<SEC-DOCUMENT>0001299130-20-000106.txt : 20200811
<SEC-HEADER>0001299130-20-000106.hdr.sgml : 20200811
<ACCEPTANCE-DATETIME>20200710142238
<PRIVATE-TO-PUBLIC>
ACCESSION NUMBER:		0001299130-20-000106
CONFORMED SUBMISSION TYPE:	CORRESP
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20200710

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
		CENTRAL INDEX KEY:			0001299130
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				161590339
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		CORRESP

	BUSINESS ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-521-8000

	MAIL ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PACIFIC BIOSCIENCES OF CALIFORNIA INC
		DATE OF NAME CHANGE:	20050829

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NANOFLUIDICS INC
		DATE OF NAME CHANGE:	20040729
</SEC-HEADER>
<DOCUMENT>
<TYPE>CORRESP
<SEQUENCE>1
<FILENAME>filename1.htm
<TEXT>
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		<title>
			Company Acceleration Request
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			<font style="display: inline;"><img src="pacb-20200710correspg001.jpg" style="width: 3.171528in; height: 0.7423611in" alt="Picture 2"></font>

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			<font style="display: inline;">July</font><font style="display: inline;">&nbsp;</font><font style="display: inline;">10</font><font style="display: inline;">, 2020</font>
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			<font style="display: inline;font-weight:bold;font-style:italic;text-decoration:underline;">V</font><font style="display: inline;font-weight:bold;font-style:italic;text-decoration:underline;">ia</font><font style="display: inline;font-weight:bold;font-style:italic;text-decoration:underline;"> EDGAR </font>
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			<font style="display: inline;">U.S. Securities and Exchange Commission</font><br /><font style="display: inline;">Division of Corporation Finance</font><br /><font style="display: inline;">100 F Street, N.E.</font><br /><font style="display: inline;">Washington, D.C. 20549</font><br /><font style="display: inline;">Attention</font><font style="display: inline;">:</font><font style="display: inline;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</font><font style="display: inline;">Christine Westbrook</font>
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		<p style="margin:0pt 0pt 0pt 72pt;text-align:left;border-top:1pt none #D9D9D9 ;text-indent:0pt;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 11pt">
			<font style="display: inline;">Joe McCann</font>
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			<font style="display: inline;font-weight:bold;">Re</font><font style="display: inline;font-weight:bold;">:&nbsp; </font><font style="display: inline;font-weight:bold;">Pacific Biosciences of California, Inc. </font><br /><font style="display: inline;font-weight:bold;">Registration Statement on Form S-3 </font>
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			<font style="display: inline;font-weight:bold;">Filed June 10, 2020</font><br /><font style="display: inline;font-weight:bold;"></font><font style="display: inline;font-weight:bold;">File No. 333-239071</font>
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			<font style="display: inline;font-weight:bold;">Acceleration Request</font>
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			<font style="display: inline;font-weight:bold;">Requested Date:</font><font style="display: inline;font-weight:bold;;font-size: 11pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;font-weight:bold;">July </font><font style="display: inline;font-weight:bold;">14</font><font style="display: inline;font-weight:bold;">, 2020</font>
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			<font style="display: inline;font-weight:bold;">Requested Time:</font><font style="display: inline;font-weight:bold;;font-size: 11pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 36pt 0pt 0pt;"></font><font style="display: inline;font-weight:bold;">4:00 P.M. Eastern Time</font>
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			<font style="display: inline;">Ladies and Gentlemen:</font>
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			<font style="display: inline;">Pursuant to Rule 461 under the Securities Act of 1933, as amended, </font><font style="display: inline;">Pacific Biosciences of California, Inc. </font><font style="display: inline;">(the&nbsp;&#x201C;</font><font style="display: inline;font-weight:bold;">Company</font><font style="display: inline;">&#x201D;) hereby requests that the above-referenced Registration Statement on Form S-</font><font style="display: inline;">3</font><font style="display: inline;"> (File No</font><font style="display: inline;font-weight:bold;">. &nbsp;</font><font style="display: inline;">333-239071</font><font style="display: inline;">) (the &#x201C;</font><font style="display: inline;font-weight:bold;">Registration Statement</font><font style="display: inline;">&#x201D;) be declared effective at the &#x201C;Requested Date&#x201D; and &#x201C;Requested Time&#x201D; set forth above or </font><font style="display: inline;">as soon thereafter as practicable, or </font><font style="display: inline;">at such later time as the Company may request </font><font style="display: inline;">by</font><font style="display: inline;"> telephone to the staff of the Securities and Exchange Commission.&nbsp; </font>
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			<font style="display: inline;">The Company hereby authorizes Andrew D. Hoffman of</font><font style="display: inline;"> Wilson Sonsini Goodrich &amp; Rosati, P.C., </font><font style="display: inline;">counsel for the Company, to make such request on the Company&#x2019;s behalf. </font>
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			<font style="display: inline;">The Company requests that it be notified of the effectiveness of the Registration Statement by telephone to Andrew D. Hoffman </font><font style="display: inline;">at (650) 849-3240 or ahoffman@wsgr.com.</font>
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			<font style="display: inline;">****</font>
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		<p><font size="1"> </font></p><hr size="3" style="color:#999999" width="100%" align="center"></hr><p style="page-break-after:always">&nbsp;</p><div style="width:100%">

