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FINANCIAL INSTRUMENTS (Tables)
3 Months Ended
Mar. 31, 2023
Investments, All Other Investments [Abstract]  
Summary of Assets and Liabilities Measured at Fair Value on a Recurring Basis
The following table sets forth the fair value of our financial assets and liabilities that were measured on a recurring basis (in thousands):
March 31, 2023December 31, 2022
Level 1Level 2Level 3TotalLevel 1Level 2Level 3Total
Assets
Cash and cash equivalents $103,753 $250,081 $— $353,834 $137,636 $187,453 $— $325,089 
Investments:
Commercial paper — 109,873 — 109,873 — 127,302 — 127,302 
Corporate debt securities — 87,381 — 87,381 — 49,491 — 49,491 
U.S. government & agency securities— 323,804 — 323,804 — 270,436 — 270,436 
Total investments — 521,058 — 521,058 — 447,229 — 447,229 
Short-term restricted cash300 — — 300 300 — — 300 
Long-term restricted cash2,922 — — 2,922 2,922 — — 2,922 
Total assets measured at fair value $106,975 $771,139 $— $878,114 $140,858 $634,682 $— $775,540 
Liabilities
Contingent consideration$— $— $184,350 $184,350 $— $— $172,094 $172,094 
Total liabilities measured at fair value $— $— $184,350 $184,350 $— $— $172,094 $172,094 
Changes in the Estimated Fair Value of Contingent Consideration Liability
Changes in the estimated fair value of the contingent consideration liability for the three months ended March 31, 2023 were as follows (in thousands):
Level 3
Beginning balance as of December 31, 2022$172,094 
Change in estimated fair value12,256 
Ending balance as of March 31, 2023$184,350 
Summary of Cash, Cash Equivalents and Investments
The following tables summarize our cash, cash equivalents and investments (in thousands):
As of March 31, 2023
Amortized
Cost
Gross
unrealized
gains
Gross
unrealized
losses
Fair
Value
Cash and cash equivalents353,837 24 (27)353,834 
Investments:
Commercial paper 110,009 17 (153)109,873 
Corporate debt securities 87,426 299 (344)87,381 
U.S. government & agency securities325,544 576 (2,316)323,804 
Total investments 522,979 892 (2,813)521,058 
Total cash, cash equivalents and investments $876,816 $916 $(2,840)$874,892 
Short-term restricted cash$300 $— $— $300 
Long-term restricted cash$2,922 $— $— $2,922 
As of December 31, 2022
Amortized
Cost
Gross
unrealized
gains
Gross
unrealized
losses
Fair
Value
Cash and cash equivalents325,144 (61)325,089 
Investments:
Commercial paper127,626 (333)127,302 
Corporate debt securities49,998 — (507)49,491 
U.S. government & agency securities274,315 (3,880)270,436 
Total investments451,939 10 (4,720)447,229 
Total cash, cash equivalents and investments$777,083 $16 $(4,781)$772,318 
Short-term restricted cash$300 $— $— $300 
Long-term restricted cash$2,922 $— $— $2,922 

The following table summarizes the contractual maturities of our cash equivalents and available-for-sale investments, excluding money market funds, as of March 31, 2023 (in thousands):
Fair Value
Due in one year or less $634,191 
Due after one year through five years 136,948 
Total$771,139