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    <loc xlink:type="locator" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityEmergingGrowthCompany" xlink:label="locator_dei_EntityEmergingGrowthCompany"/>
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    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FederalFundsSold" xml:lang="en-US">Federal funds sold</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FederalFundsSold" xlink:to="label_us-gaap_FederalFundsSold"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestBearingDepositsInBanks" xlink:label="locator_us-gaap_InterestBearingDepositsInBanks"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestBearingDepositsInBanks" xml:lang="en-US">Interest-bearing deposits with banks</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestBearingDepositsInBanks" xlink:to="label_us-gaap_InterestBearingDepositsInBanks"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsAndFederalFundsSold" xlink:label="locator_us-gaap_CashCashEquivalentsAndFederalFundsSold"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_CashCashEquivalentsAndFederalFundsSold" xml:lang="en-US">Total cash and cash equivalents</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CashCashEquivalentsAndFederalFundsSold" xml:lang="en-US">Cash, Cash Equivalents, and Federal Funds Sold</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CashCashEquivalentsAndFederalFundsSold" xlink:to="label_us-gaap_CashCashEquivalentsAndFederalFundsSold"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MarketableSecuritiesAbstract" xlink:label="locator_us-gaap_MarketableSecuritiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_MarketableSecuritiesAbstract" xml:lang="en-US">Investment securities:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_MarketableSecuritiesAbstract" xlink:to="label_us-gaap_MarketableSecuritiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecurities" xlink:label="locator_us-gaap_AvailableForSaleSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecurities" xml:lang="en-US">Investment securities available for sale</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_AvailableForSaleSecurities" xml:lang="en-US">Contractual Maturities, Total, Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecurities" xlink:to="label_us-gaap_AvailableForSaleSecurities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherInvestments" xlink:label="locator_us-gaap_OtherInvestments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherInvestments" xml:lang="en-US">Other investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_OtherInvestments" xml:lang="en-US">Total other investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_OtherInvestments" xml:lang="en-US">Other investments, at cost, Carrying Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherInvestments" xlink:to="label_us-gaap_OtherInvestments"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Investments" xlink:label="locator_us-gaap_Investments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_Investments" xml:lang="en-US">Total investment securities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_Investments" xml:lang="en-US">Investments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_Investments" xlink:to="label_us-gaap_Investments"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansReceivableHeldForSaleAmount" xlink:label="locator_us-gaap_LoansReceivableHeldForSaleAmount"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansReceivableHeldForSaleAmount" xml:lang="en-US">Mortgage loans held for sale</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansReceivableHeldForSaleAmount" xlink:to="label_us-gaap_LoansReceivableHeldForSaleAmount"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome" xlink:label="locator_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome" xml:lang="en-US">Loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome" xml:lang="en-US">Total gross loans, net of deferred fees</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/terseLabel" xlink:label="label_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome" xml:lang="en-US">Recorded investment in loans, Total</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome" xlink:to="label_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansAndLeasesReceivableAllowance" xlink:label="locator_us-gaap_LoansAndLeasesReceivableAllowance"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_LoansAndLeasesReceivableAllowance" xml:lang="en-US">Less allowance for loan losses</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedTerseLabel" xlink:label="label_us-gaap_LoansAndLeasesReceivableAllowance" xml:lang="en-US">Less-allowance for loan losses</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansAndLeasesReceivableAllowance" xml:lang="en-US">Loans and Leases Receivable, Allowance</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansAndLeasesReceivableAllowance" xlink:to="label_us-gaap_LoansAndLeasesReceivableAllowance"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansAndLeasesReceivableNetReportedAmount" xlink:label="locator_us-gaap_LoansAndLeasesReceivableNetReportedAmount"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_LoansAndLeasesReceivableNetReportedAmount" xml:lang="en-US">Loans, net</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansAndLeasesReceivableNetReportedAmount" xml:lang="en-US">Total loans, net</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansAndLeasesReceivableNetReportedAmount" xlink:to="label_us-gaap_LoansAndLeasesReceivableNetReportedAmount"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BankOwnedLifeInsurance" xlink:label="locator_us-gaap_BankOwnedLifeInsurance"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_BankOwnedLifeInsurance" xml:lang="en-US">Bank owned life insurance</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_BankOwnedLifeInsurance" xlink:to="label_us-gaap_BankOwnedLifeInsurance"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="locator_us-gaap_PropertyPlantAndEquipmentNet"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PropertyPlantAndEquipmentNet" xml:lang="en-US">Property and equipment, net</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PropertyPlantAndEquipmentNet" xlink:to="label_us-gaap_PropertyPlantAndEquipmentNet"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredIncomeTaxAssetsNet" xlink:label="locator_us-gaap_DeferredIncomeTaxAssetsNet"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DeferredIncomeTaxAssetsNet" xml:lang="en-US">Deferred income taxes</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DeferredIncomeTaxAssetsNet" xlink:to="label_us-gaap_DeferredIncomeTaxAssetsNet"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssets" xlink:label="locator_us-gaap_OtherAssets"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherAssets" xml:lang="en-US">Other assets</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherAssets" xlink:to="label_us-gaap_OtherAssets"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Assets" xlink:label="locator_us-gaap_Assets"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_Assets" xml:lang="en-US">Total assets</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_Assets" xml:lang="en-US">Total assets</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_Assets" xml:lang="en-US">Assets [Default Label]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_Assets" xlink:to="label_us-gaap_Assets"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:label="locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LiabilitiesAndStockholdersEquityAbstract" xml:lang="en-US">LIABILITIES</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LiabilitiesAndStockholdersEquityAbstract" xlink:to="label_us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Deposits" xlink:label="locator_us-gaap_Deposits"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_Deposits" xml:lang="en-US">Deposits</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_Deposits" xml:lang="en-US">Deposits, Carrying Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_Deposits" xlink:to="label_us-gaap_Deposits"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_FederalHomeLoanBankAdvancesAndRepurchaseAgreements" xlink:label="locator_sfst_FederalHomeLoanBankAdvancesAndRepurchaseAgreements"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_FederalHomeLoanBankAdvancesAndRepurchaseAgreements" xml:lang="en-US">Federal Home Loan Bank advances and other borrowings</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_FederalHomeLoanBankAdvancesAndRepurchaseAgreements" xml:lang="en-US">Amount of borrowings as of the balance sheet date from the Federal Home Loan Bank, which are primarily used to cover shortages in the required reserve balance and liquidity shortages and repurchase agreements.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_FederalHomeLoanBankAdvancesAndRepurchaseAgreements" xlink:to="label_sfst_FederalHomeLoanBankAdvancesAndRepurchaseAgreements"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_JuniorSubordinatedNotes" xlink:label="locator_us-gaap_JuniorSubordinatedNotes"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_JuniorSubordinatedNotes" xml:lang="en-US">Subordinated debentures</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_JuniorSubordinatedNotes" xlink:to="label_us-gaap_JuniorSubordinatedNotes"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLiabilities" xlink:label="locator_us-gaap_OtherLiabilities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherLiabilities" xml:lang="en-US">Other liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherLiabilities" xlink:to="label_us-gaap_OtherLiabilities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Liabilities" xlink:label="locator_us-gaap_Liabilities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_Liabilities" xml:lang="en-US">Total liabilities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_Liabilities" xml:lang="en-US">Liabilities [Default Label]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_Liabilities" xlink:to="label_us-gaap_Liabilities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityAbstract" xlink:label="locator_us-gaap_StockholdersEquityAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StockholdersEquityAbstract" xml:lang="en-US">SHAREHOLDERS' EQUITY</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StockholdersEquityAbstract" xlink:to="label_us-gaap_StockholdersEquityAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockValueOutstanding" xlink:label="locator_us-gaap_PreferredStockValueOutstanding"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PreferredStockValueOutstanding" xml:lang="en-US">Preferred stock, par value $.01 per share, 10,000,000 shares authorized</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PreferredStockValueOutstanding" xlink:to="label_us-gaap_PreferredStockValueOutstanding"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockValueOutstanding" xlink:label="locator_us-gaap_CommonStockValueOutstanding"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CommonStockValueOutstanding" xml:lang="en-US">Common stock, par value $.01 per share, 10,000,000 shares authorized, 7,899,931 and 7,772,748 shares issued and outstanding at June 30, 2021 and December 31, 2020, respectively</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CommonStockValueOutstanding" xlink:to="label_us-gaap_CommonStockValueOutstanding"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonvestedRestrictedStockValue" xlink:label="locator_sfst_NonvestedRestrictedStockValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_sfst_NonvestedRestrictedStockValue" xml:lang="en-US">Nonvested restricted stock</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonvestedRestrictedStockValue" xml:lang="en-US">Aggregate value of restricted common stock, which are yet to be vested.</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonvestedRestrictedStockValue" xml:lang="en-US">Nonvested Restricted Stock, Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonvestedRestrictedStockValue" xlink:to="label_sfst_NonvestedRestrictedStockValue"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="locator_us-gaap_AdditionalPaidInCapital"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AdditionalPaidInCapital" xml:lang="en-US">Additional paid-in capital</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AdditionalPaidInCapital" xlink:to="label_us-gaap_AdditionalPaidInCapital"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xml:lang="en-US">Accumulated other comprehensive income</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:to="label_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="locator_us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_RetainedEarningsAccumulatedDeficit" xml:lang="en-US">Retained earnings</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_RetainedEarningsAccumulatedDeficit" xlink:to="label_us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="locator_us-gaap_StockholdersEquity"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_StockholdersEquity" xml:lang="en-US">Total shareholders' equity</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="label_us-gaap_StockholdersEquity" xml:lang="en-US">Balance</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="label_us-gaap_StockholdersEquity" xml:lang="en-US">Balance</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StockholdersEquity" xml:lang="en-US">Stockholders' Equity Attributable to Parent</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StockholdersEquity" xlink:to="label_us-gaap_StockholdersEquity"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="locator_us-gaap_LiabilitiesAndStockholdersEquity"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_LiabilitiesAndStockholdersEquity" xml:lang="en-US">Total liabilities and shareholders' equity</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LiabilitiesAndStockholdersEquity" xml:lang="en-US">Liabilities and Equity</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LiabilitiesAndStockholdersEquity" xlink:to="label_us-gaap_LiabilitiesAndStockholdersEquity"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockParOrStatedValuePerShare" xlink:label="locator_us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PreferredStockParOrStatedValuePerShare" xml:lang="en-US">Preferred stock, par value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PreferredStockParOrStatedValuePerShare" xlink:to="label_us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockSharesAuthorized" xlink:label="locator_us-gaap_PreferredStockSharesAuthorized"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PreferredStockSharesAuthorized" xml:lang="en-US">Preferred stock, shares authorized</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PreferredStockSharesAuthorized" xlink:to="label_us-gaap_PreferredStockSharesAuthorized"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockSharesIssued" xlink:label="locator_us-gaap_PreferredStockSharesIssued"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PreferredStockSharesIssued" xml:lang="en-US">Preferred stock, shares issued</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PreferredStockSharesIssued" xlink:to="label_us-gaap_PreferredStockSharesIssued"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockSharesOutstanding" xlink:label="locator_us-gaap_PreferredStockSharesOutstanding"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PreferredStockSharesOutstanding" xml:lang="en-US">Preferred stock, shares outstanding</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PreferredStockSharesOutstanding" xlink:to="label_us-gaap_PreferredStockSharesOutstanding"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare" xlink:label="locator_us-gaap_CommonStockParOrStatedValuePerShare"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CommonStockParOrStatedValuePerShare" xml:lang="en-US">Common stock, par value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CommonStockParOrStatedValuePerShare" xlink:to="label_us-gaap_CommonStockParOrStatedValuePerShare"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesAuthorized" xlink:label="locator_us-gaap_CommonStockSharesAuthorized"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CommonStockSharesAuthorized" xml:lang="en-US">Common stock, shares authorized</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CommonStockSharesAuthorized" xlink:to="label_us-gaap_CommonStockSharesAuthorized"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesIssued" xlink:label="locator_us-gaap_CommonStockSharesIssued"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CommonStockSharesIssued" xml:lang="en-US">Common stock, shares issued</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CommonStockSharesIssued" xlink:to="label_us-gaap_CommonStockSharesIssued"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding" xlink:label="locator_us-gaap_CommonStockSharesOutstanding"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CommonStockSharesOutstanding" xml:lang="en-US">Common stock, shares outstanding</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CommonStockSharesOutstanding" xlink:to="label_us-gaap_CommonStockSharesOutstanding"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementAbstract" xlink:label="locator_us-gaap_IncomeStatementAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IncomeStatementAbstract" xml:lang="en-US">Income Statement [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IncomeStatementAbstract" xlink:to="label_us-gaap_IncomeStatementAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestAndDividendIncomeOperatingAbstract" xlink:label="locator_us-gaap_InterestAndDividendIncomeOperatingAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestAndDividendIncomeOperatingAbstract" xml:lang="en-US">Interest income</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestAndDividendIncomeOperatingAbstract" xlink:to="label_us-gaap_InterestAndDividendIncomeOperatingAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestAndFeeIncomeLoansAndLeases" xlink:label="locator_us-gaap_InterestAndFeeIncomeLoansAndLeases"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_InterestAndFeeIncomeLoansAndLeases" xml:lang="en-US">Loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestAndFeeIncomeLoansAndLeases" xml:lang="en-US">Interest and Fee Income, Loans and Leases</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestAndFeeIncomeLoansAndLeases" xlink:to="label_us-gaap_InterestAndFeeIncomeLoansAndLeases"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestAndDividendIncomeSecurities" xlink:label="locator_us-gaap_InterestAndDividendIncomeSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestAndDividendIncomeSecurities" xml:lang="en-US">Investment securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestAndDividendIncomeSecurities" xlink:to="label_us-gaap_InterestAndDividendIncomeSecurities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestIncomeFederalFundsSold" xlink:label="locator_us-gaap_InterestIncomeFederalFundsSold"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestIncomeFederalFundsSold" xml:lang="en-US">Federal funds sold and interest-bearing deposits with banks</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestIncomeFederalFundsSold" xlink:to="label_us-gaap_InterestIncomeFederalFundsSold"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestAndDividendIncomeOperating" xlink:label="locator_us-gaap_InterestAndDividendIncomeOperating"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_InterestAndDividendIncomeOperating" xml:lang="en-US">Total interest income</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_InterestAndDividendIncomeOperating" xml:lang="en-US">Interest income</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestAndDividendIncomeOperating" xml:lang="en-US">Interest and Dividend Income, Operating</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestAndDividendIncomeOperating" xlink:to="label_us-gaap_InterestAndDividendIncomeOperating"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseAbstract" xlink:label="locator_us-gaap_InterestExpenseAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestExpenseAbstract" xml:lang="en-US">Interest expense</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestExpenseAbstract" xlink:to="label_us-gaap_InterestExpenseAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDeposits" xlink:label="locator_us-gaap_InterestExpenseDeposits"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_InterestExpenseDeposits" xml:lang="en-US">Deposits</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestExpenseDeposits" xml:lang="en-US">Interest