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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2025 | Jun. 30, 2024
Cash flows from operating activities |  |
Net loss | $ (468,005) | $ (251,497)
Adjustments to reconcile net loss to net cash used in operating activities |  |
Depreciation | 7,790 | 6,739
Amortization of intangible assets | 367,409 | 13,706
Amortization of right-of-use assets | 2,162 | 5,858
Share-based compensation expense | 21,096 | 36,744
Impairment charges | 15,000 | 93,200
Accretion of discount and amortization of premium on marketable securities, net | (2,982) | (7,572)
Change in the estimated fair value of contingent consideration | (18,700) | (70)
Inventory provision | 8,542 | 3,922
Deferred income taxes | (546) | 0
Other | 1,059 | 702
Changes in assets and liabilities |  |
Accounts receivable, net | (4,733) | 4,182
Inventory, net | (3,868) | (16,767)
Prepaid expenses and other assets | 6,809 | 3,559
Accounts payable | (505) | 3,390
Accrued expenses | (2,407) | (23,250)
Deferred revenue | 808 | 3,046
Operating lease liabilities | (1,730) | (4,748)
Other liabilities | (632) | (1,089)
Net cash used in operating activities | (73,433) | (129,945)
Cash flows from investing activities |  |
Purchases of property and equipment | (1,939) | (5,358)
Purchases of intangible assets | (5,000) | 0
Purchases of investments | (117,992) | (303,564)
Maturities of investments | 195,448 | 351,623
Net cash provided by investing activities | 70,517 | 42,701
Cash flows from financing activities |  |
Proceeds from issuance of common stock from equity plans | 1,959 | 6,891
Notes payable principal payoff | 0 | (490)
Net cash provided by financing activities | 1,959 | 6,401
Net decrease in cash, cash equivalents, and restricted cash | (957) | (80,843)
Cash, cash equivalents, and restricted cash at beginning of period | 57,592 | 182,633
Cash, cash equivalents, and restricted cash at end of period | 56,635 | 101,790
Cash and cash equivalents at end of period | 54,803 | 99,526
Restricted cash at end of period | 1,832 | 2,264
Cash, cash equivalents, and restricted cash at end of period | 56,635 | 101,790
Supplemental disclosure of non-cash investing and financing activities |  |
Right-of-use asset and lease liability recognized due to lease extension | $ 29,575 | $ 0

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