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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
3 Months Ended 6 Months Ended 12 Months Ended
Jun. 30, 2024
Mar. 31, 2024
Jun. 30, 2023
Jun. 30, 2024
Jun. 30, 2023
Dec. 31, 2023
Cash flows from operating activities            
Net loss $ (173,319,000)   $ (69,833,000) $ (251,497,000) $ (157,848,000)  
Adjustments to reconcile net loss to net cash used in operating activities            
Depreciation       6,739,000 5,584,000  
Amortization of acquired intangible assets       13,706,000 466,000  
Amortization of right-of-use assets       5,858,000 3,330,000  
Share-based compensation expense       36,744,000 35,843,000  
Goodwill impairment 93,200,000 $ 0 0 93,200,000 0  
Accretion of discount and amortization of premium on marketable securities, net       (7,572,000) (6,113,000)  
Change in the estimated fair value of contingent consideration 0   1,975,000 (70,000) 14,231,000  
Loss on extinguishment of debt 0   2,033,000 0 2,033,000  
Inventory provision       3,922,000 4,295,000  
Other       702,000 369,000  
Changes in assets and liabilities            
Accounts receivable, net       4,182,000 (5,248,000)  
Inventory, net       (16,767,000) (19,703,000)  
Prepaid expenses and other assets       3,559,000 (6,085,000)  
Accounts payable       3,390,000 4,262,000  
Accrued expenses       (23,250,000) (5,956,000)  
Deferred revenue       3,046,000 (2,317,000)  
Operating lease liabilities       (4,748,000) (4,114,000)  
Other liabilities       (1,089,000) 539,000  
Net cash used in operating activities       (129,945,000) (136,432,000)  
Cash flows from investing activities            
Purchase of property and equipment       (5,358,000) (5,989,000)  
Purchases of investments       (303,564,000) (476,879,000)  
Sales of investments       0 595,000  
Maturities of investments       351,623,000 311,129,000  
Net cash provided by (used in) investing activities       42,701,000 (171,144,000)  
Cash flows from financing activities            
Proceeds from issuance of common stock under equity offerings, net of issuance costs       0 189,200,000  
Proceeds from issuance of common stock from equity plans       6,891,000 9,821,000  
Payment of debt issuance costs       0 (6,836,000)  
Notes payable principal payoff       (490,000) (911,000)  
Net cash provided by financing activities       6,401,000 191,274,000  
Net decrease in cash, cash equivalents, and restricted cash       (80,843,000) (116,302,000)  
Cash, cash equivalents, and restricted cash at beginning of period   $ 182,633,000   182,633,000 328,311,000 $ 328,311,000
Cash, cash equivalents, and restricted cash at end of period 101,790,000   212,009,000 101,790,000 212,009,000 182,633,000
Cash and cash equivalents at end of period 99,526,000   209,287,000 99,526,000 209,287,000 179,911,000
Restricted cash at end of period 2,264,000   2,722,000 2,264,000 2,722,000  
Cash, cash equivalents, and restricted cash at end of period $ 101,790,000   $ 212,009,000 $ 101,790,000 $ 212,009,000 $ 182,633,000