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Consolidated Statements of Stockholders’ Equity - USD ($)
shares in Thousands, $ in Thousands
Common Stock [Member]
Additional Paid-In Capital [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Deficit [Member]
Revision of Prior Period, Accounting Standards Update, Adjustment [Member]
Accumulated Deficit [Member]
Revision of Prior Period, Accounting Standards Update, Adjustment [Member]
Total
Balance at Dec. 31, 2019 $ 153 $ 1,120,999 $ 5   $ (1,066,240)   $ 54,917
Balance, shares at Dec. 31, 2019 153,119            
Net (loss) income         29,403   29,403
Other comprehensive gain (loss)     80       80
Issuance of common stock in conjunction with equity plans $ 10 46,350         46,360
Issuance of common stock in conjunction with equity plans, shares 9,819            
Issuance of common stock from Underwritten Public Equity Offerings, net of issuance costs 29,356            
Issuance of common stock from underwritten Public Equity Offering, net of issuance costs $ 29 187,201         187,230
Share-based compensation expense   17,533         17,533
Balance (ASC 326 adoption effect [Member]) at Dec. 31, 2020       $ (32)   $ (32)  
Balance at Dec. 31, 2020 $ 192 1,372,083 85   (1,036,869)   335,491
Balance, shares at Dec. 31, 2020 192,294            
Net (loss) income         (181,223)   (181,223)
Other comprehensive gain (loss)     (1,172)       (1,172)
Issuance of common stock in conjunction with equity plans $ 9 31,797         31,806
Issuance of common stock in conjunction with equity plans, shares 8,557            
Issuance of common stock in Private Placement, net of issuance costs $ 11 294,834         294,845
Issuance of common stock in Private Placement, net of issuance costs, Shares 11,215            
Issuance of common stock in acquisition of Omniome $ 9 237,876         237,885
Issuance of common stock in acquisition of Omniome, shares 8,912            
Share-based compensation expense   73,355         73,355
Balance at Dec. 31, 2021 $ 221 2,009,945 (1,087)   (1,218,092)   $ 790,987
Balance, shares at Dec. 31, 2021 220,978           220,978
Net (loss) income         (314,248)   $ (314,248)
Other comprehensive gain (loss)     (3,678)       (3,678)
Issuance of common stock in conjunction with equity plans $ 6 11,224         11,230
Issuance of common stock in conjunction with equity plans, shares 5,527            
Share-based compensation expense   78,613         78,613
Balance at Dec. 31, 2022 $ 227 $ 2,099,782 $ (4,765)   $ (1,532,340)   $ 562,904
Balance, shares at Dec. 31, 2022 226,505           226,505