<SEC-DOCUMENT>0001193125-22-058220-index.html : 20220228
<SEC-HEADER>0001193125-22-058220.hdr.sgml : 20220228
<ACCEPTANCE-DATETIME>20220228170946
ACCESSION NUMBER:		0001193125-22-058220
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		8
FILED AS OF DATE:		20220228
DATE AS OF CHANGE:		20220228
EFFECTIVENESS DATE:		20220228

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
		CENTRAL INDEX KEY:			0001299130
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				161590339
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-263101
		FILM NUMBER:		22691265

	BUSINESS ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025
		BUSINESS PHONE:		650-521-8000

	MAIL ADDRESS:	
		STREET 1:		1305 O'BRIEN DRIVE
		CITY:			MENLO PARK
		STATE:			CA
		ZIP:			94025

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	PACIFIC BIOSCIENCES OF CALIFORNIA INC
		DATE OF NAME CHANGE:	20050829

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NANOFLUIDICS INC
		DATE OF NAME CHANGE:	20040729
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>d292548ds8.htm
<DESCRIPTION>REGISTRATION STATEMENT ON FORM S-8
<TEXT>
Document 1 - file: d292548ds8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>d292548dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: d292548dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>d292548dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 3 - file: d292548dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.3
<SEQUENCE>4
<FILENAME>d292548dex233.htm
<DESCRIPTION>EX-23.3
<TEXT>
Document 4 - file: d292548dex233.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>5
<FILENAME>d292548dexfilingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 5 - file: d292548dexfilingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>g292548g0228182659863.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: g292548g0228182659863.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>g292548g0228182700129.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: g292548g0228182700129.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>g292548g0228182700785.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: g292548g0228182700785.jpg

</DOCUMENT>
</SEC-DOCUMENT>