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		<p style="margin:0pt 0pt 0pt 180pt;text-align:left;text-indent:36pt;text-justify:inter-ideograph;font-family:Times New Roman;;font-size: 11pt"><font style="display: inline;"></font><font style="display: inline;">Sincerely,</font>
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			<font style="display: inline;text-transform:uppercase;">Pacific Biosciences of California, Inc.</font>
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			<font style="display: inline;text-decoration:underline;">&#xFEFF;</font>
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			<font style="display: inline;text-decoration:underline;">&#xFEFF;</font>
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			<font style="text-indent:0pt;margin-left:0pt; padding-right:44.6pt;"><font style="display: inline;text-decoration:underline;">/s/ </font><font style="display: inline;text-decoration:underline;">Susan K. Barnes</font></font><font style="text-indent:0pt;margin-left:0pt; padding-right:4pt;text-align:left"><font style="display: inline;text-decoration:underline;"></font></font>
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		<p style="margin:0pt 0pt 0pt 216pt;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;text-indent:0pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 11pt">
			<font style="display: inline;">Susan K. Barnes</font>
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		<p style="margin:0pt 0pt 0pt 216pt;border-top:1pt none #D9D9D9 ;text-indent:0pt;text-align:justify;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 11pt">
			<font style="display: inline;">Executive Vice President and Chief Financial Officer</font>
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			<font style="display: inline;color:#000000;">cc:</font><font style="display: inline;color:#000000;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</font><font style="display: inline;color:#000000;">Michael Hunkapiller</font><font style="display: inline;color:#000000;">, Pacific Biosciences of California, Inc.</font>
		</p>
		<p style="margin:0pt;text-align:left;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;text-indent:36pt;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 11pt">
			<font style="display: inline;color:#000000;">Brett Atkins, Pacific Biosciences of California, Inc.</font>
		</p>
		<p style="margin:0pt 0pt 0pt 36pt;text-indent: -36pt;text-align:left;border-top:1pt none #D9D9D9 ;border-bottom:1pt none #D9D9D9 ;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 11pt">
			<font style="display: inline;color:#000000;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</font><font style="display: inline;color:#000000;">Donna </font><font style="display: inline;color:#000000;">M. </font><font style="display: inline;color:#000000;">Petkanics</font><font style="display: inline;color:#000000;">, Esq.</font><font style="display: inline;color:#000000;">, Wilson Sonsini Goodrich &amp; Rosati, P.C.</font>
		</p>
		<p style="margin:0pt 0pt 0pt 36pt;text-indent: -36pt;text-align:left;border-top:1pt none #D9D9D9 ;text-justify:inter-ideograph;font-family:Times New Roman;font-size: 11pt">
			<font style="display: inline;color:#000000;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;</font><font style="display: inline;color:#000000;">Andrew D. Hoffman</font><font style="display: inline;color:#000000;">, Esq.</font><font style="display: inline;color:#000000;">, Wilson Sonsini Goodrich &amp; Rosati, P.C.</font>
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end
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
