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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2020
Mar. 31, 2020
Dec. 31, 2019
Jun. 30, 2019
Jun. 30, 2020
Jun. 30, 2019
Dec. 31, 2019
Cash flows from operating activities              
Net loss $ (23,086)     $ (24,596) $ (21,824) $ (54,920)  
Adjustments to reconcile net loss to net cash used in operating activities              
Gain from Continuation Advances   $ (34,000)     (34,000)   $ (18,000)
Depreciation         3,246 3,586  
Amortization of operating lease right-of-use assets         1,392 1,289  
Amortization of debt discount and financing costs         129 574  
Gain on derivative           (16)  
Stock-based compensation         7,266 8,470  
Amortization (accretion) from investment premium (discount)         (177) (677)  
Changes in assets and liabilities              
Accounts receivable         3,888 (3,528)  
Inventory         (3,822) (40)  
Prepaid expenses and other assets         524 388  
Accounts payable         (1,039) 685  
Accrued expenses         (1,039) 3,198  
Deferred revenue         (1,098) 734  
Operating lease liabilities         (1,835) (1,677)  
Other liabilities         1,963 (938)  
Deferred gain from Reverse Termination fee         98,000    
Net cash provided by (used in) operating activities         51,574 (42,872)  
Cash flows from investing activities              
Purchase of property and equipment         (436) (1,866)  
Purchase of investments         (119,200) (36,748)  
Maturities of investments         62,450 84,410  
Net cash provided by (used in) investing activities         (57,186) 45,796  
Cash flows from financing activities              
Continuation Advances   34,000 $ 18,000   34,000    
Notes payable principal payoff         (16,000)    
Proceeds from issuance of common stock from equity plans         827 8,090  
Net cash provided by financing activities         18,827 8,090  
Net increase in cash and cash equivalents and restricted cash         13,215 11,014  
Cash and cash equivalents and restricted cash at beginning of period   $ 33,627     33,627 23,344 23,344
Cash and cash equivalents and restricted cash at end of period 46,842   33,627 34,358 46,842 34,358 33,627
Cash and cash equivalents at end of period 43,342   $ 29,627 30,358 43,342 30,358 $ 29,627
Restricted cash at end of period $ 3,500     $ 4,000 3,500 4,000  
Supplemental disclosure of cash flow information              
Inventory transferred to property and equipment         $ 366 $ 1,427