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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2025 | Mar. 31, 2024
Cash flows from operating activities |  |
Net loss | $ (426,075) | $ (78,178)
Adjustments to reconcile net loss to net cash used in operating activities |  |
Depreciation | 5,131 | 3,240
Amortization of intangible assets | 366,390 | 6,853
Amortization of right-of-use assets | 1,258 | 1,921
Share-based compensation expense | 9,201 | 19,525
Impairment charges | 15,000 | 0
Accretion of discount and amortization of premium on marketable securities, net | (1,706) | (4,031)
Change in the estimated fair value of contingent consideration | (18,700) | (70)
Inventory provision | 7,659 | 3
Deferred income taxes | (546) | 0
Other | 719 | 403
Changes in assets and liabilities |  |
Accounts receivable, net | (4,121) | 6,292
Inventory, net | (2,538) | (11,655)
Prepaid expenses and other assets | 3,426 | 3,051
Accounts payable | (1,525) | 6,644
Accrued expenses | 311 | (23,753)
Deferred revenue | 1,332 | 1,601
Operating lease liabilities | (1,618) | (2,376)
Other liabilities | 2,346 | (5,152)
Net cash used in operating activities | (44,056) | (75,682)
Cash flows from investing activities |  |
Purchases of property and equipment | (1,389) | (3,879)
Purchases of intangible assets | (5,000) | 0
Purchases of investments | (61,820) | (191,907)
Maturities of investments | 113,443 | 161,650
Net cash provided by (used in) investing activities | 45,234 | (34,136)
Cash flows from financing activities |  |
Proceeds from issuance of common stock from equity plans | 1,959 | 6,891
Notes payable principal payoff | 0 | (338)
Net cash provided by financing activities | 1,959 | 6,553
Net increase (decrease) in cash, cash equivalents, and restricted cash | 3,137 | (103,265)
Cash, cash equivalents, and restricted cash at beginning of period | 57,592 | 182,633
Cash, cash equivalents, and restricted cash at end of period | 60,729 | 79,368
Cash and cash equivalents at end of period | 58,507 | 76,646
Restricted cash at end of period | 2,222 | 2,722
Cash, cash equivalents, and restricted cash at end of period | 60,729 | 79,368
Supplemental disclosure of non-cash investing and financing activities |  |
Right-of-use asset and lease liability recognized due to lease extension | $ 29,575 | $ 0

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