Expense, Deposits</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestExpenseDeposits" xlink:to="label_us-gaap_InterestExpenseDeposits"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseBorrowings" xlink:label="locator_us-gaap_InterestExpenseBorrowings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestExpenseBorrowings" xml:lang="en-US">Borrowings</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestExpenseBorrowings" xlink:to="label_us-gaap_InterestExpenseBorrowings"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpense" xlink:label="locator_us-gaap_InterestExpense"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_InterestExpense" xml:lang="en-US">Total interest expense</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_InterestExpense" xml:lang="en-US">Interest expense</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestExpense" xml:lang="en-US">Interest Expense</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestExpense" xlink:to="label_us-gaap_InterestExpense"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="locator_us-gaap_InterestIncomeExpenseNet"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_InterestIncomeExpenseNet" xml:lang="en-US">Net interest income</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestIncomeExpenseNet" xml:lang="en-US">Net interest income (loss)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestIncomeExpenseNet" xlink:to="label_us-gaap_InterestIncomeExpenseNet"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProvisionForLoanLeaseAndOtherLosses" xlink:label="locator_us-gaap_ProvisionForLoanLeaseAndOtherLosses"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProvisionForLoanLeaseAndOtherLosses" xml:lang="en-US">Provision for (reversal of) loan losses</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_ProvisionForLoanLeaseAndOtherLosses" xml:lang="en-US">Provision for loan losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProvisionForLoanLeaseAndOtherLosses" xlink:to="label_us-gaap_ProvisionForLoanLeaseAndOtherLosses"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss" xlink:label="locator_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss" xml:lang="en-US">Net interest income after provision for loan losses</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss" xml:lang="en-US">Interest Income (Expense), after Provision for Loan Loss</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss" xlink:to="label_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoninterestIncomeAbstract" xlink:label="locator_us-gaap_NoninterestIncomeAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NoninterestIncomeAbstract" xml:lang="en-US">Noninterest income</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NoninterestIncomeAbstract" xlink:to="label_us-gaap_NoninterestIncomeAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax" xlink:label="locator_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax" xml:lang="en-US">Mortgage banking income</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax" xlink:to="label_us-gaap_RevenueFromContractWithCustomerIncludingAssessedTax"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ServiceFeesOnDepositAccounts" xlink:label="locator_sfst_ServiceFeesOnDepositAccounts"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ServiceFeesOnDepositAccounts" xml:lang="en-US">Service fees on deposit accounts</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ServiceFeesOnDepositAccounts" xml:lang="en-US">Amount of service fees on deposit accounts.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ServiceFeesOnDepositAccounts" xlink:to="label_sfst_ServiceFeesOnDepositAccounts"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ProductOrServiceOnDebitCard" xlink:label="locator_sfst_ProductOrServiceOnDebitCard"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ProductOrServiceOnDebitCard" xml:lang="en-US">ATM and debit card income</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ProductOrServiceOnDebitCard" xml:lang="en-US">Amount of product or service on debit card.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ProductOrServiceOnDebitCard" xlink:to="label_sfst_ProductOrServiceOnDebitCard"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BankOwnedLifeInsuranceIncome" xlink:label="locator_us-gaap_BankOwnedLifeInsuranceIncome"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_BankOwnedLifeInsuranceIncome" xml:lang="en-US">Income from bank owned life insurance</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_BankOwnedLifeInsuranceIncome" xml:lang="en-US">Increase in cash surrender value of bank owned life insurance</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_BankOwnedLifeInsuranceIncome" xlink:to="label_us-gaap_BankOwnedLifeInsuranceIncome"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NetLenderAndReferralFeesOnPppLoans" xlink:label="locator_sfst_NetLenderAndReferralFeesOnPppLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NetLenderAndReferralFeesOnPppLoans" xml:lang="en-US">Net lender and referral fees on PPP loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_sfst_NetLenderAndReferralFeesOnPppLoans" xml:lang="en-US">Receive referral fees</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NetLenderAndReferralFeesOnPppLoans" xml:lang="en-US">Net lender and referral fees on PPP loans</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NetLenderAndReferralFeesOnPppLoans" xlink:to="label_sfst_NetLenderAndReferralFeesOnPppLoans"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoninterestIncomeOther" xlink:label="locator_us-gaap_NoninterestIncomeOther"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NoninterestIncomeOther" xml:lang="en-US">Other income</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NoninterestIncomeOther" xlink:to="label_us-gaap_NoninterestIncomeOther"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoninterestIncome" xlink:label="locator_us-gaap_NoninterestIncome"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_NoninterestIncome" xml:lang="en-US">Total noninterest income</label>
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    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NoninterestIncome" xml:lang="en-US">Noninterest Income</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NoninterestIncome" xlink:to="label_us-gaap_NoninterestIncome"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoninterestExpenseAbstract" xlink:label="locator_us-gaap_NoninterestExpenseAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NoninterestExpenseAbstract" xml:lang="en-US">Noninterest expenses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NoninterestExpenseAbstract" xlink:to="label_us-gaap_NoninterestExpenseAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LaborAndRelatedExpense" xlink:label="locator_us-gaap_LaborAndRelatedExpense"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LaborAndRelatedExpense" xml:lang="en-US">Compensation and benefits</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LaborAndRelatedExpense" xlink:to="label_us-gaap_LaborAndRelatedExpense"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductionCosts" xlink:label="locator_us-gaap_ProductionCosts"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProductionCosts" xml:lang="en-US">Mortgage production costs</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProductionCosts" xlink:to="label_us-gaap_ProductionCosts"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OccupancyNet" xlink:label="locator_us-gaap_OccupancyNet"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OccupancyNet" xml:lang="en-US">Occupancy</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OccupancyNet" xlink:to="label_us-gaap_OccupancyNet"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_RealEstateOwnedExpenses" xlink:label="locator_sfst_RealEstateOwnedExpenses"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_RealEstateOwnedExpenses" xml:lang="en-US">Other real estate owned expenses</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_RealEstateOwnedExpenses" xml:lang="en-US">Other real estate owned expenses.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_RealEstateOwnedExpenses" xlink:to="label_sfst_RealEstateOwnedExpenses"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InformationTechnologyAndDataProcessing" xlink:label="locator_us-gaap_InformationTechnologyAndDataProcessing"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InformationTechnologyAndDataProcessing" xml:lang="en-US">Outside service and data processing costs</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InformationTechnologyAndDataProcessing" xlink:to="label_us-gaap_InformationTechnologyAndDataProcessing"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FederalDepositInsuranceCorporationPremiumExpense" xlink:label="locator_us-gaap_FederalDepositInsuranceCorporationPremiumExpense"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FederalDepositInsuranceCorporationPremiumExpense" xml:lang="en-US">Insurance</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FederalDepositInsuranceCorporationPremiumExpense" xlink:to="label_us-gaap_FederalDepositInsuranceCorporationPremiumExpense"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProfessionalFees" xlink:label="locator_us-gaap_ProfessionalFees"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProfessionalFees" xml:lang="en-US">Professional fees</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProfessionalFees" xlink:to="label_us-gaap_ProfessionalFees"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MarketingExpense" xlink:label="locator_us-gaap_MarketingExpense"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_MarketingExpense" xml:lang="en-US">Marketing</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_MarketingExpense" xlink:to="label_us-gaap_MarketingExpense"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNoninterestExpense" xlink:label="locator_us-gaap_OtherNoninterestExpense"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherNoninterestExpense" xml:lang="en-US">Other</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherNoninterestExpense" xlink:to="label_us-gaap_OtherNoninterestExpense"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoninterestExpense" xlink:label="locator_us-gaap_NoninterestExpense"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_NoninterestExpense" xml:lang="en-US">Total noninterest expenses</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NoninterestExpense" xml:lang="en-US">Noninterest expense</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NoninterestExpense" xlink:to="label_us-gaap_NoninterestExpense"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:label="locator_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xml:lang="en-US">Income before income tax expense</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xml:lang="en-US">Net income (loss) before taxes</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest" xlink:to="label_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="locator_us-gaap_IncomeTaxExpenseBenefit"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IncomeTaxExpenseBenefit" xml:lang="en-US">Income tax expense</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_IncomeTaxExpenseBenefit" xml:lang="en-US">Income tax provision (benefit)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IncomeTaxExpenseBenefit" xlink:to="label_us-gaap_IncomeTaxExpenseBenefit"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="locator_us-gaap_NetIncomeLoss"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_NetIncomeLoss" xml:lang="en-US">Net income available to common shareholders</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NetIncomeLoss" xml:lang="en-US">Net income</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_NetIncomeLoss" xml:lang="en-US">Net income (loss)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NetIncomeLoss" xlink:to="label_us-gaap_NetIncomeLoss"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareAbstract" xlink:label="locator_us-gaap_EarningsPerShareAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_EarningsPerShareAbstract" xml:lang="en-US">Earnings per common share</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_EarningsPerShareAbstract" xml:lang="en-US">Earnings Per Share [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_EarningsPerShareAbstract" xlink:to="label_us-gaap_EarningsPerShareAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareBasic" xlink:label="locator_us-gaap_EarningsPerShareBasic"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_EarningsPerShareBasic" xml:lang="en-US">Basic</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_EarningsPerShareBasic" xlink:to="label_us-gaap_EarningsPerShareBasic"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareDiluted" xlink:label="locator_us-gaap_EarningsPerShareDiluted"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_EarningsPerShareDiluted" xml:lang="en-US">Diluted</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_EarningsPerShareDiluted" xlink:to="label_us-gaap_EarningsPerShareDiluted"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:label="locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xml:lang="en-US">Weighted average common shares outstanding</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract" xlink:to="label_us-gaap_WeightedAverageNumberOfSharesOutstandingAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="locator_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xml:lang="en-US">Basic</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xml:lang="en-US">Weighted-average common shares outstanding - basic</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:to="label_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="locator_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xml:lang="en-US">Diluted</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xml:lang="en-US">Weighted-average common shares outstanding - diluted</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xml:lang="en-US">Weighted Average Number of Shares Outstanding, Diluted</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:to="label_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:label="locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xml:lang="en-US">Statement of Comprehensive Income [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract" xlink:to="label_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract" xlink:label="locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract" xml:lang="en-US">Other comprehensive income:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract" xlink:to="label_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParentAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentBeforeTaxPortionAttributableToParentAbstract" xlink:label="locator_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentBeforeTaxPortionAttributableToParentAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentBeforeTaxPortionAttributableToParentAbstract" xml:lang="en-US">Unrealized gain on securities available for sale:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentBeforeTaxPortionAttributableToParentAbstract" xlink:to="label_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentBeforeTaxPortionAttributableToParentAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax" xlink:label="locator_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax" xml:lang="en-US">Unrealized holding gain (loss) arising during the period, pretax</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax" xlink:to="label_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodBeforeTax"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax" xlink:label="locator_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax" xml:lang="en-US">Tax (expense) benefit</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax" xml:lang="en-US">OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, Tax</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax" xlink:to="label_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodTax"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesBeforeTax" xlink:label="locator_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesBeforeTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesBeforeTax" xml:lang="en-US">Reclassification of realized gain</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesBeforeTax" xml:lang="en-US">Other Comprehensive Income (Loss), Reclassification Adjustment from AOCI for Sale of Securities, before Tax</label>
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    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesTax" xlink:label="locator_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesTax" xml:lang="en-US">Tax expense</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesTax" xlink:to="label_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesTax"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:label="locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xml:lang="en-US">Other comprehensive income (loss)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xml:lang="en-US">Other comprehensive income (loss)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent" xlink:to="label_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="locator_us-gaap_ComprehensiveIncomeNetOfTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_ComprehensiveIncomeNetOfTax" xml:lang="en-US">Comprehensive income</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ComprehensiveIncomeNetOfTax" xml:lang="en-US">Comprehensive Income (Loss), Net of Tax, Attributable to Parent</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ComprehensiveIncomeNetOfTax" xlink:to="label_us-gaap_ComprehensiveIncomeNetOfTax"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementTable" xlink:label="locator_us-gaap_StatementTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StatementTable" xml:lang="en-US">Statement [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StatementTable" xlink:to="label_us-gaap_StatementTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AwardTypeAxis" xlink:label="locator_us-gaap_AwardTypeAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AwardTypeAxis" xml:lang="en-US">Award Type [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AwardTypeAxis" xlink:to="label_us-gaap_AwardTypeAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis" xlink:label="locator_us-gaap_StatementEquityComponentsAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StatementEquityComponentsAxis" xml:lang="en-US">Statement, Equity Components [Axis]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_StatementEquityComponentsAxis" xml:lang="en-US">Equity Components [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StatementEquityComponentsAxis" xlink:to="label_us-gaap_StatementEquityComponentsAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember" xlink:label="locator_us-gaap_CommonStockMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CommonStockMember" xml:lang="en-US">Common stock [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CommonStockMember" xlink:to="label_us-gaap_CommonStockMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PreferredStockMember" xlink:label="locator_us-gaap_PreferredStockMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PreferredStockMember" xml:lang="en-US">Preferred stock [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PreferredStockMember" xlink:to="label_us-gaap_PreferredStockMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonvestedRestrictedStockMember" xlink:label="locator_sfst_NonvestedRestrictedStockMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonvestedRestrictedStockMember" xml:lang="en-US">Nonvested restricted stock [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonvestedRestrictedStockMember" xml:lang="en-US">Nonvested Restricted Stock [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonvestedRestrictedStockMember" xlink:to="label_sfst_NonvestedRestrictedStockMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember" xlink:label="locator_us-gaap_AdditionalPaidInCapitalMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AdditionalPaidInCapitalMember" xml:lang="en-US">Additional paid-in capital [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AdditionalPaidInCapitalMember" xlink:to="label_us-gaap_AdditionalPaidInCapitalMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:label="locator_us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xml:lang="en-US">Accumulated other comprehensive income (loss) [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AccumulatedOtherComprehensiveIncomeMember" xlink:to="label_us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsMember" xlink:label="locator_us-gaap_RetainedEarningsMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_RetainedEarningsMember" xml:lang="en-US">Retained earnings [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_RetainedEarningsMember" xlink:to="label_us-gaap_RetainedEarningsMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementLineItems" xlink:label="locator_us-gaap_StatementLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StatementLineItems" xml:lang="en-US">Statement [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StatementLineItems" xlink:to="label_us-gaap_StatementLineItems"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharesOutstanding" xlink:label="locator_us-gaap_SharesOutstanding"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="label_us-gaap_SharesOutstanding" xml:lang="en-US">Balance, shares</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="label_us-gaap_SharesOutstanding" xml:lang="en-US">Balance, shares</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SharesOutstanding" xml:lang="en-US">Shares, Outstanding</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SharesOutstanding" xlink:to="label_us-gaap_SharesOutstanding"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised" xlink:label="locator_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised" xml:lang="en-US">Proceeds from exercise of stock options</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised" xlink:to="label_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:label="locator_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xml:lang="en-US">Proceeds from exercise of stock options, shares</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised" xlink:to="label_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures" xlink:label="locator_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures" xml:lang="en-US">Issuance of restricted stock</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures" xlink:to="label_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures" xlink:label="locator_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures" xml:lang="en-US">Issuance of restricted stock, shares</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures" xlink:to="label_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition" xlink:label="locator_us-gaap_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition" xml:lang="en-US">Compensation expense related to restricted stock, net of tax</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition" xlink:to="label_us-gaap_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationRestrictedStockUnitsRequisiteServicePeriodRecognition"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:label="locator_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xml:lang="en-US">Compensation expense related to stock options, net of tax</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue" xlink:to="label_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract" xlink:label="locator_us-gaap_StatementOfCashFlowsAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StatementOfCashFlowsAbstract" xml:lang="en-US">Statement of Cash Flows [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StatementOfCashFlowsAbstract" xlink:to="label_us-gaap_StatementOfCashFlowsAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xml:lang="en-US">Operating activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="label_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:label="locator_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xml:lang="en-US">Adjustments to reconcile net income to cash provided by (used for) operating activities:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract" xlink:to="label_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DepreciationAmortizationAndAccretionNet" xlink:label="locator_us-gaap_DepreciationAmortizationAndAccretionNet"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DepreciationAmortizationAndAccretionNet" xml:lang="en-US">Depreciation and other amortization</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DepreciationAmortizationAndAccretionNet" xlink:to="label_us-gaap_DepreciationAmortizationAndAccretionNet"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments" xlink:label="locator_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments" xml:lang="en-US">Accretion and amortization of securities discounts and premium, net</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments" xml:lang="en-US">Accretion (Amortization) of Discounts and Premiums, Investments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments" xlink:to="label_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LossOnSaleOfRealEstateOwned" xlink:label="locator_sfst_LossOnSaleOfRealEstateOwned"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LossOnSaleOfRealEstateOwned" xml:lang="en-US">Loss on sale of real estate owned</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LossOnSaleOfRealEstateOwned" xml:lang="en-US">Loss on sale of real estate owned.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LossOnSaleOfRealEstateOwned" xlink:to="label_sfst_LossOnSaleOfRealEstateOwned"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainLossOnSaleOfPropertyPlantEquipment" xlink:label="locator_us-gaap_GainLossOnSaleOfPropertyPlantEquipment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_GainLossOnSaleOfPropertyPlantEquipment" xml:lang="en-US">Gain on sale of fixed assets</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_GainLossOnSaleOfPropertyPlantEquipment" xml:lang="en-US">Gain (Loss) on Disposition of Property Plant Equipment</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_GainLossOnSaleOfPropertyPlantEquipment" xlink:to="label_us-gaap_GainLossOnSaleOfPropertyPlantEquipment"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_OperatingLeasePayment" xlink:label="locator_sfst_OperatingLeasePayment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_OperatingLeasePayment" xml:lang="en-US">Net change in operating leases</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_OperatingLeasePayment" xml:lang="en-US">Amount of cash outflow from operating lease, excluding payments to bring another asset to condition and location necessary for its intended use.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_OperatingLeasePayment" xlink:to="label_sfst_OperatingLeasePayment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="locator_us-gaap_ShareBasedCompensation"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ShareBasedCompensation" xml:lang="en-US">Compensation expense related to stock options and restricted stock grants</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ShareBasedCompensation" xlink:to="label_us-gaap_ShareBasedCompensation"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainLossOnSalesOfLoansNet" xlink:label="locator_us-gaap_GainLossOnSalesOfLoansNet"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_GainLossOnSalesOfLoansNet" xml:lang="en-US">Gain on sale of loans held for sale</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_GainLossOnSalesOfLoansNet" xml:lang="en-US">Gain (Loss) on Sales of Loans, Net</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_GainLossOnSalesOfLoansNet" xlink:to="label_us-gaap_GainLossOnSalesOfLoansNet"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale" xlink:label="locator_us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale" xml:lang="en-US">Loans originated and held for sale</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale" xml:lang="en-US">Payments for Origination and Purchases of Loans Held-for-sale</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale" xlink:to="label_us-gaap_PaymentsForOriginationAndPurchasesOfLoansHeldForSale"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfLoansHeldForSale" xlink:label="locator_us-gaap_ProceedsFromSaleOfLoansHeldForSale"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProceedsFromSaleOfLoansHeldForSale" xml:lang="en-US">Proceeds from sale of loans held for sale</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProceedsFromSaleOfLoansHeldForSale" xlink:to="label_us-gaap_ProceedsFromSaleOfLoansHeldForSale"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInDeferredIncomeTaxes" xlink:label="locator_us-gaap_IncreaseDecreaseInDeferredIncomeTaxes"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_IncreaseDecreaseInDeferredIncomeTaxes" xml:lang="en-US">Decrease (increase) in deferred tax asset</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IncreaseDecreaseInDeferredIncomeTaxes" xml:lang="en-US">Increase (Decrease) in Deferred Income Taxes</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IncreaseDecreaseInDeferredIncomeTaxes" xlink:to="label_us-gaap_IncreaseDecreaseInDeferredIncomeTaxes"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:label="locator_us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xml:lang="en-US">Decrease (increase) in other assets</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xml:lang="en-US">Increase (Decrease) in Other Operating Assets</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:to="label_us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:label="locator_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xml:lang="en-US">Decrease in other liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:to="label_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="locator_us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_NetCashProvidedByUsedInOperatingActivities" xml:lang="en-US">Net cash provided by (used for) operating activities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NetCashProvidedByUsedInOperatingActivities" xml:lang="en-US">Net Cash Provided by (Used in) Operating Activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:to="label_us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:label="locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xml:lang="en-US">Investing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract" xlink:to="label_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_IncreaseDecreaseInCashRealizedInvestingActivitiesAbstract" xlink:label="locator_sfst_IncreaseDecreaseInCashRealizedInvestingActivitiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_IncreaseDecreaseInCashRealizedInvestingActivitiesAbstract" xml:lang="en-US">Increase (decrease) in cash realized from:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_IncreaseDecreaseInCashRealizedInvestingActivitiesAbstract" xlink:to="label_sfst_IncreaseDecreaseInCashRealizedInvestingActivitiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsForProceedsFromLoansAndLeases" xlink:label="locator_us-gaap_PaymentsForProceedsFromLoansAndLeases"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_PaymentsForProceedsFromLoansAndLeases" xml:lang="en-US">Increase in loans, net</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PaymentsForProceedsFromLoansAndLeases" xml:lang="en-US">Payments for (Proceeds from) Loans and Leases</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PaymentsForProceedsFromLoansAndLeases" xlink:to="label_us-gaap_PaymentsForProceedsFromLoansAndLeases"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="locator_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xml:lang="en-US">Purchase of property and equipment</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xml:lang="en-US">Payments to Acquire Property, Plant, and Equipment</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:to="label_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_PaymentToAcquireMarketableSecuritiesAbstract" xlink:label="locator_sfst_PaymentToAcquireMarketableSecuritiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_PaymentToAcquireMarketableSecuritiesAbstract" xml:lang="en-US">Purchase of investment securities:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_PaymentToAcquireMarketableSecuritiesAbstract" xlink:to="label_sfst_PaymentToAcquireMarketableSecuritiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecurities" xlink:label="locator_us-gaap_PaymentsToAcquireAvailableForSaleSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_PaymentsToAcquireAvailableForSaleSecurities" xml:lang="en-US">Available for sale</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PaymentsToAcquireAvailableForSaleSecurities" xml:lang="en-US">Payments to Acquire Available-for-sale Securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PaymentsToAcquireAvailableForSaleSecurities" xlink:to="label_us-gaap_PaymentsToAcquireAvailableForSaleSecurities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireOtherInvestments" xlink:label="locator_us-gaap_PaymentsToAcquireOtherInvestments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_PaymentsToAcquireOtherInvestments" xml:lang="en-US">Other</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PaymentsToAcquireOtherInvestments" xml:lang="en-US">Payments to Acquire Other Investments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PaymentsToAcquireOtherInvestments" xlink:to="label_us-gaap_PaymentsToAcquireOtherInvestments"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ProceedsFromMaturitiesCallsAndRepaymentsOfInvestmentSecuritiesAbstract" xlink:label="locator_sfst_ProceedsFromMaturitiesCallsAndRepaymentsOfInvestmentSecuritiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ProceedsFromMaturitiesCallsAndRepaymentsOfInvestmentSecuritiesAbstract" xml:lang="en-US">Payments and maturities, calls and repayments of investment securities:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ProceedsFromMaturitiesCallsAndRepaymentsOfInvestmentSecuritiesAbstract" xlink:to="label_sfst_ProceedsFromMaturitiesCallsAndRepaymentsOfInvestmentSecuritiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xlink:label="locator_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xml:lang="en-US">Available for sale</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xlink:to="label_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfOtherInvestments" xlink:label="locator_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfOtherInvestments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfOtherInvestments" xml:lang="en-US">Other investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfOtherInvestments" xml:lang="en-US">Proceeds from Maturities, Prepayments and Calls of Other Investments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfOtherInvestments" xlink:to="label_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfOtherInvestments"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireLifeInsurancePolicies" xlink:label="locator_us-gaap_PaymentsToAcquireLifeInsurancePolicies"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_PaymentsToAcquireLifeInsurancePolicies" xml:lang="en-US">Purchase of bank owned life insurance</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PaymentsToAcquireLifeInsurancePolicies" xml:lang="en-US">Payment to Acquire Life Insurance Policy, Investing Activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PaymentsToAcquireLifeInsurancePolicies" xlink:to="label_us-gaap_PaymentsToAcquireLifeInsurancePolicies"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:label="locator_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xml:lang="en-US">Proceeds from sale of fixed assets</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:to="label_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfWhollyOwnedRealEstateAndRealEstateAcquiredInSettlementOfLoans" xlink:label="locator_us-gaap_ProceedsFromSaleOfWhollyOwnedRealEstateAndRealEstateAcquiredInSettlementOfLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProceedsFromSaleOfWhollyOwnedRealEstateAndRealEstateAcquiredInSettlementOfLoans" xml:lang="en-US">Proceeds from sale of other real estate owned</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProceedsFromSaleOfWhollyOwnedRealEstateAndRealEstateAcquiredInSettlementOfLoans" xlink:to="label_us-gaap_ProceedsFromSaleOfWhollyOwnedRealEstateAndRealEstateAcquiredInSettlementOfLoans"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="locator_us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_NetCashProvidedByUsedInInvestingActivities" xml:lang="en-US">Net cash used for investing activities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NetCashProvidedByUsedInInvestingActivities" xml:lang="en-US">Net Cash Provided by (Used in) Investing Activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:to="label_us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:label="locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xml:lang="en-US">Financing activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract" xlink:to="label_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_IncreaseDecreaseInCashRealizedFinancingActivitiesAbstract" xlink:label="locator_sfst_IncreaseDecreaseInCashRealizedFinancingActivitiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_sfst_IncreaseDecreaseInCashRealizedFinancingActivitiesAbstract" xml:lang="en-US">Increase (decrease) in cash realized from:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_IncreaseDecreaseInCashRealizedFinancingActivitiesAbstract" xlink:to="label_sfst_IncreaseDecreaseInCashRealizedFinancingActivitiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInDeposits" xlink:label="locator_us-gaap_IncreaseDecreaseInDeposits"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IncreaseDecreaseInDeposits" xml:lang="en-US">Increase in deposits, net</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IncreaseDecreaseInDeposits" xlink:to="label_us-gaap_IncreaseDecreaseInDeposits"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_DecreaseInFederalHomeLoanBankAdvancesAndOtherBorrowings" xlink:label="locator_sfst_DecreaseInFederalHomeLoanBankAdvancesAndOtherBorrowings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_sfst_DecreaseInFederalHomeLoanBankAdvancesAndOtherBorrowings" xml:lang="en-US">Decrease in Federal Home Loan Bank advances and other borrowings, net</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_DecreaseInFederalHomeLoanBankAdvancesAndOtherBorrowings" xml:lang="en-US">Decrease in federal home loan bank advances and other borrowings.</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_DecreaseInFederalHomeLoanBankAdvancesAndOtherBorrowings" xml:lang="en-US">Decrease In Federal Home Loan Bank Advances And Other Borrowings</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_DecreaseInFederalHomeLoanBankAdvancesAndOtherBorrowings" xlink:to="label_sfst_DecreaseInFederalHomeLoanBankAdvancesAndOtherBorrowings"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromStockOptionsExercised" xlink:label="locator_us-gaap_ProceedsFromStockOptionsExercised"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProceedsFromStockOptionsExercised" xml:lang="en-US">Proceeds from the exercise of stock options</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProceedsFromStockOptionsExercised" xlink:to="label_us-gaap_ProceedsFromStockOptionsExercised"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="locator_us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_NetCashProvidedByUsedInFinancingActivities" xml:lang="en-US">Net cash provided by financing activities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NetCashProvidedByUsedInFinancingActivities" xml:lang="en-US">Net Cash Provided by (Used in) Financing Activities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:to="label_us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:label="locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xml:lang="en-US">Net increase in cash and cash equivalents</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xml:lang="en-US">Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect" xlink:to="label_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseExcludingExchangeRateEffect"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="locator_us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="label_us-gaap_CashAndCashEquivalentsAtCarryingValue" xml:lang="en-US">Cash and cash equivalents at beginning of the period</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="label_us-gaap_CashAndCashEquivalentsAtCarryingValue" xml:lang="en-US">Cash and cash equivalents at end of the period</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CashAndCashEquivalentsAtCarryingValue" xml:lang="en-US">Cash and Cash Equivalents, at Carrying Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:to="label_us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract" xlink:label="locator_us-gaap_SupplementalCashFlowInformationAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SupplementalCashFlowInformationAbstract" xml:lang="en-US">Supplemental information</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SupplementalCashFlowInformationAbstract" xlink:to="label_us-gaap_SupplementalCashFlowInformationAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_CashPaidAbstract" xlink:label="locator_sfst_CashPaidAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_CashPaidAbstract" xml:lang="en-US">Cash paid for</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_CashPaidAbstract" xlink:to="label_sfst_CashPaidAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestPaidNet" xlink:label="locator_us-gaap_InterestPaidNet"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestPaidNet" xml:lang="en-US">Interest</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestPaidNet" xlink:to="label_us-gaap_InterestPaidNet"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxesPaid" xlink:label="locator_us-gaap_IncomeTaxesPaid"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IncomeTaxesPaid" xml:lang="en-US">Income taxes</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IncomeTaxesPaid" xlink:to="label_us-gaap_IncomeTaxesPaid"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:label="locator_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xml:lang="en-US">Schedule of non-cash transactions</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract" xlink:to="label_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ForeclosureOfOtherRealEstate" xlink:label="locator_sfst_ForeclosureOfOtherRealEstate"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ForeclosureOfOtherRealEstate" xml:lang="en-US">Foreclosure of other real estate</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ForeclosureOfOtherRealEstate" xml:lang="en-US">Foreclosure of other real estate</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ForeclosureOfOtherRealEstate" xlink:to="label_sfst_ForeclosureOfOtherRealEstate"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_UnrealizedGainLossOnSecuritiesNetOfIncomeTaxes" xlink:label="locator_sfst_UnrealizedGainLossOnSecuritiesNetOfIncomeTaxes"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_UnrealizedGainLossOnSecuritiesNetOfIncomeTaxes" xml:lang="en-US">Unrealized gain (loss) on securities, net of income taxes</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_UnrealizedGainLossOnSecuritiesNetOfIncomeTaxes" xml:lang="en-US">Noncash is defined as information about all investing and financing activities of an enterprise during a period that affect recognized assets or liabilities but that do not result in cash receipts or cash payments in the period. "Part noncash" refers to that portion of the transaction not resulting in cash receipts or cash payments in the period.