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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Revenue:      
Revenue $ 90,891 $ 78,626 $ 93,468
Cost of Revenue:      
Cost of revenue 56,315 53,530 58,809
Gross profit 34,576 25,096 34,659
Operating Expense:      
Research and development 59,630 62,594 65,324
Sales, general and administrative 75,491 63,489 59,119
Total operating expense 135,121 126,083 124,443
Operating loss (100,545) (100,987) (89,784)
Gain from Continuation Advances from Illumina 18,000    
Interest expense (2,611) (2,423) (2,921)
Other income, net 1,022 848 516
Net loss (84,134) (102,562) (92,189)
Other comprehensive loss:      
Unrealized gain (loss) on investments 41 (4) (37)
Comprehensive loss $ (84,093) $ (102,566) $ (92,226)
Net loss per share:      
Basic and diluted net loss per share $ (0.55) $ (0.76) $ (0.87)
Shares used in computing basic and diluted net loss per share 152,527,000 135,094,000 105,682,000
Product [Member]      
Revenue:      
Revenue $ 77,742 $ 66,355 $ 80,030
Cost of Revenue:      
Cost of revenue 44,771 42,053 42,900
Service and Other [Member]      
Revenue:      
Revenue 13,149 12,271 13,438
Cost of Revenue:      
Cost of revenue $ 11,544 $ 11,477 $ 15,909