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Condensed Consolidated Statements of Stockholders' Equity - USD ($)
shares in Thousands, $ in Thousands
Common Stock [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Deficit [Member]
Revision of Prior Period, Accounting Standards Update, Adjustment [Member]
Accumulated Deficit [Member]
Revision of Prior Period, Accounting Standards Update, Adjustment [Member]
Total
Balance at Dec. 31, 2018 $ 150 $ 1,096,053 $ (36)   $ (982,106)   $ 114,061
Balance, shares at Dec. 31, 2018 150,244            
Net loss         (84,043)   (84,043)
Other comprehensive income (loss)     47       47
Issuance of common stock in conjunction with equity plans $ 3 8,414         8,417
Issuance of common stock in conjunction with equity plans, shares 2,787            
Stock-based compensation expense   12,532         12,532
Balance at Sep. 30, 2019 $ 153 1,116,999 11   (1,066,149)   51,014
Balance, shares at Sep. 30, 2019 153,031            
Balance at Jun. 30, 2019 $ 153 1,112,610 17   (1,037,026)   75,754
Balance, shares at Jun. 30, 2019 152,959            
Net loss         (29,123)   (29,123)
Other comprehensive income (loss)     (6)       (6)
Issuance of common stock in conjunction with equity plans   327         327
Issuance of common stock in conjunction with equity plans, shares 72            
Stock-based compensation expense   4,062         4,062
Balance at Sep. 30, 2019 $ 153 1,116,999 11   (1,066,149)   51,014
Balance, shares at Sep. 30, 2019 153,031            
Balance at Dec. 31, 2019 $ 153 1,120,999 5 $ (32) (1,066,240) $ (32) $ 54,917
Balance, shares at Dec. 31, 2019 153,119           153,119
Net loss         (45,532)   $ (45,532)
Other comprehensive income (loss)     113       113
Issuance of common stock in conjunction with equity plans $ 4 14,170         14,174
Issuance of common stock in conjunction with equity plans, shares 4,473            
Issuance of common stock from Underwritten Public Equity Offering, net of issuance costs $ 23 93,575         93,598
Issuance of common stock from Underwritten Public Equity Offering, net of issuance costs, shares 22,345            
Stock-based compensation expense   12,258         12,258
Balance at Sep. 30, 2020 $ 180 1,241,002 118   (1,111,804)   $ 129,496
Balance, shares at Sep. 30, 2020 179,937           179,937
Balance at Jun. 30, 2020 $ 154 1,129,091 243   (1,088,096)   $ 41,392
Balance, shares at Jun. 30, 2020 154,318            
Net loss         (23,708)   (23,708)
Other comprehensive income (loss)     (125)       (125)
Issuance of common stock in conjunction with equity plans $ 3 13,344         13,347
Issuance of common stock in conjunction with equity plans, shares 3,274            
Issuance of common stock from Underwritten Public Equity Offering, net of issuance costs $ 23 93,575         93,598
Issuance of common stock from Underwritten Public Equity Offering, net of issuance costs, shares 22,345            
Stock-based compensation expense   4,992         4,992
Balance at Sep. 30, 2020 $ 180 $ 1,241,002 $ 118   $ (1,111,804)   $ 129,496
Balance, shares at Sep. 30, 2020 179,937           179,937