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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2024
Mar. 31, 2023
Cash flows from operating activities    
Net loss $ (78,178) $ (88,015)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation 3,240 2,755
Amortization of intangible assets 6,853 234
Amortization of right-of-use assets 1,921 1,527
Share-based compensation expense 19,525 17,952
Accretion of discount and amortization of premium on marketable securities, net (4,031) (2,155)
Change in the estimated fair value of contingent consideration (70) 12,256
Inventory provision 3 3,521
Other 403 363
Changes in assets and liabilities    
Accounts receivable, net 6,292 (10,803)
Inventory, net (11,655) (13,319)
Prepaid expenses and other assets 3,051 (6,888)
Accounts payable 6,644 5,068
Accrued expenses (23,753) (13,186)
Deferred revenue 1,601 423
Operating lease liabilities (2,376) (1,969)
Other liabilities (5,152) (2,455)
Net cash used in operating activities (75,682) (94,691)
Cash flows from investing activities    
Purchase of property and equipment (3,879) (3,721)
Purchases of investments (191,907) (233,291)
Sales of investments 0 595
Maturities of investments 161,650 163,864
Net cash used in investing activities (34,136) (72,553)
Cash flows from financing activities    
Proceeds from issuance of common stock under equity offerings, net of issuance costs 0 189,200
Proceeds from issuance of common stock from equity plans 6,891 7,235
Notes payable principal payoff (338) (446)
Net cash provided by financing activities 6,553 195,989
Net (decrease) increase in cash, cash equivalents, and restricted cash (103,265) 28,745
Cash, cash equivalents, and restricted cash at beginning of period 182,633 328,311
Cash, cash equivalents, and restricted cash at end of period 79,368 357,056
Cash and cash equivalents at end of period 76,646 353,834
Restricted cash at end of period 2,722 3,222
Cash, cash equivalents, and restricted cash at end of period $ 79,368 $ 357,056