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Income Taxes (Reconciliation of Deferred Tax Assets and Liabilities) (Details) - USD ($) $ in Thousands | Dec. 31, 2019 | Dec. 31, 2018
--- | --- | ---
Deferred tax assets: |  |
Net operating loss carryforwards | $ 226,911 | $ 212,424
Research and development credits | 45,853 | 42,635
Accruals and reserves | 8,024 | 4,774
Stock-based compensation | 16,219 | 14,582
Deferred rent |  | 3,315
ASC842 Operating lease liability | 10,837 |
Total deferred tax assets | 307,844 | 277,730
Less: Valuation allowance | (298,658) | (275,540)
Total deferred tax assets: | 9,186 | 2,190
Fixed assets | (1,425) | (2,190)
ASC842 Operating Lease right-of-use assets | (7,761) |
Total deferred tax liabilities | (9,186) | (2,190)
Net deferred tax assets |  |

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