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_UnrealizedGainLossOnSecuritiesNetOfIncomeTaxes" xlink:to="label_sfst_UnrealizedGainLossOnSecuritiesNetOfIncomeTaxes"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_RightOfUseAssetsObtainedInExchangeForLeaseObligationsAbstract" xlink:label="locator_sfst_RightOfUseAssetsObtainedInExchangeForLeaseObligationsAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_RightOfUseAssetsObtainedInExchangeForLeaseObligationsAbstract" xml:lang="en-US">Right-of-use assets obtained in exchange for lease obligations:</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_RightOfUseAssetsObtainedInExchangeForLeaseObligationsAbstract" xml:lang="en-US">Right of use assets obtained in exchange for lease obligations.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_RightOfUseAssetsObtainedInExchangeForLeaseObligationsAbstract" xlink:to="label_sfst_RightOfUseAssetsObtainedInExchangeForLeaseObligationsAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_OperatingLeases" xlink:label="locator_sfst_OperatingLeases"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_OperatingLeases" xml:lang="en-US">Operating leases</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_OperatingLeases" xml:lang="en-US">Operating leases.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_OperatingLeases" xlink:to="label_sfst_OperatingLeases"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract" xlink:label="locator_us-gaap_AccountingPoliciesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AccountingPoliciesAbstract" xml:lang="en-US">Accounting Policies [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AccountingPoliciesAbstract" xlink:to="label_us-gaap_AccountingPoliciesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationBasisOfPresentationBusinessDescriptionAndAccountingPoliciesTextBlock" xlink:label="locator_us-gaap_OrganizationConsolidationBasisOfPresentationBusinessDescriptionAndAccountingPoliciesTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OrganizationConsolidationBasisOfPresentationBusinessDescriptionAndAccountingPoliciesTextBlock" xml:lang="en-US">Nature of Business and Basis of Presentation</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OrganizationConsolidationBasisOfPresentationBusinessDescriptionAndAccountingPoliciesTextBlock" xlink:to="label_us-gaap_OrganizationConsolidationBasisOfPresentationBusinessDescriptionAndAccountingPoliciesTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:label="locator_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xml:lang="en-US">Investments, Debt and Equity Securities [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract" xlink:to="label_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" xlink:label="locator_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" xml:lang="en-US">Investment Securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock" xlink:to="label_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_MortgageLoansHeldForSaleAbstract" xlink:label="locator_sfst_MortgageLoansHeldForSaleAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_MortgageLoansHeldForSaleAbstract" xml:lang="en-US">Mortgage Loans Held for Sale [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_MortgageLoansHeldForSaleAbstract" xlink:to="label_sfst_MortgageLoansHeldForSaleAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_MortgageLoansHeldForSaleTextBlock" xlink:label="locator_sfst_MortgageLoansHeldForSaleTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_MortgageLoansHeldForSaleTextBlock" xml:lang="en-US">Mortgage Loans Held for Sale</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_MortgageLoansHeldForSaleTextBlock" xml:lang="en-US">The entire disclosure for mortgage loans held for sale.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_MortgageLoansHeldForSaleTextBlock" xlink:to="label_sfst_MortgageLoansHeldForSaleTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsNotesLoansAndFinancingReceivableGrossAllowanceAndNetAbstract" xlink:label="locator_us-gaap_AccountsNotesLoansAndFinancingReceivableGrossAllowanceAndNetAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AccountsNotesLoansAndFinancingReceivableGrossAllowanceAndNetAbstract" xml:lang="en-US">Accounts, Notes, Loans and Financing Receivable, Gross, Allowance, and Net [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AccountsNotesLoansAndFinancingReceivableGrossAllowanceAndNetAbstract" xlink:to="label_us-gaap_AccountsNotesLoansAndFinancingReceivableGrossAllowanceAndNetAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock" xlink:label="locator_us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock" xml:lang="en-US">Loans and Allowance for Loan Losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock" xlink:to="label_us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_TroubledDebtRestructuringsAbstract" xlink:label="locator_sfst_TroubledDebtRestructuringsAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_TroubledDebtRestructuringsAbstract" xml:lang="en-US">Troubled Debt Restructurings [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_TroubledDebtRestructuringsAbstract" xlink:to="label_sfst_TroubledDebtRestructuringsAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_TroubledDebtRestructuringTextBlock" xlink:label="locator_sfst_TroubledDebtRestructuringTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_TroubledDebtRestructuringTextBlock" xml:lang="en-US">Troubled Debt Restructurings</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_TroubledDebtRestructuringTextBlock" xml:lang="en-US">Disclosure of the accounting policy for loan agreements whose terms have been modified because of the inability of the borrower for financial reasons to comply with the terms of the original loan agreement. A creditor discloses material facts pertaining to significant modifications.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_TroubledDebtRestructuringTextBlock" xlink:to="label_sfst_TroubledDebtRestructuringTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:label="locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xml:lang="en-US">Derivative Instruments and Hedging Activities Disclosure [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract" xlink:to="label_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:label="locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xml:lang="en-US">Derivative Financial Instruments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock" xlink:to="label_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosureTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract" xlink:label="locator_us-gaap_FairValueDisclosuresAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueDisclosuresAbstract" xml:lang="en-US">Fair Value Disclosures [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueDisclosuresAbstract" xlink:to="label_us-gaap_FairValueDisclosuresAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock" xlink:label="locator_us-gaap_FairValueDisclosuresTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueDisclosuresTextBlock" xml:lang="en-US">Fair Value Accounting</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueDisclosuresTextBlock" xlink:to="label_us-gaap_FairValueDisclosuresTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract" xlink:label="locator_us-gaap_LeasesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LeasesAbstract" xml:lang="en-US">Leases [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LeasesAbstract" xlink:to="label_us-gaap_LeasesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeasesTextBlock" xlink:label="locator_us-gaap_LesseeOperatingLeasesTextBlock"/>
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    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareTextBlock" xlink:label="locator_us-gaap_EarningsPerShareTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_EarningsPerShareTextBlock" xml:lang="en-US">Earnings Per Common Share</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_EarningsPerShareTextBlock" xlink:to="label_us-gaap_EarningsPerShareTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingAbstract" xlink:label="locator_us-gaap_SegmentReportingAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SegmentReportingAbstract" xml:lang="en-US">Segment Reporting [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SegmentReportingAbstract" xlink:to="label_us-gaap_SegmentReportingAbstract"/>
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    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SegmentReportingDisclosureTextBlock" xml:lang="en-US">Reportable Segments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SegmentReportingDisclosureTextBlock" xlink:to="label_us-gaap_SegmentReportingDisclosureTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_BusinessActivityPolicyTextBlock" xlink:label="locator_sfst_BusinessActivityPolicyTextBlock"/>
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    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_BusinessActivityPolicyTextBlock" xml:lang="en-US">Business activity.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_BusinessActivityPolicyTextBlock" xlink:to="label_sfst_BusinessActivityPolicyTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:label="locator_us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
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    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_BasisOfAccountingPolicyPolicyTextBlock" xlink:to="label_us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock" xlink:label="locator_us-gaap_SegmentReportingPolicyPolicyTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SegmentReportingPolicyPolicyTextBlock" xml:lang="en-US">Business Segments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SegmentReportingPolicyPolicyTextBlock" xlink:to="label_us-gaap_SegmentReportingPolicyPolicyTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_UseOfEstimates" xlink:label="locator_us-gaap_UseOfEstimates"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_UseOfEstimates" xml:lang="en-US">Use of Estimates</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_UseOfEstimates" xlink:to="label_us-gaap_UseOfEstimates"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConcentrationRiskCreditRisk" xlink:label="locator_us-gaap_ConcentrationRiskCreditRisk"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ConcentrationRiskCreditRisk" xml:lang="en-US">Risks and Uncertainties</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ConcentrationRiskCreditRisk" xlink:to="label_us-gaap_ConcentrationRiskCreditRisk"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PriorPeriodReclassificationAdjustmentDescription" xlink:label="locator_us-gaap_PriorPeriodReclassificationAdjustmentDescription"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PriorPeriodReclassificationAdjustmentDescription" xml:lang="en-US">Reclassifications</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PriorPeriodReclassificationAdjustmentDescription" xlink:to="label_us-gaap_PriorPeriodReclassificationAdjustmentDescription"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsequentEventsPolicyPolicyTextBlock" xlink:label="locator_us-gaap_SubsequentEventsPolicyPolicyTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SubsequentEventsPolicyPolicyTextBlock" xml:lang="en-US">Subsequent Events</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SubsequentEventsPolicyPolicyTextBlock" xlink:to="label_us-gaap_SubsequentEventsPolicyPolicyTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_EffectiveAccountingStandardsNewlyIssuedPolicyTextBlock" xlink:label="locator_sfst_EffectiveAccountingStandardsNewlyIssuedPolicyTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_EffectiveAccountingStandardsNewlyIssuedPolicyTextBlock" xml:lang="en-US">Newly Issued, But Not Yet Effective Accounting Standards</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_EffectiveAccountingStandardsNewlyIssuedPolicyTextBlock" xml:lang="en-US">Effective accounting standards newly issued policy text block.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_EffectiveAccountingStandardsNewlyIssuedPolicyTextBlock" xlink:to="label_sfst_EffectiveAccountingStandardsNewlyIssuedPolicyTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesReconciliationTableTextBlock" xlink:label="locator_us-gaap_ScheduleOfAvailableForSaleSecuritiesReconciliationTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfAvailableForSaleSecuritiesReconciliationTableTextBlock" xml:lang="en-US">Schedule of Amortized Costs and Fair Value of Investment Securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfAvailableForSaleSecuritiesReconciliationTableTextBlock" xlink:to="label_us-gaap_ScheduleOfAvailableForSaleSecuritiesReconciliationTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:label="locator_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xml:lang="en-US">Schedule of Fair Values Investment Securities Available for Contractual Maturities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock" xlink:to="label_us-gaap_InvestmentsClassifiedByContractualMaturityDateTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfUnrealizedLossOnInvestmentsTableTextBlock" xlink:label="locator_us-gaap_ScheduleOfUnrealizedLossOnInvestmentsTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfUnrealizedLossOnInvestmentsTableTextBlock" xml:lang="en-US">Schedule of Gross Unrealized Losses on Investment Securities and Fair Market Value of Related Securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfUnrealizedLossOnInvestmentsTableTextBlock" xlink:to="label_us-gaap_ScheduleOfUnrealizedLossOnInvestmentsTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfOtherInvestmentsNotReadilyMarketableTextBlock" xlink:label="locator_us-gaap_ScheduleOfOtherInvestmentsNotReadilyMarketableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfOtherInvestmentsNotReadilyMarketableTextBlock" xml:lang="en-US">Schedule of Other Investments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfOtherInvestmentsNotReadilyMarketableTextBlock" xlink:to="label_us-gaap_ScheduleOfOtherInvestmentsNotReadilyMarketableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFinancingReceivablesPastDueTable" xlink:label="locator_us-gaap_ScheduleOfFinancingReceivablesPastDueTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfFinancingReceivablesPastDueTable" xml:lang="en-US">Financing Receivable, Past Due [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfFinancingReceivablesPastDueTable" xlink:to="label_us-gaap_ScheduleOfFinancingReceivablesPastDueTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis" xlink:label="locator_us-gaap_FinancialInstrumentAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancialInstrumentAxis" xml:lang="en-US">Financial Instrument [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancialInstrumentAxis" xlink:to="label_us-gaap_FinancialInstrumentAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConsumerLoanMember" xlink:label="locator_us-gaap_ConsumerLoanMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ConsumerLoanMember" xml:lang="en-US">Consumer Loan [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ConsumerLoanMember" xlink:to="label_us-gaap_ConsumerLoanMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommercialLoanMember" xlink:label="locator_us-gaap_CommercialLoanMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CommercialLoanMember" xml:lang="en-US">Commercial Loan [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CommercialLoanMember" xlink:to="label_us-gaap_CommercialLoanMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems" xlink:label="locator_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems" xlink:to="label_us-gaap_FinancingReceivableAllowanceForCreditLossesLineItems"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock" xlink:label="locator_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock" xml:lang="en-US">Schedule of Composition of Loan Portfolio</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock" xlink:to="label_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoanMaturityDistributionByTypeAndRelatedInterestRateTableTextBlock" xlink:label="locator_sfst_LoanMaturityDistributionByTypeAndRelatedInterestRateTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoanMaturityDistributionByTypeAndRelatedInterestRateTableTextBlock" xml:lang="en-US">Schedule of Loan Maturity Distribution by Type and Related Interest Rate</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoanMaturityDistributionByTypeAndRelatedInterestRateTableTextBlock" xml:lang="en-US">Tabular disclosure of loan maturity distribution by type.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoanMaturityDistributionByTypeAndRelatedInterestRateTableTextBlock" xlink:to="label_sfst_LoanMaturityDistributionByTypeAndRelatedInterestRateTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_OutstandingLoansByRiskCategoryTableTextBlock" xlink:label="locator_sfst_OutstandingLoansByRiskCategoryTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_OutstandingLoansByRiskCategoryTableTextBlock" xml:lang="en-US">Summary of breakdown of outstanding loans by risk category</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_OutstandingLoansByRiskCategoryTableTextBlock" xml:lang="en-US">Outstanding commercial and consumer loans by risk category.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_OutstandingLoansByRiskCategoryTableTextBlock" xlink:to="label_sfst_OutstandingLoansByRiskCategoryTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PastDueFinancingReceivablesTableTextBlock" xlink:label="locator_us-gaap_PastDueFinancingReceivablesTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PastDueFinancingReceivablesTableTextBlock" xml:lang="en-US">Summary of outstanding commercial and consumer loans which include loans on nonaccrual by past due status</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PastDueFinancingReceivablesTableTextBlock" xlink:to="label_us-gaap_PastDueFinancingReceivablesTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFinancingReceivablesNonAccrualStatusTableTextBlock" xlink:label="locator_us-gaap_ScheduleOfFinancingReceivablesNonAccrualStatusTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfFinancingReceivablesNonAccrualStatusTableTextBlock" xml:lang="en-US">Schedule of Nonperforming Assets, Including Nonaccruing TDRs</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfFinancingReceivablesNonAccrualStatusTableTextBlock" xlink:to="label_us-gaap_ScheduleOfFinancingReceivablesNonAccrualStatusTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivablesTableTextBlock" xlink:label="locator_us-gaap_ImpairedFinancingReceivablesTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivablesTableTextBlock" xml:lang="en-US">Schedule of Key Information for Impaired Loans</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivablesTableTextBlock" xlink:to="label_us-gaap_ImpairedFinancingReceivablesTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SummaryOfAverageRecordedInvestmentInImpairedLoansAndAmountOfInterestIncomeTableTextBlock" xlink:label="locator_sfst_SummaryOfAverageRecordedInvestmentInImpairedLoansAndAmountOfInterestIncomeTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SummaryOfAverageRecordedInvestmentInImpairedLoansAndAmountOfInterestIncomeTableTextBlock" xml:lang="en-US">Schedule of Average Recorded Investment and Interest Income Recognized on Impaired Loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_SummaryOfAverageRecordedInvestmentInImpairedLoansAndAmountOfInterestIncomeTableTextBlock" xml:lang="en-US">Summary of average recorded investment in impaired loans and the amount of interest income.