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Pro forma adjustment to reflect acquiree's acquisition-related costs.

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Value of stock issued in private placement net of issuance costs.

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Amount of consideration transferred, consisting of acquisition-date fair value of assets transferred by the acquirer, liabilities incurred by the acquirer, and equity interest issued by the acquirer.

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Amount of liability recognized arising from contingent consideration in a business combination.

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The amount of identifiable intangible assets recognized as of the acquisition date.

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Amount before amortization of assets, excluding financial assets and goodwill, lacking physical substance with a finite life.

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Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized.

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The cash outflow for cost incurred directly with the issuance of an equity security.

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The cash inflow from the additional capital contribution to the entity.

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Business Acquisitions (Narrative) (Details) - USD ($) $ / shares in Units, $ in Thousands			3 Months Ended		9 Months Ended
	Sep. 20, 2021	Jul. 20, 2021	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Business Acquisition [Line Items]
Fair value of contingent consideration			$ 168,574		$ 168,574
Proceeds From Issuance Of Common Stock					30,121	$ 14,174
Issuance of common stock in Private Placement, net of issuance costs			294,845		294,845
Acquisition-related costs			30,726		30,726
Stock-based compensation expense			35,820	$ 4,992	61,790	$ 12,258
Income tax benefit from reduction in deferred tax assets valuation allowance					94,800
Goodwill			411,533		411,533
Omniome stock awards related to acquisition [Member]
Business Acquisition [Line Items]
Total cash paid	$ 7,400
Fair value of share consideration	6,300
Fair value of contingent consideration	$ 5,200
Issuance of common stock	226,811
Consideration	$ 18,900
Circulomics, Inc [Member]
Business Acquisition [Line Items]
Total cash paid		$ 29,500
Allocation of purchase price to intangible assets		11,360
Goodwill		$ 19,309
Finite-Lived Intangible Assets, Gross			$ 11,360		11,360
Omniome, Inc [Member]
Business Acquisition [Line Items]
Total cash paid	315,703
Fair value of share consideration	249,435
Fair value of contingent consideration	$ 168,574
Issuance of common stock	8,911,580
Consideration	$ 714,789
Price Per Share	$ 26.75
Issuance of common stock in Private Placement, net of issuance costs shares	11,214,953
Proceeds From Issuance Of Common Stock	$ 294,800
Estimated issuance costs	5,200
Acquisition-related costs	11,600				11,600
Stock-based compensation expense	18,900
Income tax benefit from reduction in deferred tax assets valuation allowance	92,200
Pro forma adjustment related to acquiree's acquisition-related costs	16,700
Since the date of acquisition, revenues					0
Since the date of acquisition, net loss					$ 1,600
Goodwill	392,224
Achievement of milestone [Member] \| Omniome stock awards related to acquisition [Member]
Business Acquisition [Line Items]
Stock options issued by PacBio in replacement of Omniome’s unvested options	4,100
Achievement of milestone [Member] \| Omniome, Inc [Member]
Business Acquisition [Line Items]
Total cash paid	100,000
Fair value of share consideration	100,000
Fair value of contingent consideration	200,000
In Process Research and Development, Intangible [Member] \| Omniome, Inc [Member]
Business Acquisition [Line Items]
Allocation of purchase price to intangible assets	400,000
Finite-Lived Intangible Assets, Gross	$ 400,000