly available </font><font style="display: inline;font-size:10pt;">at&nbsp;</font><font style="display: inline;font-size:10pt;">www.pacb.com</font><font style="display: inline;font-size:10pt;">.&nbsp;The Company&#x2019;s</font><font style="display: inline;font-size:10pt;"> determination and related disclosures relating to materials that may&nbsp;come from&nbsp;the Democratic Republic of Congo, the Republic of Congo, the Central African Republic, South Sudan, Uganda, Rwanda, Burundi, Tanzania, Zambia or Angola or from&nbsp;recycled and scrap&nbsp;sources that are included in&nbsp;the Company&#x2019;s Conflict Minerals Report and incorporated by reference herein.</font>
		</p>
		<p style="margin:6pt 0pt 0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">&#xFEFF;</font>
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			<font style="display: inline;font-weight:bold;font-size:10pt;">Item 1.02 </font><font style="display: inline;font-weight:bold;font-size:10pt;">Exhibit</font>
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		<p style="margin:6pt 0pt 0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">In accordance with Rule 13p-1, and this Form SD, the Company is hereby filing its Conflict Minerals Report for the calendar year ended December 31, 201</font><font style="display: inline;font-size:10pt;">8</font><font style="display: inline;font-size:10pt;"> as Exhibit 1.01 to this report.</font>
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			<font style="display: inline;font-weight:bold;font-family:Times New Roman;font-weight:bold;text-transform:uppercase;font-size:10pt;">Section 2.</font><font style="display: inline;font-weight:bold;font-family:Times New Roman;font-weight:bold;text-transform:uppercase;font-size:10pt;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;font-weight:bold;font-family:Times New Roman;font-weight:bold;text-transform:uppercase;font-size:10pt;">Exhibits</font>
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		<p style="margin:6pt 0pt 0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">The following exhibits are filed as part of this report:</font>
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		<p style="margin:4.5pt 0pt 0pt;text-indent:0pt;border-bottom:1pt none #D9D9D9 ;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 10pt">
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			<font style="display: inline;font-weight:bold;font-size:10pt;">Item 2.01 Exhibits</font>
		</p>
		<p style="margin:6pt 0pt 0pt;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">Exhibit 1.01 &#x2014; 201</font><font style="display: inline;font-size:10pt;">8</font><font style="display: inline;font-size:10pt;"> Conflict Minerals Report of Pacific Biosciences of California, Inc. as required by Items 1.01 and 1.02 of this Form SD.</font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:11.25pt 0pt 0pt;text-align:center;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">SIGNATURE</font>
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			<font style="display: inline;font-size:10pt;">Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.</font>
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			<font style="display: inline;">&nbsp;</font>
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					<p style="margin:0pt;font-family:Times New Roman;height:1.00pt;overflow:hidden;font-size: 1pt">
						<font style="display: inline;font-size:1pt;">Susan </font></p>
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						&nbsp;</p>
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						&nbsp;</p>
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						&nbsp;</p>
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					<p style="margin:0pt 2.8pt 0pt 0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;font-size:10pt;">Pacific Biosciences of California, Inc.</font></p>
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						<font style="display: inline;font-size:10pt;">By:</font></p>
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						<font style="display: inline;">&nbsp;</font></p>
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						<font style="display: inline;font-size:10pt;">/s/ Susan K. Barnes</font><font style="display: inline;font-size:8pt;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</font></p>
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						<font style="display: inline;">&nbsp;</font></p>
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					<p style="margin:0pt 0.8pt 0pt 0pt;text-align:center;font-family:Times New Roman;font-size: 7pt">
						<font style="display: inline;font-weight:bold;font-size:7.5pt;">Susan K. Barnes</font></p>
					<p style="margin:0pt 0.8pt 0pt 0pt;text-align:center;font-family:Times New Roman;font-size: 7pt">
						<font style="display: inline;font-weight:bold;font-size:7.5pt;">Executive Vice President, Chief Financial Officer and Principal Accounting Officer</font></p>
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			<font style="display: inline;font-size:10pt;">Date: </font><font style="display: inline;font-size:10pt;">May</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">20</font><font style="display: inline;font-size:10pt;">, 201</font><font style="display: inline;font-size:10pt;">9</font>
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		<p><font size="1"> </font></p><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p>
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			<font style="display: inline;font-weight:bold;font-size:10pt;">EXHIBIT INDEX</font>
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			<font style="display: inline;font-weight:bold;font-size:10pt;">&#xFEFF;</font>
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						<font style="display: inline;font-size:1pt;">5</font></p>
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					<p style="margin:0pt;border-bottom:1pt solid #000000 ;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-weight:bold;font-size:10pt;">Exhibit No.</font></p>
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						<font style="display: inline;font-weight:bold;font-size:10pt;">Description</font></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<font style="display: inline;font-size:10pt;">&#xFEFF;</font><a href="pacb-20181231xex1_01.htm" style="-sec-extract:exhibit"><font style="display: inline;font-size:10pt;">1.01</font></a></p>
