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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2025 | Sep. 30, 2024
Cash flows from operating activities |  |
Net loss | $ (506,005) | $ (312,222)
Adjustments to reconcile net loss to net cash used in operating activities |  |
Depreciation | 10,251 | 10,932
Amortization of intangible assets | 368,429 | 20,558
Amortization of right-of-use assets | 3,083 | 10,912
Share-based compensation expense | 32,080 | 55,003
Impairment charges | 15,000 | 93,200
Accretion of discount and amortization of premium on marketable securities, net | (3,905) | (10,663)
Change in the estimated fair value of contingent consideration | (18,700) | 1,100
Inventory provision | 9,768 | 3,715
Deferred income taxes | (546) | 0
Other | 1,456 | 1,002
Changes in assets and liabilities |  |
Accounts receivable, net | (3,092) | 7,232
Inventory, net | (4,926) | (15,394)
Prepaid expenses and other assets | 7,797 | 3,534
Accounts payable | 761 | (2,222)
Accrued expenses | (1,396) | (26,665)
Deferred revenue | 685 | 875
Operating lease liabilities | (661) | (9,252)
Other liabilities | (2,219) | (7,053)
Net cash used in operating activities | (92,140) | (175,408)
Cash flows from investing activities |  |
Purchases of property and equipment | (1,853) | (4,571)
Purchases of intangible assets | (5,000) | 0
Purchases of investments | (183,817) | (418,164)
Sales of investments | 0 | 8,061
Maturities of investments | 280,089 | 480,440
Net cash provided by investing activities | 89,419 | 65,766
Cash flows from financing activities |  |
Proceeds from issuance of common stock from equity plans | 3,428 | 7,703
Notes payable principal payoff | 0 | (490)
Net cash provided by financing activities | 3,428 | 7,213
Net increase (decrease) in cash, cash equivalents, and restricted cash | 707 | (102,429)
Cash, cash equivalents, and restricted cash at beginning of period | 57,592 | 182,633
Cash, cash equivalents, and restricted cash at end of period | 58,299 | 80,204
Cash and cash equivalents at end of period | 56,467 | 77,982
Restricted cash at end of period | 1,832 | 2,222
Cash, cash equivalents, and restricted cash at end of period | 58,299 | 80,204
Supplemental disclosure of non-cash investing and financing activities |  |
Right-of-use asset and lease liability recognized due to lease extension | $ 29,575 | $ 0

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