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Balance Sheet Components (Narrative) (Details) - USD ($)
 1 Months Ended 12 Months Ended
Sep. 30, 2021
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2018
Sep. 20, 2021
Balance Sheet Components [Line Items]            
Percentage of fee to prepay debt   4.00%        
Long-term restricted cash   $ 2,922,000 $ 4,592,000      
Goodwill   409,974,000 409,974,000      
Amortization of intangible assets   900,000 400,000 $ 0    
Depreciation   9,480,000 7,199,000 6,428,000 $ 6,400,000  
Inventory reserves   6,027,000 678,000 $ 527,000    
Deferred revenue, current   30,498,000 10,977,000      
Deferred revenue, non-current   1,794,000 25,049,000      
Prepaid expenses and other current assets   10,289,000 $ 7,394,000      
Notes Payable   2,300,000        
Notes payable, current   1,800,000        
Long Term Notes Payable   500,000        
Interest Expense   $ 600,000        
Standard Product Warranty Description   one-year warranty on instruments        
Omniome, Inc [Member]            
Balance Sheet Components [Line Items]            
Goodwill   $ 410,000,000.0       $ 390,665,000
Short term debt acquired $ 1,300,000          
Long-term debt acquired $ 3,000,000.0          
Debt Instrument, Term 43 months          
Debt Instrument Interest Rate Stated Percentage 17.00%          
Omniome, Inc [Member] | In-process research and development indefinite lived [Member]            
Balance Sheet Components [Line Items]            
Indefinite-lived Intangible Assets (Excluding Goodwill) $ 400,000,000          
Service [Member]            
Balance Sheet Components [Line Items]            
Deferred revenue   32,300,000        
Deferred revenue, current   30,500,000        
Deferred revenue, non-current   1,800,000        
Revenue recognized   $ 13,000,000.0        
Deferred service revenue, noncurrent, recognition period   6 years        
Invitae Corporation [Member]            
Balance Sheet Components [Line Items]            
Deferred revenue, current   $ 21,400,000