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					<p style="margin:0pt;font-family:Times New Roman;font-size: 10pt">
						<a href="pacb-20181231xex1_01.htm" style="-sec-extract:exhibit"><font style="display: inline;font-size:10pt;">2018 Conflict Minerals Report of Pacific Biosciences of California, Inc. as required by Items 1.01 and 1.02 of this Form SD.</font></a></p>
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<DOCUMENT>
<TYPE>EX-1.01
<SEQUENCE>2
<FILENAME>pacb-20181231xex1_01.htm
<DESCRIPTION>EXHIBIT 1.01
<TEXT>
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			Form SD - Exhibit 1.01
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		<p style="margin:0pt;text-align:right;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<a name="_GoBack"></a><font style="display: inline;font-weight:bold;font-size:10pt;">Exhibit 1.0</font><font style="display: inline;font-weight:bold;font-size:10pt;">1</font>
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			<font style="display: inline;">&#xFEFF;</font>
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		<p style="margin:0pt;text-align:center;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">Conflict Minerals Report of Pacific Biosciences of California, Inc. </font>
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		<p style="margin:0pt;text-align:center;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;">in Accordance with Rule 13p-1 under the Securities Exchange Act of 1934 </font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">This is the Conflict Minerals Report (&#x201C;CMR&#x201D;) of Pacific Biosciences of California, Inc. (&#x201C;PACB&#x201D;</font><font style="display: inline;font-size:10pt;"> or</font><font style="display: inline;font-size:10pt;"> the &#x201C;Company&#x201D;) for </font><font style="display: inline;font-size:10pt;">the reporting period January 1, </font><font style="display: inline;font-size:10pt;">2018</font><font style="display: inline;font-size:10pt;"> to December 31, </font><font style="display: inline;font-size:10pt;">2018</font><font style="display: inline;font-size:10pt;"> in accordance with Rule 13p-1 (&#x201C;Rule 13p-1&#x201D;) under the Securities Exchange Act of 1934, as amended (the &#x201C;1934 Act&#x201D;). </font><font style="display: inline;font-size:10pt;">Rule </font><font style="display: inline;font-size:10pt;">13p-1</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">requires disclosure of certain information when a company manufactures or contracts to manufacture products and the minerals specified in Rule </font><font style="display: inline;font-size:10pt;">13p-1</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">are necessary to the functionality or production of those products. The specified minerals referred to as &#x201C;</font><font style="display: inline;font-size:10pt;">C</font><font style="display: inline;font-size:10pt;">onflict </font><font style="display: inline;font-size:10pt;">M</font><font style="display: inline;font-size:10pt;">inerals&#x201D; are gold, columbite-tantalite (coltan), cassiterite and wolframite, including their derivatives which include tantalum, tin and tungsten</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">(collectively,</font><font style="display: inline;font-size:10pt;"> the</font><font style="display: inline;font-size:10pt;"> &#x201C;3TG</font><font style="display: inline;font-size:10pt;"> Minerals</font><font style="display: inline;font-size:10pt;">&#x201D;)</font><font style="display: inline;font-size:10pt;">. The &#x201C;Covered Countries&#x201D; for purposes of Rule</font><font style="display: inline;font-size:10pt;"> 13p-1</font><font style="display: inline;font-size:10pt;"> and this </font><font style="display: inline;font-size:10pt;">CMR</font><font style="display: inline;font-size:10pt;"> are the Democratic Republic of Congo</font><font style="display: inline;font-size:10pt;"> (&#x201C;DRC&#x201D;)</font><font style="display: inline;font-size:10pt;">, the Republic of Congo, the Central African Republic, South Sudan, Uganda, Rwanda, Burundi, Tanzania, Zambia and Angola.</font><font style="display: inline;font-size:10pt;"> &nbsp; &nbsp;</font><font style="display: inline;font-size:10pt;">Please refer to Rule 13p-1, Form SD and the 1934 Act Release No.&nbsp;34-67716 for definitions to the terms used in this </font><font style="display: inline;font-size:10pt;">CMR</font><font style="display: inline;font-size:10pt;">, unless otherwise defined herein. </font>
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			<font style="display: inline;font-weight:bold;font-size:10pt;text-decoration:underline;">Company Overview</font>
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		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;text-align:justify;text-justify:inter-ideograph;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">PACB designs, develops and manufactures sequencing systems to help scientists resolve genetically complex problems. Based on the Company&#x2019;s novel Single Molecule, Real-Time (SMRT</font><font style="display: inline;font-size:10pt;font-size:5pt;vertical-align:super;line-height:100%">&#xAE;</font><font style="display: inline;font-size:10pt;">) &nbsp;</font><font style="display: inline;font-size:10pt;">s</font><font style="display: inline;font-size:10pt;">equencing </font><font style="display: inline;font-size:10pt;">technology, its products enable: </font><font style="display: inline;font-style:italic;font-size:10pt;">de novo</font><font style="display: inline;font-size:10pt;"> genome assembly to finish genomes in order to more fully identify, annotate and decipher genomic structures; full-length transcript analysis to improve annotations in reference genomes, characterize alternatively spliced isoforms </font><font style="display: inline;font-size:10pt;">in important gene families, </font><font style="display: inline;font-size:10pt;">and find novel genes; targeted sequencing to more comprehensively characterize genetic variations; </font><font style="display: inline;color:#000000;font-size:10pt;">and </font><font style="display: inline;color:#000000;font-size:10pt;">real-time kinetic information for epigenome characterization</font><font style="display: inline;color:#000000;font-size:10pt;">.