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Stockholders' Equity (Narrative) (Details)
$ / shares in Units, $ in Thousands
 1 Months Ended 12 Months Ended
Nov. 30, 2020
USD ($)
$ / shares
shares
Aug. 31, 2020
USD ($)
$ / shares
shares
Dec. 31, 2020
USD ($)
item
$ / shares
shares
Dec. 31, 2019
USD ($)
item
$ / shares
shares
Dec. 31, 2018
USD ($)
$ / shares
item
shares
Dec. 02, 2020
shares
Aug. 04, 2020
shares
Jun. 30, 2020
item
Oct. 31, 2010
$ / shares
shares
Stockholders' Equity [Line Items]                  
Common Stock, shares authorized     1,000,000,000 1,000,000,000         1,000,000,000
Common Stock, par value | $ / shares     $ 0.001 $ 0.001         $ 0.001
Preferred Stock, shares authorized     50,000,000 50,000,000         50,000,000
Preferred Stock, par value | $ / shares     $ 0.001 $ 0.001         $ 0.001
Preferred Stock, shares issued     0 0          
Preferred Stock, shares outstanding     0 0          
Common stock, dividends declared | $ / shares     $ 0            
Voting right of common stock share holders     one            
Voting right of common stock share holdes, number of votes | item     1            
Proceeds from issuance of common stock from underwritten public equity offerings, net of issuance costs | $     $ 187,479   $ 97,530        
Number of equity compensation plans | item       2       3  
Stock-based compensation cost capitalized in inventory | $     300 $ 300          
Stock-based compensation | $     $ 17,533 $ 16,401 $ 23,153        
Common Stock [Member]                  
Stockholders' Equity [Line Items]                  
Shares issued     29,356,000   30,610,000        
2010 Plan and 2010 Director Plan [Member]                  
Stockholders' Equity [Line Items]                  
Common stock remain available for issuance     10,300,000            
ESPP [Member]                  
Stockholders' Equity [Line Items]                  
Common stock remain available for issuance     5,878,770            
Percentage of outstanding common stock used to determine annual plan increase     2.00%            
Number of purchase periods | item     4            
Purchase period of ESPP     6 months            
Percentage of fair market value at which stock can be purchased     85.00%            
Weighted average fair value options vested at grant date | $ / shares     $ 1.68 $ 0 $ 1.47        
Stock-based compensation | $     $ 3,400 $ 500 $ 6,800        
Common stock purchased under plan     834,677 1,306,329 1,674,960        
Cash received from option exercises | $     $ 2,400 $ 2,700 $ 3,400        
2020 Equity Incentive Plan [Member]                  
Stockholders' Equity [Line Items]                  
Stock option grant, term     10 years            
Stock option grant, vest rate upon first anniversary     25.00%            
Stock option grant, vest rate per month thereafter     2.08%            
Shares authorized             11,000,000    
Vesting period     4 years            
2020 Inducement Equity Incentive Plan [Member]                  
Stockholders' Equity [Line Items]                  
Shares authorized           2,500,000      
Underwritten Public Equity Offering [Member]                  
Stockholders' Equity [Line Items]                  
Shares issued     29,400,000   30,600,000        
Proceeds from issuance of common stock from underwritten public equity offerings, net of issuance costs | $     $ 187,200 97,500          
Number of offerings | item     2   2        
Price per share | $ / shares     $ 6.40   $ 3.38        
Underwriting Agreement [Member]                  
Stockholders' Equity [Line Items]                  
Common Stock, par value | $ / shares $ 0.001 $ 0.001              
Public offering 6,096,112 19,430,000              
Common stock offering price per share | $ / shares $ 14.25 $ 4.47              
Public offering, option to purchase additionl shares, period 30 days 30 days              
Public offering, option to purchase additional shares, shares 914,416 2,914,500              
Shares issued 7,000,000.0 22,300,000              
Commissions, percentage of gross proceeds 6.00% 6.00%              
Proceeds from issuance of common stock from underwritten public equity offerings, net of issuance costs | $ $ 93,900 $ 93,900              
Offering costs | $ $ 300 $ 300              
Stock Options [Member]                  
Stockholders' Equity [Line Items]                  
Aggregate intrinsic value outstanding | $     $ 298,800            
Aggregate intrinsic value exercisable options | $     $ 225,600            
Stock price | $ / shares     $ 25.94            
Weighted average remaining contractual life     3 years            
Weighted average remaining contractual life for exercisable     4 years 10 months 20 days            
Vested and expected to vest, outstanding     13,677,000            
Vested and expected to vest, aggregate intrinsic value | $     $ 279,000            
Vested and expected to vest, weighted average exercise price | $ / shares     $ 5.54            
Vested and expected to vest, weighted average remaining contractual life     5 years 8 months 23 days            
Total intrinsic value of options exercised | $     $ 63,100 $ 2,600 $ 5,300        
Weighted average fair value at grant date | $ / shares     $ 4.14 $ 0 $ 1.50        
Stock-based compensation | $     $ 6,200 $ 11,000 $ 15,500        
Options granted       0          
Unrecognized compensation costs | $     9,900            
Cash received from option exercises | $     $ 43,900 $ 5,900 6,300        
Stock Options [Member] | $1.16 – 16.00 [Member]                  
Stockholders' Equity [Line Items]                  
Options expired     2,400,000            
Exercise price, lower range | $ / shares     $ 1.16 $ 1.16          
Exercise price, upper range | $ / shares     16.00 $ 16.00          
Options expired, weighted average exercise price | $ / shares     8.49            
Stock Options [Member] | $2.45 – 20.90 [Member]                  
Stockholders' Equity [Line Items]                  
Exercise price, lower range | $ / shares     2.45            
Exercise price, upper range | $ / shares     $ 20.9            
Options granted     2,852,000            
Time-Based Restricted Stock Units (RSUs) [Member]                  
Stockholders' Equity [Line Items]                  
Ratio of number of shares into which the share instrument may be converted     1            
Vesting period     4 years            
Stock-based compensation | $     $ 7,700 $ 4,900 $ 200        
Share-based Compensation Award, Tranche One, Two, Three and Four [Member] | Time-Based Restricted Stock Units (RSUs) [Member]                  
Stockholders' Equity [Line Items]                  
Vesting percentage     25.00%