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SummaryOfAverageRecordedInvestmentInImpairedLoansAndAmountOfInterestIncomeTableTextBlock" xlink:to="label_sfst_SummaryOfAverageRecordedInvestmentInImpairedLoansAndAmountOfInterestIncomeTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SummaryOfAllowanceForLoanLossesByCommercialAndConsumerPortfolioSegmentsTableTextBlock" xlink:label="locator_sfst_SummaryOfAllowanceForLoanLossesByCommercialAndConsumerPortfolioSegmentsTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SummaryOfAllowanceForLoanLossesByCommercialAndConsumerPortfolioSegmentsTableTextBlock" xml:lang="en-US">Schedule of Allowance for Loan Losses by Commercial and Consumer Portfolio Segments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_SummaryOfAllowanceForLoanLossesByCommercialAndConsumerPortfolioSegmentsTableTextBlock" xml:lang="en-US">Summary of allowance for loan losses by commercial and consumer portfolio segments.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SummaryOfAllowanceForLoanLossesByCommercialAndConsumerPortfolioSegmentsTableTextBlock" xlink:to="label_sfst_SummaryOfAllowanceForLoanLossesByCommercialAndConsumerPortfolioSegmentsTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ImpairmentMethodologyForCreditLossesOnFinancingReceivablesTableTextBlock" xlink:label="locator_sfst_ImpairmentMethodologyForCreditLossesOnFinancingReceivablesTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ImpairmentMethodologyForCreditLossesOnFinancingReceivablesTableTextBlock" xml:lang="en-US">Schedule of Allowance for Loan Losses and Recorded Investment in Loans by Impairment</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ImpairmentMethodologyForCreditLossesOnFinancingReceivablesTableTextBlock" xml:lang="en-US">Impairment methodology for credit losses on financing receivables.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ImpairmentMethodologyForCreditLossesOnFinancingReceivablesTableTextBlock" xlink:to="label_sfst_ImpairmentMethodologyForCreditLossesOnFinancingReceivablesTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TroubledDebtRestructuringsOnFinancingReceivablesTableTextBlock" xlink:label="locator_us-gaap_TroubledDebtRestructuringsOnFinancingReceivablesTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_TroubledDebtRestructuringsOnFinancingReceivablesTableTextBlock" xml:lang="en-US">Schedule of Concession at the Time of Modification and the Recorded Investment In Our Tdrs Before and After Their Modification</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_TroubledDebtRestructuringsOnFinancingReceivablesTableTextBlock" xlink:to="label_us-gaap_TroubledDebtRestructuringsOnFinancingReceivablesTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock" xlink:label="locator_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock" xml:lang="en-US">Schedule of Outstanding Financial Derivative Instruments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock" xlink:to="label_us-gaap_ScheduleOfNotionalAmountsOfOutstandingDerivativePositionsTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:label="locator_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xml:lang="en-US">Schedule of Assets And Liabilities Measured at Fair Value on Recurring Basis</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock" xlink:to="label_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock" xlink:label="locator_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock" xml:lang="en-US">Schedule of Assets And Liabilities Measured at Fair Value on Nonrecurring Basis</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock" xlink:to="label_us-gaap_FairValueAssetsMeasuredOnNonrecurringBasisTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByBalanceSheetGroupingTextBlock" xlink:label="locator_us-gaap_FairValueByBalanceSheetGroupingTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueByBalanceSheetGroupingTextBlock" xml:lang="en-US">Schedule of Estimated Fair Values of the Company's Financial Instruments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueByBalanceSheetGroupingTextBlock" xlink:to="label_us-gaap_FairValueByBalanceSheetGroupingTextBlock"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_MaturitiesOfLeaseLiabilitiesTableTextBlock" xlink:label="locator_sfst_MaturitiesOfLeaseLiabilitiesTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_MaturitiesOfLeaseLiabilitiesTableTextBlock" xml:lang="en-US">Maturities of lease liabilities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_MaturitiesOfLeaseLiabilitiesTableTextBlock" xml:lang="en-US">Tabular disclosure of Maturities of lease liabilities.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_MaturitiesOfLeaseLiabilitiesTableTextBlock" xlink:to="label_sfst_MaturitiesOfLeaseLiabilitiesTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:label="locator_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xml:lang="en-US">Schedule of Earnings Per Share Calculation</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock" xlink:to="label_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock" xlink:label="locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock" xml:lang="en-US">Schedule of Financial Information for Each Reportable Segment</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock" xlink:to="label_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CreditFacilityAxis" xlink:label="locator_us-gaap_CreditFacilityAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CreditFacilityAxis" xml:lang="en-US">Credit Facility [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CreditFacilityAxis" xlink:to="label_us-gaap_CreditFacilityAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LineOfCreditMember" xlink:label="locator_us-gaap_LineOfCreditMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LineOfCreditMember" xml:lang="en-US">Holding Company Line of Credit [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LineOfCreditMember" xlink:to="label_us-gaap_LineOfCreditMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis" xlink:label="locator_srt_RangeAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_srt_RangeAxis" xml:lang="en-US">Statistical Measurement [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_srt_RangeAxis" xlink:to="label_srt_RangeAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember" xlink:label="locator_srt_MinimumMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_srt_MinimumMember" xml:lang="en-US">Minimum [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_srt_MinimumMember" xlink:to="label_srt_MinimumMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember" xlink:label="locator_srt_MaximumMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_srt_MaximumMember" xml:lang="en-US">Maximum [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_srt_MaximumMember" xlink:to="label_srt_MaximumMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransactionTypeAxis" xlink:label="locator_us-gaap_TransactionTypeAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_TransactionTypeAxis" xml:lang="en-US">Transaction Type [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_TransactionTypeAxis" xlink:to="label_us-gaap_TransactionTypeAxis"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_COVID19PandemicMember" xlink:label="locator_sfst_COVID19PandemicMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_COVID19PandemicMember" xml:lang="en-US">COVID-19 pandemic [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_COVID19PandemicMember" xml:lang="en-US">COVID-19 pandemic [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_COVID19PandemicMember" xlink:to="label_sfst_COVID19PandemicMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_FederalReserveReducedTargetFederalFundsRateBasisPoint" xlink:label="locator_sfst_FederalReserveReducedTargetFederalFundsRateBasisPoint"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_FederalReserveReducedTargetFederalFundsRateBasisPoint" xml:lang="en-US">Federal reserve reduced target federal funds rate basis point</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_FederalReserveReducedTargetFederalFundsRateBasisPoint" xml:lang="en-US">Federal reserve reduced target federal funds rate basis point.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_FederalReserveReducedTargetFederalFundsRateBasisPoint" xlink:to="label_sfst_FederalReserveReducedTargetFederalFundsRateBasisPoint"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:label="locator_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xml:lang="en-US">Line of credit borrowing capacity</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity" xlink:to="label_us-gaap_LineOfCreditFacilityMaximumBorrowingCapacity"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LineOfCredit" xlink:label="locator_us-gaap_LineOfCredit"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LineOfCredit" xml:lang="en-US">Line of credit</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LineOfCredit" xlink:to="label_us-gaap_LineOfCredit"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate" xlink:label="locator_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate" xml:lang="en-US">Federal funds rate</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate" xlink:to="label_us-gaap_EffectiveIncomeTaxRateReconciliationAtFederalStatutoryIncomeTaxRate"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_MarketInterestRates" xlink:label="locator_sfst_MarketInterestRates"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_MarketInterestRates" xml:lang="en-US">Market interest rates</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_MarketInterestRates" xml:lang="en-US">Market interest rates.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_MarketInterestRates" xlink:to="label_sfst_MarketInterestRates"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_InvestmentSecuritiesTextualAbstract" xlink:label="locator_sfst_InvestmentSecuritiesTextualAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_InvestmentSecuritiesTextualAbstract" xml:lang="en-US">Investment Securities (Textual)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_InvestmentSecuritiesTextualAbstract" xml:lang="en-US">Investment securities.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_InvestmentSecuritiesTextualAbstract" xlink:to="label_sfst_InvestmentSecuritiesTextualAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" xlink:label="locator_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" xml:lang="en-US">Sale of investment securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt" xlink:to="label_us-gaap_ProceedsFromSaleOfAvailableForSaleSecuritiesDebt"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossOnSaleOfInvestments" xlink:label="locator_us-gaap_LossOnSaleOfInvestments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LossOnSaleOfInvestments" xml:lang="en-US">Loss on sale of investments securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LossOnSaleOfInvestments" xlink:to="label_us-gaap_LossOnSaleOfInvestments"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GainOnSaleOfInvestments" xlink:label="locator_us-gaap_GainOnSaleOfInvestments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_GainOnSaleOfInvestments" xml:lang="en-US">Gain on sale of investment securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_GainOnSaleOfInvestments" xlink:to="label_us-gaap_GainOnSaleOfInvestments"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionLessThanTwelveMonths" xlink:label="locator_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionLessThanTwelveMonths"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionLessThanTwelveMonths" xml:lang="en-US">Fair market value, less than 12 months, number of investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionLessThanTwelveMonths" xml:lang="en-US">Available for sale Securities, Less than 12 months, Number of investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionLessThanTwelveMonths" xml:lang="en-US">Number of investments in continuous unrealized loss position, less than twelve months.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionLessThanTwelveMonths" xlink:to="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionLessThanTwelveMonths"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionLessThanTwelveMonths" xlink:label="locator_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionLessThanTwelveMonths"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionLessThanTwelveMonths" xml:lang="en-US">Fair market value, less than 12 months</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionLessThanTwelveMonths" xml:lang="en-US">Investments with fair market value in continuous unrealized loss position for less than twelve months.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionLessThanTwelveMonths" xlink:to="label_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionLessThanTwelveMonths"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NumberOfInvestmentInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xlink:label="locator_sfst_NumberOfInvestmentInContinuousUnrealizedLossPositionTwelveMonthsOrLonger"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NumberOfInvestmentInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xml:lang="en-US">Fair market value, 12 months or longer, number of investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NumberOfInvestmentInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xml:lang="en-US">Number of investment in continuous unrealized loss position twelve months or longer.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NumberOfInvestmentInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xlink:to="label_sfst_NumberOfInvestmentInContinuousUnrealizedLossPositionTwelveMonthsOrLonger"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xlink:label="locator_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionTwelveMonthsOrLonger"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xml:lang="en-US">Fair market value, 12 months or longer</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xml:lang="en-US">Investments with fair market value In continuous unrealized loss position twelve months or longer.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xlink:to="label_sfst_InvestmentsWithFairMarketValueInContinuousUnrealizedLossPositionTwelveMonthsOrLonger"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleRestricted" xlink:label="locator_us-gaap_DebtSecuritiesAvailableForSaleRestricted"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DebtSecuritiesAvailableForSaleRestricted" xml:lang="en-US">Securities pledged as collateral for repurchase agreements from brokers</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DebtSecuritiesAvailableForSaleRestricted" xlink:to="label_us-gaap_DebtSecuritiesAvailableForSaleRestricted"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SecuritiesPledgedToSecureClientDeposit" xlink:label="locator_sfst_SecuritiesPledgedToSecureClientDeposit"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SecuritiesPledgedToSecureClientDeposit" xml:lang="en-US">Securities pledged to secure client deposit</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_SecuritiesPledgedToSecureClientDeposit" xml:lang="en-US">Securities pledged to secure client deposit.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SecuritiesPledgedToSecureClientDeposit" xlink:to="label_sfst_SecuritiesPledgedToSecureClientDeposit"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xlink:label="locator_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xml:lang="en-US">Schedule of Available-for-sale Securities [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable" xlink:to="label_us-gaap_ScheduleOfAvailableForSaleSecuritiesTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasurySecuritiesMember" xlink:label="locator_us-gaap_USTreasurySecuritiesMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_USTreasurySecuritiesMember" xml:lang="en-US">US treasuries [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_USTreasurySecuritiesMember" xlink:to="label_us-gaap_USTreasurySecuritiesMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AgencySecuritiesMember" xlink:label="locator_us-gaap_AgencySecuritiesMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AgencySecuritiesMember" xml:lang="en-US">US Government Agencies [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AgencySecuritiesMember" xlink:to="label_us-gaap_AgencySecuritiesMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SbaSecuritiesMember" xlink:label="locator_sfst_SbaSecuritiesMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SbaSecuritiesMember" xml:lang="en-US">SBA Securities [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_SbaSecuritiesMember" xml:lang="en-US">Sbs securities.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SbaSecuritiesMember" xlink:to="label_sfst_SbaSecuritiesMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USStatesAndPoliticalSubdivisionsMember" xlink:label="locator_us-gaap_USStatesAndPoliticalSubdivisionsMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_USStatesAndPoliticalSubdivisionsMember" xml:lang="en-US">State and Political Subdivisions [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_USStatesAndPoliticalSubdivisionsMember" xlink:to="label_us-gaap_USStatesAndPoliticalSubdivisionsMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetBackedSecuritiesMember" xlink:label="locator_us-gaap_AssetBackedSecuritiesMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AssetBackedSecuritiesMember" xml:lang="en-US">Asset-backed Securities [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AssetBackedSecuritiesMember" xlink:to="label_us-gaap_AssetBackedSecuritiesMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MortgageBackedSecuritiesMember" xlink:label="locator_us-gaap_MortgageBackedSecuritiesMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_MortgageBackedSecuritiesMember" xml:lang="en-US">Mortgage Backed Securities [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_MortgageBackedSecuritiesMember" xlink:to="label_us-gaap_MortgageBackedSecuritiesMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentTypeAxis" xlink:label="locator_us-gaap_InvestmentTypeAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InvestmentTypeAxis" xml:lang="en-US">Investment Type [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InvestmentTypeAxis" xlink:to="label_us-gaap_InvestmentTypeAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FederalHomeLoanMortgageCorporationCertificatesAndObligationsFHLMCMember" xlink:label="locator_us-gaap_FederalHomeLoanMortgageCorporationCertificatesAndObligationsFHLMCMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FederalHomeLoanMortgageCorporationCertificatesAndObligationsFHLMCMember" xml:lang="en-US">FHLMC [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FederalHomeLoanMortgageCorporationCertificatesAndObligationsFHLMCMember" xlink:to="label_us-gaap_FederalHomeLoanMortgageCorporationCertificatesAndObligationsFHLMCMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FederalNationalMortgageAssociationCertificatesAndObligationsFNMAMember" xlink:label="locator_us-gaap_FederalNationalMortgageAssociationCertificatesAndObligationsFNMAMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FederalNationalMortgageAssociationCertificatesAndObligationsFNMAMember" xml:lang="en-US">FNMA [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FederalNationalMortgageAssociationCertificatesAndObligationsFNMAMember" xlink:to="label_us-gaap_FederalNationalMortgageAssociationCertificatesAndObligationsFNMAMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GovernmentNationalMortgageAssociationCertificatesAndObligationsGNMAMember" xlink:label="locator_us-gaap_GovernmentNationalMortgageAssociationCertificatesAndObligationsGNMAMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_GovernmentNationalMortgageAssociationCertificatesAndObligationsGNMAMember" xml:lang="en-US">GNMA [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_GovernmentNationalMortgageAssociationCertificatesAndObligationsGNMAMember" xlink:to="label_us-gaap_GovernmentNationalMortgageAssociationCertificatesAndObligationsGNMAMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:label="locator_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xml:lang="en-US">Debt