</font><font style="display: inline;color:#000000;font-size:10pt;"> The Company&#x2019;s technology </font><font style="display: inline;color:#000000;font-size:10pt;">provides</font><font style="display: inline;color:#000000;font-size:10pt;"> high accuracy</font><font style="display: inline;color:#000000;font-size:10pt;">, ultra-long reads, uniform coverage and the ability to simultaneously detect epigenetic changes</font><font style="display: inline;color:#000000;font-size:10pt;">. &nbsp;</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">PacBio&#xAE; sequencing systems, including consumables and software, provide a simple and fast end-to-end workflow for SMRT sequencing.</font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">PACB supports the goal of avoiding the use of &#x201C;conflict minerals&#x201D; mined from troubled regions in the </font><font style="display: inline;font-size:10pt;">Covered C</font><font style="display: inline;font-size:10pt;">ountries</font><font style="display: inline;font-size:10pt;">,</font><font style="display: inline;font-size:10pt;"> the exploitation and trade of which may help finance armed conflict or benefit armed groups</font><font style="display: inline;font-size:10pt;">. &nbsp;</font><font style="display: inline;font-size:10pt;">PACB conducted an analysis of its products and </font><font style="display: inline;font-size:10pt;">determined that certain </font><font style="display: inline;font-size:10pt;">3TG</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">M</font><font style="display: inline;font-size:10pt;">inerals</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">are necessary to the functionality or production of</font><font style="display: inline;font-size:10pt;"> its PacBio</font><font style="display: inline;font-size:10pt;font-size:5pt;vertical-align:super;line-height:100%">&#xAE;</font><font style="display: inline;font-size:10pt;"> Sequel</font><font style="display: inline;font-size:10pt;font-size:5pt;vertical-align:super;line-height:100%">TM</font><font style="display: inline;font-weight:bold;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">instrument and </font><font style="display: inline;font-size:10pt;">related consumables</font><font style="display: inline;font-size:10pt;">.</font><font style="display: inline;font-size:10pt;"> &nbsp; &nbsp;</font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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			<font style="display: inline;font-weight:bold;font-size:10pt;text-decoration:underline;">Reasonable country of origin inquiry</font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">PACB</font><font style="display: inline;font-size:10pt;"> has conducted a reasonable country of origin inquiry (&#x201C;RCOI&#x201D;) reasonably designed to determine if </font><font style="display: inline;font-size:10pt;">3TG </font><font style="display: inline;font-size:10pt;">Minerals </font><font style="display: inline;font-size:10pt;">used in its products </font><font style="display: inline;font-size:10pt;">originated in the Covered Countries. </font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">The Company&#x2019;s RCOI</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">process began with an evaluation of its suppliers that provided materials, components or products that became part of products PACB manufactured or contracted to manufacture in </font><font style="display: inline;font-size:10pt;">2018</font><font style="display: inline;font-size:10pt;">, which </font><font style="display: inline;font-size:10pt;">the Company</font><font style="display: inline;font-size:10pt;"> knew contained or were likely to contain </font><font style="display: inline;font-size:10pt;">3TG Minerals</font><font style="display: inline;font-size:10pt;">. This evaluation consisted of examining internal records such as bills of materials </font><font style="display: inline;font-size:10pt;">and</font><font style="display: inline;font-size:10pt;"> other product specifications</font><font style="display: inline;font-size:10pt;">,</font><font style="display: inline;font-size:10pt;"> and performing a qualitative review of purchasing records and/or information provided by the supplier</font><font style="display: inline;font-size:10pt;">s</font><font style="display: inline;font-size:10pt;">. Based on </font><font style="display: inline;font-size:10pt;">its</font><font style="display: inline;font-size:10pt;"> evaluation, </font><font style="display: inline;font-size:10pt;">the Company then</font><font style="display: inline;font-size:10pt;"> surveyed the suppliers of those materials, components or products which it concluded contained or were likely to contain </font><font style="display: inline;font-size:10pt;">3TG Minerals</font><font style="display: inline;font-size:10pt;">. The suppliers were asked to report on the presence of any </font><font style="display: inline;font-size:10pt;">3TG Minerals</font><font style="display: inline;font-size:10pt;"> in the goods sold to PACB. In cases where PACB confirmed that </font><font style="display: inline;font-size:10pt;">3TG Minerals</font><font style="display: inline;font-size:10pt;"> were present, it asked the applicable supplier to submit information to PACB about the country of origin of the </font><font style="display: inline;font-size:10pt;">3TG Minerals</font><font style="display: inline;font-size:10pt;">.</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-style:italic;font-size:10pt;background-color:yellow;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;text-decoration:underline;">Due Diligence</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;text-decoration:underline;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">PACB performed due diligence procedures to determine the </font><font style="display: inline;font-size:10pt;">Conflict Minerals</font><font style="display: inline;font-size:10pt;"> status of the </font><font style="display: inline;font-size:10pt;">3TG Minerals</font><font style="display: inline;font-size:10pt;"> used in its products. In conducting its due diligence, PACB implemented the Organization for Economic Co-operation and Development (&#x201C;OECD&#x201D;) Due Diligence Guidance for Responsible Supply Chains of Minerals from Conflict-Affected and High-Risk Areas (the &#x201C;OECD </font><font style="display: inline;font-size:10pt;">Guidance</font><font style="display: inline;font-size:10pt;">&#x201D;), an internationally recognized due diligence </font>
		</p>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;text-align:center;line-height:100%;font-family:Times New Roman;font-size: 12pt">

