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Cover - shares
 6 Months Ended
Jun. 30, 2023
Jul. 31, 2023
Cover [Abstract]    
Document Type 10-Q  
Document Quarterly Report true  
Document Period End Date Jun. 30, 2023  
Document Transition Report false  
Entity File Number 001-34899  
Entity Registrant Name Pacific Biosciences of California, Inc.  
Entity Incorporation, State or Country Code DE  
Entity Tax Identification Number 16-1590339  
Entity Address, Address Line One 1305 O’Brien Drive  
Entity Address, City or Town Menlo Park  
Entity Address, State or Province CA  
Entity Address, Postal Zip Code 94025  
City Area Code 650  
Local Phone Number 521-8000  
Title of 12(b) Security Common Stock, par value $0.001 per share  
Trading Symbol PACB  
Security Exchange Name NASDAQ  
Entity Current Reporting Status Yes  
Entity Interactive Data Current Yes  
Entity Filer Category Large Accelerated Filer  
Entity Small Business false  
Entity Emerging Growth Company false  
Entity Shell Company false  
Entity Common Stock, Shares Outstanding   250,558,293
Entity Central Index Key 0001299130  
Current Fiscal Year End Date --12-31  
Document Fiscal Year Focus 2023  
Document Fiscal Period Focus Q2  
Amendment Flag false