Securities, Available-for-sale [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems" xlink:to="label_us-gaap_ScheduleOfAvailableForSaleSecuritiesLineItems"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SecuritiesAvailableForSaleMajorCategoriesAbstract" xlink:label="locator_sfst_SecuritiesAvailableForSaleMajorCategoriesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SecuritiesAvailableForSaleMajorCategoriesAbstract" xml:lang="en-US">Amortized costs and fair value of investment securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SecuritiesAvailableForSaleMajorCategoriesAbstract" xlink:to="label_sfst_SecuritiesAvailableForSaleMajorCategoriesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAbstract" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_AvailableForSaleSecuritiesAbstract" xml:lang="en-US">Available for sale</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesAbstract" xlink:to="label_us-gaap_AvailableForSaleSecuritiesAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xml:lang="en-US">Available-for-sale securities, investment securities, Fair Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesDebtSecurities" xlink:to="label_us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xml:lang="en-US">Total investment securities available for sale, Gross Unrealized Gains</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax" xlink:to="label_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xml:lang="en-US">Total investment securities available for sale, Gross Unrealized Losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax" xlink:to="label_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAmortizedCost" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesAmortizedCost"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_AvailableForSaleSecuritiesAmortizedCost" xml:lang="en-US">Total investment securities available for sale, Amortized Cost</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesAmortizedCost" xml:lang="en-US">Available-for-sale Securities, Amortized Cost Basis</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesAmortizedCost" xlink:to="label_us-gaap_AvailableForSaleSecuritiesAmortizedCost"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesFairValueAbstract" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesFairValueAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesFairValueAbstract" xml:lang="en-US">Available for sale</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesFairValueAbstract" xlink:to="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesFairValueAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xml:lang="en-US">Contractual Maturities, Less than one year, Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:to="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureNextTwelveMonth" xlink:label="locator_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureNextTwelveMonth"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureNextTwelveMonth" xml:lang="en-US">Contractual Maturities, Less than one year, Yield</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureNextTwelveMonth" xml:lang="en-US">Contractual yield on debt securities expected to mature next twelve month.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureNextTwelveMonth" xlink:to="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureNextTwelveMonth"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue" xml:lang="en-US">Contractual Maturities, One to five years, Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue" xlink:to="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterOneAndThroughFiveYear" xlink:label="locator_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterOneAndThroughFiveYear"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterOneAndThroughFiveYear" xml:lang="en-US">Contractual Maturities, One to five years, Yield</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterOneAndThroughFiveYear" xml:lang="en-US">Contractual yield on debt securities expected to mature after one and through five year.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterOneAndThroughFiveYear" xlink:to="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterOneAndThroughFiveYear"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue" xml:lang="en-US">Contractual Maturities, Five to ten years, Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue" xlink:to="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterFiveAndThroughTenYears" xlink:label="locator_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterFiveAndThroughTenYears"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterFiveAndThroughTenYears" xml:lang="en-US">Contractual Maturities, Five to ten years, Yield</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterFiveAndThroughTenYears" xml:lang="en-US">Contractual yield on debt securities expected to mature after five and through ten years.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterFiveAndThroughTenYears" xlink:to="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterFiveAndThroughTenYears"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue" xml:lang="en-US">Contractual Maturities, Over ten years, Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue" xlink:to="label_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterTenYears" xlink:label="locator_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterTenYears"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterTenYears" xml:lang="en-US">Contractual Maturities, Over ten years, Yield</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterTenYears" xml:lang="en-US">Contractual yield on debt securities expected to mature after ten years.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterTenYears" xlink:to="label_sfst_ContractualYieldOnDebtSecuritiesExpectedToMatureAfterTenYears"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ContractualMaturitiesYieldOnDebtSecurities" xlink:label="locator_sfst_ContractualMaturitiesYieldOnDebtSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ContractualMaturitiesYieldOnDebtSecurities" xml:lang="en-US">Contractual Maturities, Total, Yield</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ContractualMaturitiesYieldOnDebtSecurities" xml:lang="en-US">Contractual maturities yield on debt securities.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ContractualMaturitiesYieldOnDebtSecurities" xlink:to="label_sfst_ContractualMaturitiesYieldOnDebtSecurities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue" xml:lang="en-US">Available for sale Securities, Less than 12 months, Fair value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue" xlink:to="label_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss" xlink:label="locator_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss" xml:lang="en-US">Available for sale Securities, Less than 12 months, Unrealized losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss" xlink:to="label_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xlink:label="locator_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionTwelveMonthsOrLonger"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xml:lang="en-US">Available for sale Securities, 12 months or longer, Number of investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xml:lang="en-US">Number of investments in continuous unrealized loss position twelve months or longer.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionTwelveMonthsOrLonger" xlink:to="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPositionTwelveMonthsOrLonger"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue" xml:lang="en-US">Available for sale Securities, 12 months or longer, Fair value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue" xlink:to="label_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss" xlink:label="locator_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss" xml:lang="en-US">Available for sale Securities, 12 months or Longer, Unrealized losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss" xlink:to="label_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NumberOfInvestmentsInContinuousUnrealizedLossPosition" xlink:label="locator_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPosition"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPosition" xml:lang="en-US">Available for sale Securities, Total, Number of investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPosition" xml:lang="en-US">Number of investments in continuous unrealized loss position.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPosition" xlink:to="label_sfst_NumberOfInvestmentsInContinuousUnrealizedLossPosition"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue" xlink:label="locator_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue" xml:lang="en-US">Available for sale Securities, Total, Fair value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue" xlink:to="label_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss" xlink:label="locator_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss" xml:lang="en-US">Available for sale Securities, Total, Unrealized losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss" xlink:to="label_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherInvestmentsAbstract" xlink:label="locator_us-gaap_OtherInvestmentsAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_OtherInvestmentsAbstract" xml:lang="en-US">Other investments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherInvestmentsAbstract" xlink:to="label_us-gaap_OtherInvestmentsAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentInFederalHomeLoanBankStockFairValueDisclosure" xlink:label="locator_us-gaap_InvestmentInFederalHomeLoanBankStockFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InvestmentInFederalHomeLoanBankStockFairValueDisclosure" xml:lang="en-US">Federal Home Loan Bank stock</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InvestmentInFederalHomeLoanBankStockFairValueDisclosure" xlink:to="label_us-gaap_InvestmentInFederalHomeLoanBankStockFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CertificatesOfDepositAtCarryingValue" xlink:label="locator_us-gaap_CertificatesOfDepositAtCarryingValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_CertificatesOfDepositAtCarryingValue" xml:lang="en-US">Other investments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CertificatesOfDepositAtCarryingValue" xml:lang="en-US">Certificates of Deposit, at Carrying Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CertificatesOfDepositAtCarryingValue" xlink:to="label_us-gaap_CertificatesOfDepositAtCarryingValue"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_InvestmentInTrustPreferredSecurities" xlink:label="locator_sfst_InvestmentInTrustPreferredSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_InvestmentInTrustPreferredSecurities" xml:lang="en-US">Investment in Trust Preferred securities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_InvestmentInTrustPreferredSecurities" xml:lang="en-US">Investment in trust preferred securities.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_InvestmentInTrustPreferredSecurities" xlink:to="label_sfst_InvestmentInTrustPreferredSecurities"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_MortgageLoansHeldForSaleTextualAbstract" xlink:label="locator_sfst_MortgageLoansHeldForSaleTextualAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_MortgageLoansHeldForSaleTextualAbstract" xml:lang="en-US">Mortgage Loans Held for Sale (Textual)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_MortgageLoansHeldForSaleTextualAbstract" xlink:to="label_sfst_MortgageLoansHeldForSaleTextualAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MortgagesHeldForSaleFairValueDisclosure" xlink:label="locator_us-gaap_MortgagesHeldForSaleFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_MortgagesHeldForSaleFairValueDisclosure" xml:lang="en-US">Mortgage loans held for sale, fair value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_MortgagesHeldForSaleFairValueDisclosure" xlink:to="label_us-gaap_MortgagesHeldForSaleFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable" xlink:label="locator_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable" xml:lang="en-US">Financing Receivable, Allowance for Credit Loss [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable" xlink:to="label_us-gaap_ScheduleOfFinancingReceivableAllowanceForCreditLossesTable"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_PaycheckProtectionProgramMember" xlink:label="locator_sfst_PaycheckProtectionProgramMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_PaycheckProtectionProgramMember" xml:lang="en-US">Paycheck Protection Program [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_PaycheckProtectionProgramMember" xml:lang="en-US">Paycheck Protection Program [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_PaycheckProtectionProgramMember" xlink:to="label_sfst_PaycheckProtectionProgramMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ACAPSMELLCMember" xlink:label="locator_sfst_ACAPSMELLCMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ACAPSMELLCMember" xml:lang="en-US">ACAP SME LLC [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ACAPSMELLCMember" xlink:to="label_sfst_ACAPSMELLCMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoanAndAllowanceForLoanLossesTextualAbstract" xlink:label="locator_sfst_LoanAndAllowanceForLoanLossesTextualAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoanAndAllowanceForLoanLossesTextualAbstract" xml:lang="en-US">Loans and Allowance for Loan Losses (Textual)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoanAndAllowanceForLoanLossesTextualAbstract" xml:lang="en-US">Loan and allowance for loan losses textual.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoanAndAllowanceForLoanLossesTextualAbstract" xlink:to="label_sfst_LoanAndAllowanceForLoanLossesTextualAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_PercentageOfSbaToGuaranteeOfCertainLoans" xlink:label="locator_sfst_PercentageOfSbaToGuaranteeOfCertainLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_PercentageOfSbaToGuaranteeOfCertainLoans" xml:lang="en-US">Percentage of SBA to guarantee of certain loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_PercentageOfSbaToGuaranteeOfCertainLoans" xml:lang="en-US">Percentage of SBA to guarantee of certain loans.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_PercentageOfSbaToGuaranteeOfCertainLoans" xlink:to="label_sfst_PercentageOfSbaToGuaranteeOfCertainLoans"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NumberOfLoanProcessed" xlink:label="locator_sfst_NumberOfLoanProcessed"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NumberOfLoanProcessed" xml:lang="en-US">Number of loan processed</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NumberOfLoanProcessed" xml:lang="en-US">Number of loan processed.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NumberOfLoanProcessed" xlink:to="label_sfst_NumberOfLoanProcessed"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansAndLeasesReceivableLoansInProcess" xlink:label="locator_us-gaap_LoansAndLeasesReceivableLoansInProcess"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansAndLeasesReceivableLoansInProcess" xml:lang="en-US">Loans receivables</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansAndLeasesReceivableLoansInProcess" xlink:to="label_us-gaap_LoansAndLeasesReceivableLoansInProcess"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_PartOfLoansOfThirtyDaysOrMorePastDueAsPercentageOfAggregateLoanPortfolio" xlink:label="locator_sfst_PartOfLoansOfThirtyDaysOrMorePastDueAsPercentageOfAggregateLoanPortfolio"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_PartOfLoansOfThirtyDaysOrMorePastDueAsPercentageOfAggregateLoanPortfolio" xml:lang="en-US">Part of loans of 30 days or more past due as a percentage of total loan portfolio</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_PartOfLoansOfThirtyDaysOrMorePastDueAsPercentageOfAggregateLoanPortfolio" xml:lang="en-US">Part of loans of thirty days or more past due as a percentage of aggregate loan portfolio.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_PartOfLoansOfThirtyDaysOrMorePastDueAsPercentageOfAggregateLoanPortfolio" xlink:to="label_sfst_PartOfLoansOfThirtyDaysOrMorePastDueAsPercentageOfAggregateLoanPortfolio"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansAndLeasesReceivableDeferredIncome" xlink:label="locator_us-gaap_LoansAndLeasesReceivableDeferredIncome"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansAndLeasesReceivableDeferredIncome" xml:lang="en-US">Net of deferred loan fees and costs</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansAndLeasesReceivableDeferredIncome" xlink:to="label_us-gaap_LoansAndLeasesReceivableDeferredIncome"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NetLenderFees1" xlink:label="locator_sfst_NetLenderFees1"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NetLenderFees1" xml:lang="en-US">Net lender fees</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NetLenderFees1" xml:lang="en-US">Net lender fees</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NetLenderFees1" xlink:to="label_sfst_NetLenderFees1"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable" xlink:label="locator_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable" xml:lang="en-US">Schedule of Accounts, Notes, Loans and Financing Receivable [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable" xlink:to="label_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis" xlink:label="locator_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis" xml:lang="en-US">Class of Financing Receivable, Type [Axis]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis" xml:lang="en-US">Class of Financing Receivable [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis" xlink:to="label_us-gaap_FinancingReceivableRecordedInvestmentByClassOfFinancingReceivableAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConstructionLoansMember" xlink:label="locator_us-gaap_ConstructionLoansMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ConstructionLoansMember" xml:lang="en-US">Construction Loans [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ConstructionLoansMember" xlink:to="label_us-gaap_ConstructionLoansMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RealEstateLoanMember" xlink:label="locator_us-gaap_RealEstateLoanMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_RealEstateLoanMember" xml:lang="en-US">Real Estate Loan [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_RealEstateLoanMember" xlink:to="label_us-gaap_RealEstateLoanMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_HomeEquityLoanMember" xlink:label="locator_us-gaap_HomeEquityLoanMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_HomeEquityLoanMember" xml:lang="en-US">Home Equity Loan [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_HomeEquityLoanMember" xlink:to="label_us-gaap_HomeEquityLoanMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis" xlink:label="locator_us-gaap_LongtermDebtTypeAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LongtermDebtTypeAxis" xml:lang="en-US">Long-term Debt, Type [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LongtermDebtTypeAxis" xlink:to="label_us-gaap_LongtermDebtTypeAxis"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_OwnerOccupiedReMember" xlink:label="locator_sfst_OwnerOccupiedReMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_OwnerOccupiedReMember" xml:lang="en-US">Owner Occupied Re [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_OwnerOccupiedReMember" xml:lang="en-US">Owner occupied Real Estate.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_OwnerOccupiedReMember" xlink:to="label_sfst_OwnerOccupiedReMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonOwnerOccupiedReMember" xlink:label="locator_sfst_NonOwnerOccupiedReMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonOwnerOccupiedReMember" xml:lang="en-US">Non Owner Occupied Re [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonOwnerOccupiedReMember" xml:lang="en-US">Non owner occupied real estate.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonOwnerOccupiedReMember" xlink:to="label_sfst_NonOwnerOccupiedReMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_BusinessLoanMember" xlink:label="locator_sfst_BusinessLoanMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_BusinessLoanMember" xml:lang="en-US">Business Loan [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_BusinessLoanMember" xml:lang="en-US">Business loan.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_BusinessLoanMember" xlink:to="label_sfst_BusinessLoanMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_OtherConsumerMember" xlink:label="locator_sfst_OtherConsumerMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_OtherConsumerMember" xml:lang="en-US">Other Consumer [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_OtherConsumerMember" xml:lang="en-US">Other consumer.