			<font style="display: inline;"></font><font style="display: inline;">1</font><font style="display: inline;"></font>

		</p>

		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 12pt">

			&nbsp;

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt"><font style="display: inline;font-size:10pt;">framework</font><font style="display: inline;font-size:10pt;">.&nbsp;&nbsp;The Company designed its due diligence process, management and measures within the OECD </font><font style="display: inline;font-size:10pt;">Guidance</font><font style="display: inline;font-size:10pt;"> for a company downstream in the supply chain.</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;text-indent:18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">As a company </font><font style="display: inline;font-size:10pt;">that supplies sequencing systems</font><font style="display: inline;font-size:10pt;">, PACB is several levels removed from the actual mining of 3TG</font><font style="display: inline;font-size:10pt;"> Minerals</font><font style="display: inline;font-size:10pt;">. PACB does not make purchases of raw ore or unrefined 3TG </font><font style="display: inline;font-size:10pt;">Minerals </font><font style="display: inline;font-size:10pt;">and makes no purchases of 3TG </font><font style="display: inline;font-size:10pt;">Minerals </font><font style="display: inline;font-size:10pt;">directly from the</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">Covered Countries. </font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;text-indent:18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">The following is a summary of the due diligence actions that PACB has taken with regard</font><font style="display: inline;font-size:10pt;">s</font><font style="display: inline;font-size:10pt;"> to the reporting period for which this CMR is submitted:</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:18pt;"><p style="width:18pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-weight:bold;border-bottom:1pt none #D9D9D9;line-height:100%;font-family:Times New Roman;font-size:10pt;;"> 1)</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">Establish strong company management systems</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 36pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-top:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;border-top:1pt none #D9D9D9;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-top:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company e</font><font style="display: inline;font-size:10pt;color:#000000;">stablished an internal management team and coordinator to ensure compliance with respect to the reporting requirements relating to </font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;">. PACB&#x2019;s internal management team consists of, or works with, representatives from supply chain and procurement, engineering, legal and finance.</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company d</font><font style="display: inline;font-size:10pt;color:#000000;">efined the scope of </font><font style="display: inline;font-size:10pt;color:#000000;">it</font><font style="display: inline;font-size:10pt;color:#000000;">s &nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> due diligence by identifying and reaching out to current suppliers that provide components or engage in manufacturing activities that are likely to contain 3TG</font><font style="display: inline;font-size:10pt;color:#000000;"> Minerals</font><font style="display: inline;font-size:10pt;color:#000000;">.</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company then d</font><font style="display: inline;font-size:10pt;color:#000000;">etermined data gathering and assessment procedures to understand the scope of PACB&#x2019;s supply chain inquiry.</font></p></td></tr></table></div>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:18pt;"><p style="width:18pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-weight:bold;line-height:100%;font-family:Times New Roman;font-size:10pt;;"> 2)</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">Identify and assess risks in the supply chain</font></p></td></tr></table></div>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;border-bottom:1pt none #D9D9D9;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company a</font><font style="display: inline;font-size:10pt;color:#000000;">dopted the standard Conflict Minerals Reporting Template established by </font><font style="display: inline;font-size:10pt;color:#000000;">the </font><font style="display: inline;font-size:10pt;color:#000000;">Responsible Business Alliance</font><font style="display: inline;font-size:10pt;color:#000000;"> (&#x201C;</font><font style="display: inline;font-size:10pt;color:#000000;">RBA</font><font style="display: inline;font-size:10pt;color:#000000;">&#x201D;) and</font><font style="display: inline;font-size:10pt;color:#000000;"> Global e-Sustainability Initiative (&#x201C;GeSI&#x201D;) for data collection and verification. PACB requested product-level information from its direct suppliers on the parts and products </font><font style="display: inline;font-size:10pt;color:#000000;">that </font><font style="display: inline;font-size:10pt;color:#000000;">it purchased from them.