<SEC-DOCUMENT>0001104659-22-046019-index.html : 20220414
<SEC-HEADER>0001104659-22-046019.hdr.sgml : 20220414
<ACCEPTANCE-DATETIME>20220414161219
ACCESSION NUMBER:		0001104659-22-046019
CONFORMED SUBMISSION TYPE:	DEF 14A
PUBLIC DOCUMENT COUNT:		11
CONFORMED PERIOD OF REPORT:	20220525
FILED AS OF DATE:		20220414
DATE AS OF CHANGE:		20220414

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
		CENTRAL INDEX KEY:			0001299130
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				161590339
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		DEF 14A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-34899
		FILM NUMBER:		22827381

	BUSINESS ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-521-8000

	MAIL ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PACIFIC BIOSCIENCES OF CALIFORNIA INC
		DATE OF NAME CHANGE:	20050829

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NANOFLUIDICS INC
		DATE OF NAME CHANGE:	20040729
</SEC-HEADER>
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<TYPE>DEF 14A
<SEQUENCE>1
<FILENAME>tm2212363-1_def14a.htm
<DESCRIPTION>DEF 14A
<TEXT>
Document 1 - file: tm2212363-1_def14a.htm

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<SEQUENCE>2
<FILENAME>lg_pacbio-4c.jpg
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<TEXT>
Document 2 - file: lg_pacbio-4c.jpg

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<SEQUENCE>3
<FILENAME>sg_christian-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: sg_christian-4c.jpg

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<FILENAME>sg_brett-bw.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: sg_brett-bw.jpg

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<FILENAME>tm2212363d1-lc_comparbwlr.jpg
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<TEXT>
Document 5 - file: tm2212363d1-lc_comparbwlr.jpg

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<TEXT>
Document 6 - file: tm2212363d1-icon_wedo4c.jpg

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<FILENAME>tm2212363d1-icon_weavoid4c.jpg
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<TEXT>
Document 7 - file: tm2212363d1-icon_weavoid4c.jpg

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Document 8 - file: tm2212363d1-icon_tick4c.jpg

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<TEXT>
Document 9 - file: tm2212363d1-icon_wrong4c.jpg

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<TEXT>
Document 10 - file: tm2212363d1-px_01page4c.jpg

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<TEXT>
Document 11 - file: tm2212363d1-px_02page4c.jpg

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