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    ACCESSION NUMBER:		0001104659-22-057132
    CONFORMED SUBMISSION TYPE:	DEFA14A
    PUBLIC DOCUMENT COUNT:		15
    FILED AS OF DATE:		20220509
    DATE AS OF CHANGE:		20220506

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			PACIFIC BIOSCIENCES OF CALIFORNIA, INC.
    		CENTRAL INDEX KEY:			0001299130
    		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
    		IRS NUMBER:				161590339
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEFA14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-34899
    		FILM NUMBER:		22903051

    	BUSINESS ADDRESS:
    		STREET 1:		1305 O'BRIEN DRIVE
    		CITY:			MENLO PARK
    		STATE:			CA
    		ZIP:			94025
    		BUSINESS PHONE:		650-521-8000

    	MAIL ADDRESS:
    		STREET 1:		1305 O'BRIEN DRIVE
    		CITY:			MENLO PARK
    		STATE:			CA
    		ZIP:			94025

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	PACIFIC BIOSCIENCES OF CALIFORNIA INC
    		DATE OF NAME CHANGE:	20050829

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	NANOFLUIDICS INC
    		DATE OF NAME CHANGE:	20040729
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