</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 54pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-top:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;border-top:1pt none #D9D9D9;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-top:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company increased </font><font style="display: inline;font-size:10pt;color:#000000;">awareness of PACB&#x2019;s </font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> program </font><font style="display: inline;font-size:10pt;color:#000000;">by </font><font style="display: inline;font-size:10pt;color:#000000;">provid</font><font style="display: inline;font-size:10pt;color:#000000;">ing</font><font style="display: inline;font-size:10pt;color:#000000;"> suppliers with background materials describing the </font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> rule</font><font style="display: inline;font-size:10pt;color:#000000;">s</font><font style="display: inline;font-size:10pt;color:#000000;">, leading industry initiatives, </font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> tracing, reporting requirements, and other guidelines and resources relating to </font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;">. &nbsp;</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 18pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company </font><font style="display: inline;font-size:10pt;color:#000000;">r</font><font style="display: inline;font-size:10pt;color:#000000;">elied on these supplier&#x2019;s responses to provide PACB with information about the source of </font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> contained in the components supplied to PACB. PACB&#x2019;s direct suppliers of</font><font style="display: inline;font-size:10pt;color:#000000;"> components that contain</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> are similarly reliant upon information provided to them by their respective suppliers.</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company r</font><font style="display: inline;font-size:10pt;color:#000000;">eviewed and evaluated supplier responses for consistency and completeness </font><font style="display: inline;font-size:10pt;color:#000000;">and </font><font style="display: inline;font-size:10pt;color:#000000;">for information regarding </font><font style="display: inline;font-size:10pt;color:#000000;">the origin of those materials. </font></p></td></tr></table></div>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:18pt;"><p style="width:18pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-weight:bold;border-bottom:1pt none #D9D9D9;line-height:100%;font-family:Times New Roman;font-size:10pt;;"> 3)</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">Design and implement a strategy to respond to identified risks</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 36pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;border-top:1pt none #D9D9D9;border-bottom:1pt none #D9D9D9;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company reported t</font><font style="display: inline;font-size:10pt;color:#000000;">he status and findings of PACB&#x2019;s RCOI and due diligence efforts to </font><font style="display: inline;font-size:10pt;color:#000000;">its </font><font style="display: inline;font-size:10pt;color:#000000;">senior management. </font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 54pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-top:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-family:Symbol;border-top:1pt none #D9D9D9;line-height:100%;font-size:10pt;;"> &#xB7;</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-top:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-size:10pt;color:#000000;">The</font><font style="display: inline;font-size:10pt;color:#000000;"> Company </font><font style="display: inline;font-size:10pt;color:#000000;">followed a risk mitigation plan that is consistent with its </font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> approach: if a smelter or refiner in the supply chain w</font><font style="display: inline;font-size:10pt;color:#000000;">as</font><font style="display: inline;font-size:10pt;color:#000000;"> known to be sourcing </font><font style="display: inline;font-size:10pt;color:#000000;">Conflict Minerals</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">from a mine within a Covered Country which directly or indirectly finances or benefits armed groups, PACB would consider all available options, including, but not limited to, </font><font style="display: inline;font-size:10pt;color:#000000;">requesting</font><font style="display: inline;font-size:10pt;color:#000000;"> its suppliers to </font><font style="display: inline;font-size:10pt;color:#000000;">mak</font><font style="display: inline;font-size:10pt;color:#000000;">e</font><font style="display: inline;font-size:10pt;color:#000000;"> changes to its sourcing of those items</font><font style="display: inline;font-size:10pt;color:#000000;"> or changing suppliers</font><font style="display: inline;font-size:10pt;color:#000000;">.</font></p></td></tr></table></div>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">&#xFEFF;</font>
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		<p style="margin:0pt;text-align:center;line-height:100%;font-family:Times New Roman;font-size: 12pt">