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_OtherConsumerMember" xlink:to="label_sfst_OtherConsumerMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsNotesAndLoansReceivableLineItems" xlink:label="locator_us-gaap_AccountsNotesAndLoansReceivableLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AccountsNotesAndLoansReceivableLineItems" xml:lang="en-US">Accounts, Notes, Loans and Financing Receivable [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AccountsNotesAndLoansReceivableLineItems" xlink:to="label_us-gaap_AccountsNotesAndLoansReceivableLineItems"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansAndLeasesReceivableNetReportedAmountAbstract" xlink:label="locator_us-gaap_LoansAndLeasesReceivableNetReportedAmountAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansAndLeasesReceivableNetReportedAmountAbstract" xml:lang="en-US">Composition of loan portfolio</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansAndLeasesReceivableNetReportedAmountAbstract" xlink:to="label_us-gaap_LoansAndLeasesReceivableNetReportedAmountAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoansAndLeasesReceivableNetOfDeferredIncomePercentage" xlink:label="locator_sfst_LoansAndLeasesReceivableNetOfDeferredIncomePercentage"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomePercentage" xml:lang="en-US">Total gross loans, net of deferred fees, (Percentage)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomePercentage" xml:lang="en-US">Loans and leases receivable net of deferred income percentage.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoansAndLeasesReceivableNetOfDeferredIncomePercentage" xlink:to="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomePercentage"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesOneYearOrLess" xlink:label="locator_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesOneYearOrLess"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesOneYearOrLess" xml:lang="en-US">Total gross loans, net of deferred fees, One year or less</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesOneYearOrLess" xml:lang="en-US">Loans and leases receivable net of deferred income maturities one year or less.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesOneYearOrLess" xlink:to="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesOneYearOrLess"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterOneButWithinFiveYears" xlink:label="locator_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterOneButWithinFiveYears"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterOneButWithinFiveYears" xml:lang="en-US">Total gross loans, net of deferred fees, After one but within five years</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterOneButWithinFiveYears" xml:lang="en-US">Loans and leases receivable net of deferred income maturities after one but within five years.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterOneButWithinFiveYears" xlink:to="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterOneButWithinFiveYears"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterFiveYears" xlink:label="locator_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterFiveYears"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterFiveYears" xml:lang="en-US">Total gross loans, net of deferred fees, After five years</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterFiveYears" xml:lang="en-US">Loans and leases receivable net of deferred income maturities after five years.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterFiveYears" xlink:to="label_sfst_LoansAndLeasesReceivableNetOfDeferredIncomeMaturitiesAfterFiveYears"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoansMaturingAfterOneYearWithFixedInterestRates" xlink:label="locator_sfst_LoansMaturingAfterOneYearWithFixedInterestRates"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoansMaturingAfterOneYearWithFixedInterestRates" xml:lang="en-US">Loans maturing after one year with: fixed interest rates</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoansMaturingAfterOneYearWithFixedInterestRates" xml:lang="en-US">Loans maturing after one year with fixed interest rates.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoansMaturingAfterOneYearWithFixedInterestRates" xlink:to="label_sfst_LoansMaturingAfterOneYearWithFixedInterestRates"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoansMaturingAfterOneYearWithFloatingInterestRates" xlink:label="locator_sfst_LoansMaturingAfterOneYearWithFloatingInterestRates"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoansMaturingAfterOneYearWithFloatingInterestRates" xml:lang="en-US">Loans maturing after one year with: floating interest rates</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoansMaturingAfterOneYearWithFloatingInterestRates" xml:lang="en-US">Loans maturing after one year with floating interest rates.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoansMaturingAfterOneYearWithFloatingInterestRates" xlink:to="label_sfst_LoansMaturingAfterOneYearWithFloatingInterestRates"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivablesPeriodPastDueAxis" xlink:label="locator_us-gaap_FinancingReceivablesPeriodPastDueAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivablesPeriodPastDueAxis" xml:lang="en-US">Financial Asset, Aging [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivablesPeriodPastDueAxis" xlink:to="label_us-gaap_FinancingReceivablesPeriodPastDueAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialAssetNotPastDueMember" xlink:label="locator_us-gaap_FinancialAssetNotPastDueMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancialAssetNotPastDueMember" xml:lang="en-US">Current [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancialAssetNotPastDueMember" xlink:to="label_us-gaap_FinancialAssetNotPastDueMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivables30To59DaysPastDueMember" xlink:label="locator_us-gaap_FinancingReceivables30To59DaysPastDueMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivables30To59DaysPastDueMember" xml:lang="en-US">30-59 days past due [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivables30To59DaysPastDueMember" xlink:to="label_us-gaap_FinancingReceivables30To59DaysPastDueMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivables60To89DaysPastDueMember" xlink:label="locator_us-gaap_FinancingReceivables60To89DaysPastDueMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivables60To89DaysPastDueMember" xml:lang="en-US">60-89 days past due [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivables60To89DaysPastDueMember" xlink:to="label_us-gaap_FinancingReceivables60To89DaysPastDueMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember" xlink:label="locator_us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember" xml:lang="en-US">Greater than 90 days [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember" xlink:to="label_us-gaap_FinancingReceivablesEqualToGreaterThan90DaysPastDueMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesReceivableNetAbstract" xlink:label="locator_us-gaap_NotesReceivableNetAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NotesReceivableNetAbstract" xml:lang="en-US">Outstanding commercial and consumer loans which include loans on nonaccrual status</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NotesReceivableNetAbstract" xlink:to="label_us-gaap_NotesReceivableNetAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NotesReceivableGross" xlink:label="locator_us-gaap_NotesReceivableGross"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NotesReceivableGross" xml:lang="en-US">Total commercial loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_NotesReceivableGross" xml:lang="en-US">Total consumer loans</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NotesReceivableGross" xlink:to="label_us-gaap_NotesReceivableGross"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable" xlink:label="locator_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable" xml:lang="en-US">Financing Receivable, Credit Quality Indicator [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable" xlink:to="label_us-gaap_ScheduleOfFinancingReceivableRecordedInvestmentCreditQualityIndicatorTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InternalCreditAssessmentAxis" xlink:label="locator_us-gaap_InternalCreditAssessmentAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InternalCreditAssessmentAxis" xml:lang="en-US">Internal Credit Assessment [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InternalCreditAssessmentAxis" xlink:to="label_us-gaap_InternalCreditAssessmentAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PassMember" xlink:label="locator_us-gaap_PassMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_PassMember" xml:lang="en-US">Pass [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_PassMember" xlink:to="label_us-gaap_PassMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SpecialMentionMember" xlink:label="locator_us-gaap_SpecialMentionMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SpecialMentionMember" xml:lang="en-US">Special Mention [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SpecialMentionMember" xlink:to="label_us-gaap_SpecialMentionMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubstandardMember" xlink:label="locator_us-gaap_SubstandardMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SubstandardMember" xml:lang="en-US">Substandard [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SubstandardMember" xlink:to="label_us-gaap_SubstandardMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DoubtfulMember" xlink:label="locator_us-gaap_DoubtfulMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DoubtfulMember" xml:lang="en-US">Doubtful [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DoubtfulMember" xlink:to="label_us-gaap_DoubtfulMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentLineItems" xlink:label="locator_us-gaap_FinancingReceivableRecordedInvestmentLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableRecordedInvestmentLineItems" xml:lang="en-US">Financing Receivable, Credit Quality Indicator [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableRecordedInvestmentLineItems" xlink:to="label_us-gaap_FinancingReceivableRecordedInvestmentLineItems"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_OutstandingLoansByRiskCategoryAbstract" xlink:label="locator_sfst_OutstandingLoansByRiskCategoryAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_OutstandingLoansByRiskCategoryAbstract" xml:lang="en-US">Outstanding commercial and consumer loans by risk category</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_OutstandingLoansByRiskCategoryAbstract" xlink:to="label_sfst_OutstandingLoansByRiskCategoryAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansAndLeasesReceivableBeforeFeesGross" xlink:label="locator_us-gaap_LoansAndLeasesReceivableBeforeFeesGross"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansAndLeasesReceivableBeforeFeesGross" xml:lang="en-US">Outstanding commercial loans</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansAndLeasesReceivableBeforeFeesGross" xlink:to="label_us-gaap_LoansAndLeasesReceivableBeforeFeesGross"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RealEstateMember" xlink:label="locator_us-gaap_RealEstateMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_RealEstateMember" xml:lang="en-US">Real Estate [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_RealEstateMember" xlink:to="label_us-gaap_RealEstateMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoanAndLeasesReceivableBeforeFeesGross" xlink:label="locator_sfst_LoanAndLeasesReceivableBeforeFeesGross"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoanAndLeasesReceivableBeforeFeesGross" xml:lang="en-US">Outstanding consumer loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoanAndLeasesReceivableBeforeFeesGross" xml:lang="en-US">Amount, before allowance and fees, of loans and leases receivable. Excludes loans and leases covered under loss sharing agreements.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoanAndLeasesReceivableBeforeFeesGross" xlink:to="label_sfst_LoanAndLeasesReceivableBeforeFeesGross"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems" xlink:label="locator_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems" xml:lang="en-US">Financing Receivable, Past Due [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems" xlink:to="label_us-gaap_FinancingReceivableRecordedInvestmentPastDueLineItems"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SummeryOfNonperformingAssetsAbstract" xlink:label="locator_sfst_SummeryOfNonperformingAssetsAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SummeryOfNonperformingAssetsAbstract" xml:lang="en-US">Summary of nonperforming assets</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SummeryOfNonperformingAssetsAbstract" xlink:to="label_sfst_SummeryOfNonperformingAssetsAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_Nonaccruing" xlink:label="locator_sfst_Nonaccruing"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_Nonaccruing" xml:lang="en-US">Nonaccruing</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_Nonaccruing" xml:lang="en-US">Nonaccruing TDRS.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_Nonaccruing" xlink:to="label_sfst_Nonaccruing"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonaccruingTroubledDebtRestructurings" xlink:label="locator_sfst_NonaccruingTroubledDebtRestructurings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonaccruingTroubledDebtRestructurings" xml:lang="en-US">Nonaccruing troubled debt restructurings</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonaccruingTroubledDebtRestructurings" xml:lang="en-US">Nonaccruing troubled debt restructurings.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonaccruingTroubledDebtRestructurings" xlink:to="label_sfst_NonaccruingTroubledDebtRestructurings"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonaccrualLoansIncludingNonaccruingTroubledDebtRestructurings" xlink:label="locator_sfst_NonaccrualLoansIncludingNonaccruingTroubledDebtRestructurings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonaccrualLoansIncludingNonaccruingTroubledDebtRestructurings" xml:lang="en-US">Total nonaccrual loans, including nonaccruing TDRs</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonaccrualLoansIncludingNonaccruingTroubledDebtRestructurings" xml:lang="en-US">Recorded investment in financing receivables that are on nonaccrual status as of the balance sheet date.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonaccrualLoansIncludingNonaccruingTroubledDebtRestructurings" xlink:to="label_sfst_NonaccrualLoansIncludingNonaccruingTroubledDebtRestructurings"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherRealEstate" xlink:label="locator_us-gaap_OtherRealEstate"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherRealEstate" xml:lang="en-US">Other real estate owned</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherRealEstate" xlink:to="label_us-gaap_OtherRealEstate"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonaccrualLoansAndOtherRealEstate" xlink:label="locator_sfst_NonaccrualLoansAndOtherRealEstate"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonaccrualLoansAndOtherRealEstate" xml:lang="en-US">Total nonperforming assets</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonaccrualLoansAndOtherRealEstate" xml:lang="en-US">Total nonperforming assets consist of nonaccrual loans and other Real Estate.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonaccrualLoansAndOtherRealEstate" xlink:to="label_sfst_NonaccrualLoansAndOtherRealEstate"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonperformingAssetsInRelativePercentageAbstract" xlink:label="locator_sfst_NonperformingAssetsInRelativePercentageAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonperformingAssetsInRelativePercentageAbstract" xml:lang="en-US">Nonperforming assets as a percentage of:</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonperformingAssetsInRelativePercentageAbstract" xml:lang="en-US">Nonperforming assets in relative percentage.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonperformingAssetsInRelativePercentageAbstract" xlink:to="label_sfst_NonperformingAssetsInRelativePercentageAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonperformingAssetsAsPercentageOfAssets" xlink:label="locator_sfst_NonperformingAssetsAsPercentageOfAssets"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonperformingAssetsAsPercentageOfAssets" xml:lang="en-US">Total assets</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonperformingAssetsAsPercentageOfAssets" xml:lang="en-US">Nonperforming assets as a percentage of Assets.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonperformingAssetsAsPercentageOfAssets" xlink:to="label_sfst_NonperformingAssetsAsPercentageOfAssets"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NonperformingAssetsAsPercentageOfGrossLoans" xlink:label="locator_sfst_NonperformingAssetsAsPercentageOfGrossLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NonperformingAssetsAsPercentageOfGrossLoans" xml:lang="en-US">Gross loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NonperformingAssetsAsPercentageOfGrossLoans" xml:lang="en-US">Nonperforming assets as a percentage of Gross loans.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NonperformingAssetsAsPercentageOfGrossLoans" xlink:to="label_sfst_NonperformingAssetsAsPercentageOfGrossLoans"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoansOverNinetyDaysPastDue" xlink:label="locator_sfst_LoansOverNinetyDaysPastDue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoansOverNinetyDaysPastDue" xml:lang="en-US">Total loans over 90 days past due</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoansOverNinetyDaysPastDue" xml:lang="en-US">Loans over ninety days past due.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoansOverNinetyDaysPastDue" xlink:to="label_sfst_LoansOverNinetyDaysPastDue"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestment90DaysPastDueAndStillAccruing" xlink:label="locator_us-gaap_FinancingReceivableRecordedInvestment90DaysPastDueAndStillAccruing"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableRecordedInvestment90DaysPastDueAndStillAccruing" xml:lang="en-US">Loans over 90 days past due and still accruing</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableRecordedInvestment90DaysPastDueAndStillAccruing" xlink:to="label_us-gaap_FinancingReceivableRecordedInvestment90DaysPastDueAndStillAccruing"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AccruingTroubledDebtRestructurings" xlink:label="locator_sfst_AccruingTroubledDebtRestructurings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AccruingTroubledDebtRestructurings" xml:lang="en-US">Accruing troubled debt restructurings</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AccruingTroubledDebtRestructurings" xml:lang="en-US">Accruing troubled debt restructurings.