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Condensed Consolidated Statements of Stockholders’ Equity - USD ($)
shares in Thousands, $ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive (Loss) Income
Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2021   220,978      
Beginning balance at Dec. 31, 2021 $ 790,987 $ 221 $ 2,009,945 $ (1,087) $ (1,218,092)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (152,893)       (152,893)
Other comprehensive income (loss) (4,370)     (4,370)  
Issuance of common stock in conjunction with equity plans (in shares)   3,778      
Issuance of common stock in conjunction with equity plans 6,440 $ 4 6,436    
Share-based compensation expense 41,722   41,722    
Ending balance (in shares) at Jun. 30, 2022   224,756      
Ending balance at Jun. 30, 2022 681,886 $ 225 2,058,103 (5,457) (1,370,985)
Beginning balance (in shares) at Mar. 31, 2022   224,329      
Beginning balance at Mar. 31, 2022 734,578 $ 224 2,038,030 (4,085) (1,299,591)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (71,394)       (71,394)
Other comprehensive income (loss) (1,372)     (1,372)  
Issuance of common stock in conjunction with equity plans (in shares)   427      
Issuance of common stock in conjunction with equity plans 848 $ 1 847    
Share-based compensation expense 19,226   19,226    
Ending balance (in shares) at Jun. 30, 2022   224,756      
Ending balance at Jun. 30, 2022 $ 681,886 $ 225 2,058,103 (5,457) (1,370,985)
Beginning balance (in shares) at Dec. 31, 2022 226,505 226,505      
Beginning balance at Dec. 31, 2022 $ 562,904 $ 227 2,099,782 (4,765) (1,532,340)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (157,848)       (157,848)
Other comprehensive income (loss) 2,079     2,079  
Issuance of common stock from Underwritten Public Equity Offering, net of issuance costs (in shares)   20,125      
Issuance of common stock from Underwritten Public Equity Offering, net of issuance costs 189,200 $ 20 189,180    
Issuance of common stock in conjunction with equity plans (in shares)   3,843      
Issuance of common stock in conjunction with equity plans 9,821 $ 3 9,818    
Share-based compensation expense $ 35,843   35,843    
Ending balance (in shares) at Jun. 30, 2023 250,473 250,473      
Ending balance at Jun. 30, 2023 $ 641,999 $ 250 2,334,623 (2,686) (1,690,188)
Beginning balance (in shares) at Mar. 31, 2023   249,803      
Beginning balance at Mar. 31, 2023 692,117 $ 250 2,314,146 (1,924) (1,620,355)
Increase (Decrease) in Stockholders' Equity [Roll Forward]          
Net loss (69,833)       (69,833)
Other comprehensive income (loss) (762)     (762)  
Issuance of common stock in conjunction with equity plans (in shares)   670      
Issuance of common stock in conjunction with equity plans 2,586   2,586    
Share-based compensation expense $ 17,891   17,891    
Ending balance (in shares) at Jun. 30, 2023 250,473 250,473      
Ending balance at Jun. 30, 2023 $ 641,999 $ 250 $ 2,334,623 $ (2,686) $ (1,690,188)