			<font style="display: inline;"></font><font style="display: inline;">2</font><font style="display: inline;"></font>

		</p>

		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 12pt">

			&nbsp;

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p>
		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:18pt;"><p style="width:18pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-weight:bold;line-height:100%;font-family:Times New Roman;font-size:10pt;;"> 4)</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">Carry out i</font><font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">ndependent third-party audit</font><font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;"> of supply chain due diligence</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
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		<p style="margin:0pt 0pt 0pt 18pt;text-indent:18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company </font><font style="display: inline;font-size:10pt;color:#000000;">uses resources from the OECD and </font><font style="display: inline;font-size:10pt;color:#000000;">from the </font><font style="display: inline;font-size:10pt;color:#000000;">Responsible Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> Initiative (&#x201C;</font><font style="display: inline;font-size:10pt;color:#000000;">RMI</font><font style="display: inline;font-size:10pt;color:#000000;">&#x201D;) of</font><font style="display: inline;font-size:10pt;color:#000000;"> the </font><font style="display: inline;font-size:10pt;color:#000000;">RBA </font><font style="display: inline;font-size:10pt;color:#000000;">and GeSI, including </font><font style="display: inline;font-size:10pt;color:#000000;">RMI&#x2019;s </font><font style="display: inline;font-size:10pt;color:#000000;">conflict-free smelter lists. The </font><font style="display: inline;font-size:10pt;color:#000000;">RMI </font><font style="display: inline;font-size:10pt;color:#000000;">is a global leader for the responsible sourcing of minerals and provides information on conflict-free smelters and refiners, common tools to gather sourcing information, and forums for exchanging best practices on addressing Conflicts Minerals. Since PACB is a downstream company, the Company relied on cross-industry initiatives such as a &#x201C;conflict-free&#x201D; designation from the Conflict-Free Smelter Program led by the </font><font style="display: inline;font-size:10pt;color:#000000;">RMI </font><font style="display: inline;font-size:10pt;color:#000000;">in its due diligence efforts.&nbsp; </font>
		</p>
		<p style="margin:0pt 0pt 0pt 18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
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		<div style="width:100%"><table style="width:100%; table-layout: fixed;" cellpadding="0" cellspacing="0"><tr><td style="width:18pt;"><p style="width:18pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt;">
			<p style="border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
				<font style="margin:0pt;font-weight:bold;border-bottom:1pt none #D9D9D9;line-height:100%;font-family:Times New Roman;font-size:10pt;;"> 5)</font>
			</p>
		</td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top">
			<p style="border-bottom:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt;margin:0pt;">
			<font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">Report </font><font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">annually </font><font style="display: inline;font-weight:bold;font-size:10pt;color:#000000;">on supply chain due diligence</font></p></td></tr></table></div>
		<p style="margin:0pt 0pt 0pt 36pt;border-top:1pt none #D9D9D9 ;line-height:100%;font-family:Times New Roman;font-size: 10pt">
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		<p style="margin:0pt 0pt 0pt 18pt;text-indent:18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">The Company</font><font style="display: inline;font-size:10pt;color:#000000;"> plans to continue to report annually to the SEC by filing a Form SD and Conflict Minerals Report as required by applicable law.</font>
		</p>
		<p style="margin:0pt 0pt 0pt 18pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
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			<font style="display: inline;font-weight:bold;font-size:10pt;text-decoration:underline;color:#000000;">Findings and Conclusion</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">PACB sent out surveys to the </font><font style="display: inline;font-size:10pt;color:#000000;">38</font><font style="display: inline;font-size:10pt;color:#000000;"> suppliers identified in its due diligence efforts and received responses from </font><font style="display: inline;font-size:10pt;color:#000000;">3</font><font style="display: inline;font-size:10pt;color:#000000;">4</font><font style="display: inline;font-size:10pt;color:#000000;"> suppliers, providing a</font><font style="display: inline;font-size:10pt;color:#000000;">n</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">8</font><font style="display: inline;font-size:10pt;color:#000000;">9</font><font style="display: inline;font-size:10pt;color:#000000;">%</font><font style="display: inline;font-size:10pt;color:#000000;"> response rate. Consistent with the prior year, suppliers and manufacturers generally provided facility information at the &#x201C;Company Level,&#x201D; which represents the suppliers&#x2019; and manufacturers&#x2019; entire product lines, and generally did not limit their responses to facility information for covered minerals in products they specifically supply to PACB. In </font><font style="display: inline;font-size:10pt;color:#000000;">2018</font><font style="display: inline;font-size:10pt;color:#000000;">, &nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">3</font><font style="display: inline;font-size:10pt;color:#000000;"> suppliers provided responses specific to PACB products (&#x201C;Product Level&#x201D;). </font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;background-color:yellow;color:#000000;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">Out