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Income Taxes (Tables) | 12 Months Ended
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Dec. 31, 2021
Income Taxes [Abstract] |
Reconciliation of Federal Income Tax Rate | Years ended December 31, 2021 2020 2019 Statutory tax rate 21.0% 21.0% 21.0%State tax rate, net of federal benefit 5.5 (8.3) 4.9 Change in valuation allowance (4.9) 6.3 (27.5) Tax credits 2.5 (3.6) 2.2 Stock-based compensation 10.9 (15.2) (0.8) Merger Expenses (0.9) - - Other (0.1) (0.2) 0.2 Total 34.0% 0.0% (0.0)%
Reconciliation of Deferred Tax Assets and Liabilities | December 31,Deferred tax assets:2021 2020Net operating loss carryforwards$ 378,035 $ 233,225Research and development credits 60,672 49,179Accruals and reserves 10,822 6,337Stock-based compensation 12,838 9,717ASC 842 Operating lease liability 13,105 9,870Total deferred tax assets 475,472 308,328Less: Valuation allowance (366,940) (300,505)Total deferred tax assets: 108,532 7,823Intangibles (97,345) —Fixed assets (1,523) (786)ASC 842 Operating lease right-of-use assets (10,502) (7,037)Total deferred tax liabilities (109,370) (7,823)Net deferred tax assets $ (838) $ —
Reconciliation of Unrecognized Tax Benefit Accounts | Balance as of December 31, 2018$ 20,447Decrease in balance related to tax positions taken in prior year —Increase in balance related to tax positions taken during current year 1,532Balance as of December 31, 2019$ 21,979Decrease in balance related to tax positions taken in prior year (17,255)Increase in balance related to tax positions taken during current year 1,230Balance as of December 31, 2020$ 5,954Increase in balance related to tax positions taken in prior year 189Increase in balance related to tax positions taken during current year 2,192Balance as of December 31, 2021$ 8,335

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