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Commitments and Contingencies (Narrative) (Details) |  | 3 Months Ended | 9 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | ---
Jun. 22, 2020 item | Sep. 30, 2021 USD ($) | Sep. 30, 2020 USD ($) | Sep. 30, 2021 USD ($) | Sep. 30, 2020 USD ($) | Sep. 20, 2021 USD ($) | Dec. 31, 2020 USD ($) | Oct. 31, 2015 USD ($)
Commitments and Contingencies [Line Items] |  |  |  |  |  |  |  |
Long-term restricted cash |  | $ 4,560,000 |  | $ 4,560,000 |  |  | $ 3,500,000 |
Weighted average remaining lease term |  | 6 years |  | 6 years |  |  |  |
Weighted average discount rate |  | 6.80% |  | 6.80% |  |  |  |
Rent payments |  | $ 1,800,000 |  | $ 5,500,000 |  |  |  |
Operating lease cost |  | 1,600,000 | $ 1,600,000 | 4,700,000 | $ 4,700,000 |  |  |
Additional liability associated with indemnification obligations |  | 0 |  | 0 |  |  |  |
Operating Lease, Right-of-Use Asset |  | 45,862,000 |  | 45,862,000 |  |  | $ 29,951,000 |
Operating Lease, Liability |  | 57,082,000 |  | 57,082,000 |  |  |  |
Omniome, Inc [Member] |  |  |  |  |  |  |  |
Commitments and Contingencies [Line Items] |  |  |  |  |  |  |  |
Long-term restricted cash |  | 1,600,000 |  | 1,600,000 |  |  |  |
Operating Lease, Right-of-Use Asset |  |  |  |  |  | $ 18,100,000 |  |
Operating Lease, Liability |  |  |  |  |  | $ 18,100,000 |  |
PacBio IPR Petitions [Member] |  |  |  |  |  |  |  |
Commitments and Contingencies [Line Items] |  |  |  |  |  |  |  |
Number of petitions | item | 2 |  |  |  |  |  |  |
O’Brien Lease Agreement [Member] |  |  |  |  |  |  |  |
Commitments and Contingencies [Line Items] |  |  |  |  |  |  |  |
Long-term restricted cash |  | $ 3,000,000.0 |  | $ 3,000,000.0 |  |  |  | $ 4,500,000

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