of the </font><font style="display: inline;font-size:10pt;color:#000000;">3</font><font style="display: inline;font-size:10pt;color:#000000;">4</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">responses received, </font><font style="display: inline;font-size:10pt;color:#000000;">3</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">stated that their products do not contain </font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;">, &nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">6</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">stated that at least some of their </font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> were sourced from Covered Countries and </font><font style="display: inline;font-size:10pt;color:#000000;">25</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">stated that they were uncertain as to the origin of the </font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> in their products or did not provide sufficient information to adequately determine the source.&nbsp;&nbsp;Of the </font><font style="display: inline;font-size:10pt;color:#000000;">6</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">suppliers that stated that at least some of their </font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> were sourced from Covered Countries, </font><font style="display: inline;font-size:10pt;color:#000000;">all 6</font><font style="display: inline;font-size:10pt;color:#000000;"> noted that all of their products were from sources certified as being conflict-free, actively obtaining conflict-free certification, or had complete control from mine to production.&nbsp;&nbsp;The remaining sources were uncertified or had an unknown certification status.&nbsp; </font><font style="display: inline;font-size:10pt;color:#000000;">However, PACB has not identified any known instances in which any </font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> were sourced directly or indirectly from armed groups of the conflict regions of the Covered Countries.</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
		</p>
		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">Of the </font><font style="display: inline;font-size:10pt;color:#000000;">31</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font><font style="display: inline;font-size:10pt;color:#000000;">suppliers whose responses indicated that their products may contain 3TG</font><font style="display: inline;font-size:10pt;color:#000000;"> Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> sourced from the Covered Countries, all but </font><font style="display: inline;font-size:10pt;color:#000000;">3</font><font style="display: inline;font-size:10pt;color:#000000;"> of those suppliers responded at the Company Level. As a result, many of those smelters identified by PACB&#x2019;s suppliers in Company Level declarations may not actually be involved in the products supplied to PACB. </font><font style="display: inline;font-size:10pt;color:#000000;">For the </font><font style="display: inline;font-size:10pt;color:#000000;">3</font><font style="display: inline;font-size:10pt;color:#000000;"> suppliers that indicated that their products may contain 3TG sourced from the Covered Countries that responded at the Product Level, </font><font style="display: inline;font-size:10pt;color:#000000;">all 3</font><font style="display: inline;font-size:10pt;color:#000000;"> noted that </font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> sourced from Covered Countries were from sources certified as being conflict-free, actively obtaining conflict-free certification, or had complete control from mine to production</font><font style="display: inline;font-size:10pt;color:#000000;">.</font><font style="display: inline;font-size:10pt;color:#000000;"> &nbsp; &nbsp;</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">Based on the representations made by its suppliers, PACB does not have sufficient information to determine whether its supply chain is &#x201C;DRC conflict-free&#x201D; for the calendar year </font><font style="display: inline;font-size:10pt;color:#000000;">2018</font><font style="display: inline;font-size:10pt;color:#000000;">. PACB has been unable to determine the origin of all 3TG</font><font style="display: inline;font-size:10pt;color:#000000;"> Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> used in </font><font style="display: inline;font-size:10pt;color:#000000;">certain integrated circuits and other components used in the manufacturing of its instruments and related consumables. This was due to a lack of information from its suppliers to conclude whether the </font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> originated in the Covered Countries and, if so, whether the </font><font style="display: inline;font-size:10pt;color:#000000;">3TG Minerals</font><font style="display: inline;font-size:10pt;color:#000000;"> were from recycle or scrap sources, were DRC conflict-free, or have not been found to be DRC conflict-free.</font><font style="display: inline;font-size:10pt;color:#000000;">&nbsp;</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
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		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;text-decoration:underline;color:#000000;">Future Steps</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;color:#000000;">PACB is continuing to develop methods, implement tools and adopt procedures that are designed to be both auditable and in accordance with the OECD </font><font style="display: inline;font-size:10pt;color:#000000;">Guidance</font><font style="display: inline;font-size:10pt;color:#000000;">. In the next compliance period, PACB intends to continue to develop its processes in working with its suppliers to provide accurate and complete information regarding conflict mineral sourcing.</font>
		</p>
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		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">

