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Summary of Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2022

Summary of Significant Accounting Policies [Abstract]

Summary of Assets and Liabilities Measured at Fair Value on a Recurring Basis

	March 31, 2022												December 31, 2021
(in thousands)	Level 1			Level 2			Level 3			Total			Level 1			Level 2			Level 3			Total
Assets
Cash and cash equivalents:
Cash and money market funds	$	227,251		$	—		$	—		$	227,251		$	327,315		$	—		$	—		$	327,315
Commercial paper		—			143,958			—			143,958			—			133,185			—			133,185
U.S. government & agency securities		—			32,377			—			32,377			—			225			—			225
U.S. Treasury securities		—			24,988			—			24,988			—			—			—			—
Total cash and cash equivalents		227,251			201,323			—			428,574			327,315			133,410			—			460,725
Investments:
Commercial paper		—			141,976			—			141,976			—			187,632			—			187,632
Corporate debt securities		—			5,313			—			5,313			—			8,968			—			8,968
U.S. government & agency securities		—			386,912			—			386,912			—			387,075			—			387,075
Total investments		—			534,201			—			534,201			—			583,675			—			583,675
Short-term restricted cash:
Cash		500			—			—			500			500			—			—			500
Long-term restricted cash:
Cash		4,982			—			—			4,982			4,592			—			—			4,592
Total assets measured at fair value	$	232,733		$	735,524		$	—		$	968,257		$	332,407		$	717,085		$	—		$	1,049,492
Liabilities
Contingent consideration	$	—		$	—		$	168,654		$	168,654		$	—		$	—		$	169,717		$	169,717
Total liabilities measured at fair value	$	—		$	—		$	168,654		$	168,654		$	—		$	—		$	169,717		$	169,717

Computation of Basic and Diluted Net Loss per Share

	Three Months Ended March 31,
	2022			2021
Numerator:
Net loss	$	(81,499)		$	(87,435)
Denominator:
Basic
Weighted average shares used in computing basic net loss		222,289			194,790
Basic net loss per share	$	(0.37)		$	(0.45)
Diluted
Weighted average shares used in computing diluted net loss per share		222,289			194,790
Diluted net loss per share	$	(0.37)		$	(0.45)

Anti-dilutive Shares Excluded from Computation of Diluted Net Income (Loss) per Share

	Three Months Ended March 31,
(in thousands)	2022		2021
Shares issuable upon conversion of convertible senior notes	20,690		20,690
Options to purchase common stock	15,851		12,332
RSUs	8,875		6,527
ESPP shares	2,026		2,336

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Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities.

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