		</p>
		<p><font size="1"> </font></p><div style="width:100%">

		<p style="margin:0pt;text-align:center;line-height:100%;font-family:Times New Roman;font-size: 12pt">

			<font style="display: inline;"></font><font style="display: inline;">3</font><font style="display: inline;"></font>

		</p>

		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 12pt">

			&nbsp;

		</p>

</div><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;;font-size: 10pt"><font style="display: inline;font-weight:bold;font-size:10pt;text-decoration:underline;">Additional Risk Factors and Considerations</font>
		</p>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">This CMR contains forward looking statements relating to actions that PACB may take in the future. Such statements are based on the current expectations of PACB management and are neither promises nor guarantees of future performance of the actions. Subsequent events and developments may cause management&#x2019;s views to change. While PACB may elect to update these forward-looking statements at some point in the future, it specifically disclaims any obligation to do so. These forward-looking statements should not be relied upon as representing the Company&#x2019;s views as of any date subsequent to the date of this report.</font>
		</p>
		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">The statements above are based on the due diligence performed in good faith by PACB. The statements are all based on information available at the time, and many factors can introduce errors impacting </font><font style="display: inline;font-size:10pt;">or otherwise affect</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">PACB&#x2019;s </font><font style="display: inline;font-size:10pt;">Conflict Minerals</font><font style="display: inline;font-size:10pt;"> status. Some factors could include but are not limited to unavailable supplier data, incomplete supplier data, incomplete smelter data, errors or omissions in supplier or smelter responses, </font><font style="display: inline;font-size:10pt;">all instances of </font><font style="display: inline;font-size:10pt;">Conflict Minerals</font><font style="display: inline;font-size:10pt;"> necessary to the functionality or manufacturing of </font><font style="display: inline;font-size:10pt;">PACB</font><font style="display: inline;font-size:10pt;">&#x2019;s products possibly not yet having been identified, </font><font style="display: inline;font-size:10pt;">public information not discovered during a reasonable search, errors in public data, language barriers and translation,</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">Covered Countries sourced materials being declared secondary materials, </font><font style="display: inline;font-size:10pt;">companies going out of business, s</font><font style="display: inline;font-size:10pt;">muggling of </font><font style="display: inline;font-size:10pt;">Conflict Minerals</font><font style="display: inline;font-size:10pt;"> from the Covered Countries to countri</font><font style="display: inline;font-size:10pt;">es beyond the Covered Countries,</font><font style="display: inline;font-size:10pt;">&nbsp;</font><font style="display: inline;font-size:10pt;">and suppliers or smelter operators who are unfamiliar with the </font><font style="display: inline;font-size:10pt;">Conflict Minerals</font><font style="display: inline;font-size:10pt;"> rules and protocols for responding to requests for information about </font><font style="display: inline;font-size:10pt;">Conflict Minerals</font><font style="display: inline;font-size:10pt;">.&nbsp; </font>
		</p>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">Suppliers and manufacturers generally provided facility information at the Company Level, representing the suppliers&#x2019; and manufacturers&#x2019; entire product lines, and generally did not limit their responses to facility information for covered minerals in products they specifically supply to PACB.&nbsp; </font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-weight:bold;font-size:10pt;text-decoration:underline;">Independent Private Sector Audit</font>
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		<p style="margin:0pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:0pt;text-indent:36pt;line-height:100%;font-family:Times New Roman;font-size: 10pt">
			<font style="display: inline;font-size:10pt;">This CMR has not been subject to an independent private sector audit as allowed under Rule 13p-1.</font>
		</p>
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			<font style="display: inline;">&nbsp;</font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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			<font style="display: inline;font-size:10pt;">&#xFEFF;</font>
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		<p style="margin:0pt;text-align:center;line-height:100%;font-family:Times New Roman;font-size: 12pt">

			<font style="display: inline;"></font><font style="display: inline;">4</font><font style="display: inline;"></font>

		</p>

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			&nbsp;

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