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AccruingTroubledDebtRestructurings" xlink:to="label_sfst_AccruingTroubledDebtRestructurings"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfImpairedFinancingReceivableTable" xlink:label="locator_us-gaap_ScheduleOfImpairedFinancingReceivableTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfImpairedFinancingReceivableTable" xml:lang="en-US">Schedule of Impaired Financing Receivable [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfImpairedFinancingReceivableTable" xlink:to="label_us-gaap_ScheduleOfImpairedFinancingReceivableTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableImpairedLineItems" xlink:label="locator_us-gaap_FinancingReceivableImpairedLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableImpairedLineItems" xml:lang="en-US">Financing Receivable, Impaired [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableImpairedLineItems" xlink:to="label_us-gaap_FinancingReceivableImpairedLineItems"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SummaryOfKeyInformationForImpairedLoansAbstract" xlink:label="locator_sfst_SummaryOfKeyInformationForImpairedLoansAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SummaryOfKeyInformationForImpairedLoansAbstract" xml:lang="en-US">Summary of key information for impaired loans</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SummaryOfKeyInformationForImpairedLoansAbstract" xlink:to="label_sfst_SummaryOfKeyInformationForImpairedLoansAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivableUnpaidPrincipalBalance" xlink:label="locator_us-gaap_ImpairedFinancingReceivableUnpaidPrincipalBalance"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivableUnpaidPrincipalBalance" xml:lang="en-US">Unpaid Principal Balance</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivableUnpaidPrincipalBalance" xlink:to="label_us-gaap_ImpairedFinancingReceivableUnpaidPrincipalBalance"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivableRecordedInvestment" xlink:label="locator_us-gaap_ImpairedFinancingReceivableRecordedInvestment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivableRecordedInvestment" xml:lang="en-US">Impaired loans</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivableRecordedInvestment" xlink:to="label_us-gaap_ImpairedFinancingReceivableRecordedInvestment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivableWithNoRelatedAllowanceRecordedInvestment" xlink:label="locator_us-gaap_ImpairedFinancingReceivableWithNoRelatedAllowanceRecordedInvestment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivableWithNoRelatedAllowanceRecordedInvestment" xml:lang="en-US">Impaired loans with no related allowance for loan losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivableWithNoRelatedAllowanceRecordedInvestment" xlink:to="label_us-gaap_ImpairedFinancingReceivableWithNoRelatedAllowanceRecordedInvestment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivableWithRelatedAllowanceRecordedInvestment" xlink:label="locator_us-gaap_ImpairedFinancingReceivableWithRelatedAllowanceRecordedInvestment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivableWithRelatedAllowanceRecordedInvestment" xml:lang="en-US">Impaired loans with related allowance for loan losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivableWithRelatedAllowanceRecordedInvestment" xlink:to="label_us-gaap_ImpairedFinancingReceivableWithRelatedAllowanceRecordedInvestment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivableRelatedAllowance" xlink:label="locator_us-gaap_ImpairedFinancingReceivableRelatedAllowance"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivableRelatedAllowance" xml:lang="en-US">Related allowance for loan losses</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivableRelatedAllowance" xlink:to="label_us-gaap_ImpairedFinancingReceivableRelatedAllowance"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivableAverageRecordedInvestmentAbstract" xlink:label="locator_us-gaap_ImpairedFinancingReceivableAverageRecordedInvestmentAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivableAverageRecordedInvestmentAbstract" xml:lang="en-US">Average recorded investment and interest income recognized on impaired loans</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivableAverageRecordedInvestmentAbstract" xlink:to="label_us-gaap_ImpairedFinancingReceivableAverageRecordedInvestmentAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivableAverageRecordedInvestment" xlink:label="locator_us-gaap_ImpairedFinancingReceivableAverageRecordedInvestment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivableAverageRecordedInvestment" xml:lang="en-US">Average recorded investment</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivableAverageRecordedInvestment" xlink:to="label_us-gaap_ImpairedFinancingReceivableAverageRecordedInvestment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ImpairedFinancingReceivableInterestIncomeAccrualMethod" xlink:label="locator_us-gaap_ImpairedFinancingReceivableInterestIncomeAccrualMethod"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ImpairedFinancingReceivableInterestIncomeAccrualMethod" xml:lang="en-US">Recognized interest income</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ImpairedFinancingReceivableInterestIncomeAccrualMethod" xlink:to="label_us-gaap_ImpairedFinancingReceivableInterestIncomeAccrualMethod"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward" xlink:label="locator_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward" xml:lang="en-US">Financing Receivable, Allowance For Credit Losses [Roll Forward]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward" xlink:to="label_us-gaap_FinancingReceivableAllowanceForCreditLossesRollForward"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLosses" xlink:label="locator_us-gaap_FinancingReceivableAllowanceForCreditLosses"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodStartLabel" xlink:label="label_us-gaap_FinancingReceivableAllowanceForCreditLosses" xml:lang="en-US">Balance, beginning of period</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/periodEndLabel" xlink:label="label_us-gaap_FinancingReceivableAllowanceForCreditLosses" xml:lang="en-US">Balance, end of period</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableAllowanceForCreditLosses" xml:lang="en-US">Allowance for loan losses, Total</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableAllowanceForCreditLosses" xlink:to="label_us-gaap_FinancingReceivableAllowanceForCreditLosses"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllowanceForLoanAndLeaseLossesWriteOffs" xlink:label="locator_us-gaap_AllowanceForLoanAndLeaseLossesWriteOffs"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_us-gaap_AllowanceForLoanAndLeaseLossesWriteOffs" xml:lang="en-US">Loan charge-offs</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AllowanceForLoanAndLeaseLossesWriteOffs" xml:lang="en-US">Allowance for Loan and Lease Losses, Write-offs</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AllowanceForLoanAndLeaseLossesWriteOffs" xlink:to="label_us-gaap_AllowanceForLoanAndLeaseLossesWriteOffs"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ValuationAllowancesAndReservesRecoveries" xlink:label="locator_us-gaap_ValuationAllowancesAndReservesRecoveries"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ValuationAllowancesAndReservesRecoveries" xml:lang="en-US">Loan recoveries</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ValuationAllowancesAndReservesRecoveries" xlink:to="label_us-gaap_ValuationAllowancesAndReservesRecoveries"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AllowanceForLoanAndLeaseLossesWriteOffsNetOfRecoveries" xlink:label="locator_sfst_AllowanceForLoanAndLeaseLossesWriteOffsNetOfRecoveries"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_sfst_AllowanceForLoanAndLeaseLossesWriteOffsNetOfRecoveries" xml:lang="en-US">Net loan charge-offs</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AllowanceForLoanAndLeaseLossesWriteOffsNetOfRecoveries" xml:lang="en-US">Allowance for loan and lease losses write offs net of recoveries.</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AllowanceForLoanAndLeaseLossesWriteOffsNetOfRecoveries" xml:lang="en-US">Allowance For Loan and Lease Losses Write Offs Net Of Recoveries</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AllowanceForLoanAndLeaseLossesWriteOffsNetOfRecoveries" xlink:to="label_sfst_AllowanceForLoanAndLeaseLossesWriteOffsNetOfRecoveries"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NetLoanChargeOffsAnnualizedAsPercentageOfAverageLoans" xlink:label="locator_sfst_NetLoanChargeOffsAnnualizedAsPercentageOfAverageLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NetLoanChargeOffsAnnualizedAsPercentageOfAverageLoans" xml:lang="en-US">Net charge-offs to average loans (annualized)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NetLoanChargeOffsAnnualizedAsPercentageOfAverageLoans" xml:lang="en-US">Net loan charge offs annualized as a percentage of average total loans.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NetLoanChargeOffsAnnualizedAsPercentageOfAverageLoans" xlink:to="label_sfst_NetLoanChargeOffsAnnualizedAsPercentageOfAverageLoans"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AllowanceForLoanLossesAsPercentageOfGrossLoans" xlink:label="locator_sfst_AllowanceForLoanLossesAsPercentageOfGrossLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AllowanceForLoanLossesAsPercentageOfGrossLoans" xml:lang="en-US">Allowance for loan losses to gross loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AllowanceForLoanLossesAsPercentageOfGrossLoans" xml:lang="en-US">Allowance for loan losses as a percentage of gross loans.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AllowanceForLoanLossesAsPercentageOfGrossLoans" xlink:to="label_sfst_AllowanceForLoanLossesAsPercentageOfGrossLoans"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AllowanceForLoanLossesAsPercentageOfNonperformingLoans" xlink:label="locator_sfst_AllowanceForLoanLossesAsPercentageOfNonperformingLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AllowanceForLoanLossesAsPercentageOfNonperformingLoans" xml:lang="en-US">Allowance for loan losses to nonperforming loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AllowanceForLoanLossesAsPercentageOfNonperformingLoans" xml:lang="en-US">Allowance for credit losses as a percentage of nonperforming loans.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AllowanceForLoanLossesAsPercentageOfNonperformingLoans" xlink:to="label_sfst_AllowanceForLoanLossesAsPercentageOfNonperformingLoans"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract" xlink:label="locator_us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract" xml:lang="en-US">Allowance for Loan Losses and Recorded Investment in Loans by Impairment</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract" xlink:to="label_us-gaap_FinancingReceivableAllowanceForCreditLossAdditionalInformationAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesIndividuallyEvaluatedForImpairment1" xlink:label="locator_us-gaap_FinancingReceivableAllowanceForCreditLossesIndividuallyEvaluatedForImpairment1"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableAllowanceForCreditLossesIndividuallyEvaluatedForImpairment1" xml:lang="en-US">Allowance for loan losses, Individually evaluated</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableAllowanceForCreditLossesIndividuallyEvaluatedForImpairment1" xlink:to="label_us-gaap_FinancingReceivableAllowanceForCreditLossesIndividuallyEvaluatedForImpairment1"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableIndividuallyEvaluatedForImpairment" xlink:label="locator_us-gaap_FinancingReceivableIndividuallyEvaluatedForImpairment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableIndividuallyEvaluatedForImpairment" xml:lang="en-US">Recorded investment in loans, Individually evaluated</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableIndividuallyEvaluatedForImpairment" xlink:to="label_us-gaap_FinancingReceivableIndividuallyEvaluatedForImpairment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesCollectivelyEvaluatedForImpairment" xlink:label="locator_us-gaap_FinancingReceivableAllowanceForCreditLossesCollectivelyEvaluatedForImpairment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableAllowanceForCreditLossesCollectivelyEvaluatedForImpairment" xml:lang="en-US">Allowance for loan losses, Collectively evaluated</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableAllowanceForCreditLossesCollectivelyEvaluatedForImpairment" xlink:to="label_us-gaap_FinancingReceivableAllowanceForCreditLossesCollectivelyEvaluatedForImpairment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment" xlink:label="locator_us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment" xml:lang="en-US">Recorded investment in loans, Collectively evaluated</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment" xlink:to="label_us-gaap_FinancingReceivableCollectivelyEvaluatedForImpairment"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_TroubledDebtRestructuringsTextualAbstract" xlink:label="locator_sfst_TroubledDebtRestructuringsTextualAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_TroubledDebtRestructuringsTextualAbstract" xml:lang="en-US">Troubled Debt Restructurings (Textual)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_TroubledDebtRestructuringsTextualAbstract" xml:lang="en-US">It covers narrative parts of troubled debt restructurings note.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_TroubledDebtRestructuringsTextualAbstract" xlink:to="label_sfst_TroubledDebtRestructuringsTextualAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AggregateNumberOfLoansClassifiedUnderTroubledDebtRestructurings" xlink:label="locator_sfst_AggregateNumberOfLoansClassifiedUnderTroubledDebtRestructurings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AggregateNumberOfLoansClassifiedUnderTroubledDebtRestructurings" xml:lang="en-US">Total number of loans classified under troubled debt restructurings (TDRs)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AggregateNumberOfLoansClassifiedUnderTroubledDebtRestructurings" xml:lang="en-US">Aggregate number of loans classified under troubled debt restructurings.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AggregateNumberOfLoansClassifiedUnderTroubledDebtRestructurings" xlink:to="label_sfst_AggregateNumberOfLoansClassifiedUnderTroubledDebtRestructurings"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AggregateSumOfLoansClassifiedAsTroubledDebtRestructurings" xlink:label="locator_sfst_AggregateSumOfLoansClassifiedAsTroubledDebtRestructurings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AggregateSumOfLoansClassifiedAsTroubledDebtRestructurings" xml:lang="en-US">Total sum of loans classified as troubled debt restructurings (TDRs)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AggregateSumOfLoansClassifiedAsTroubledDebtRestructurings" xml:lang="en-US">Aggregate sum of loans classified as troubled debt restructurings.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AggregateSumOfLoansClassifiedAsTroubledDebtRestructurings" xlink:to="label_sfst_AggregateSumOfLoansClassifiedAsTroubledDebtRestructurings"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AggregateNumberOfLoansAddedUnderTroubledDebtRestructurings" xlink:label="locator_sfst_AggregateNumberOfLoansAddedUnderTroubledDebtRestructurings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AggregateNumberOfLoansAddedUnderTroubledDebtRestructurings" xml:lang="en-US">Total number of loans added under troubled debt restructurings (TDRs)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AggregateNumberOfLoansAddedUnderTroubledDebtRestructurings" xml:lang="en-US">Aggregate number of loans added under troubled debt restructurings.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AggregateNumberOfLoansAddedUnderTroubledDebtRestructurings" xlink:to="label_sfst_AggregateNumberOfLoansAddedUnderTroubledDebtRestructurings"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AggregateSumOfLoansAddedAsTroubledDebtRestructurings" xlink:label="locator_sfst_AggregateSumOfLoansAddedAsTroubledDebtRestructurings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AggregateSumOfLoansAddedAsTroubledDebtRestructurings" xml:lang="en-US">Total sum of loans added as troubled debt restructurings (TDRs)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AggregateSumOfLoansAddedAsTroubledDebtRestructurings" xml:lang="en-US">Aggregate sum of loans added as troubled debt restructurings.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AggregateSumOfLoansAddedAsTroubledDebtRestructurings" xlink:to="label_sfst_AggregateSumOfLoansAddedAsTroubledDebtRestructurings"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AggregateNumberOfLoansRemovedUnderTroubledDebtRestructurings" xlink:label="locator_sfst_AggregateNumberOfLoansRemovedUnderTroubledDebtRestructurings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AggregateNumberOfLoansRemovedUnderTroubledDebtRestructurings" xml:lang="en-US">Total number of loans removed under TDR</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AggregateNumberOfLoansRemovedUnderTroubledDebtRestructurings" xml:lang="en-US">Aggregate number of loans removed under troubled debt restructurings.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AggregateNumberOfLoansRemovedUnderTroubledDebtRestructurings" xlink:to="label_sfst_AggregateNumberOfLoansRemovedUnderTroubledDebtRestructurings"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_RestoredNonaccrualLoans" xlink:label="locator_sfst_RestoredNonaccrualLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_RestoredNonaccrualLoans" xml:lang="en-US">Total number of nonaccrual loans restored</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_RestoredNonaccrualLoans" xml:lang="en-US">Restored nonaccrual loans.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_RestoredNonaccrualLoans" xlink:to="label_sfst_RestoredNonaccrualLoans"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NumberOfMonthPaymentDefaulted" xlink:label="locator_sfst_NumberOfMonthPaymentDefaulted"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NumberOfMonthPaymentDefaulted" xml:lang="en-US">Number of months previous loan payment defaulted</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NumberOfMonthPaymentDefaulted" xml:lang="en-US">Number of month payment defaulted.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NumberOfMonthPaymentDefaulted" xlink:to="label_sfst_NumberOfMonthPaymentDefaulted"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShortTermBorrowings" xlink:label="locator_us-gaap_ShortTermBorrowings"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ShortTermBorrowings" xml:lang="en-US">Short-term loan</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ShortTermBorrowings" xlink:to="label_us-gaap_ShortTermBorrowings"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableTroubledDebtRestructuringIncreaseDecreaseFromModification" xlink:label="locator_us-gaap_FinancingReceivableTroubledDebtRestructuringIncreaseDecreaseFromModification"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableTroubledDebtRestructuringIncreaseDecreaseFromModification" xml:lang="en-US">Pre-modification and post-modification balance of loan</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableTroubledDebtRestructuringIncreaseDecreaseFromModification" xlink:to="label_us-gaap_FinancingReceivableTroubledDebtRestructuringIncreaseDecreaseFromModification"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable" xlink:label="locator_us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable" xml:lang="en-US">Financing Receivable, Troubled Debt Restructuring [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable" xlink:to="label_us-gaap_ScheduleOfFinancingReceivableTroubledDebtRestructuringsTable"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_BusinessMember" xlink:label="locator_sfst_BusinessMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_BusinessMember" xml:lang="en-US">Business [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_BusinessMember" xml:lang="en-US">Business [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_BusinessMember" xlink:to="label_sfst_BusinessMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableModificationsLineItems" xlink:label="locator_us-gaap_FinancingReceivableModificationsLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableModificationsLineItems" xml:lang="en-US">Financing Receivable, Troubled Debt Restructuring [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableModificationsLineItems" xlink:to="label_us-gaap_FinancingReceivableModificationsLineItems"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SummaryOfConcessionAtTimeOfModificationAndRecordedInvestmentAbstract" xlink:label="locator_sfst_SummaryOfConcessionAtTimeOfModificationAndRecordedInvestmentAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SummaryOfConcessionAtTimeOfModificationAndRecordedInvestmentAbstract" xml:lang="en-US">Summary of concession at the time of modification and the recorded investment in TDRs before and after their modification</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SummaryOfConcessionAtTimeOfModificationAndRecordedInvestmentAbstract" xlink:to="label_sfst_SummaryOfConcessionAtTimeOfModificationAndRecordedInvestmentAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_RenewalsDeemedConcession" xlink:label="locator_sfst_RenewalsDeemedConcession"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_RenewalsDeemedConcession" xml:lang="en-US">Renewals deemed a concession</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_RenewalsDeemedConcession" xml:lang="en-US">Renewals deemed concession.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_RenewalsDeemedConcession" xlink:to="label_sfst_RenewalsDeemedConcession"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ReducedOrDeferredPayments" xlink:label="locator_sfst_ReducedOrDeferredPayments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ReducedOrDeferredPayments" xml:lang="en-US">Reduced or deferred payments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ReducedOrDeferredPayments" xml:lang="en-US">Reduced or deferred payments.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ReducedOrDeferredPayments" xlink:to="label_sfst_ReducedOrDeferredPayments"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ConvertedToInterestOnly" xlink:label="locator_sfst_ConvertedToInterestOnly"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ConvertedToInterestOnly" xml:lang="en-US">Converted to interest only</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ConvertedToInterestOnly" xml:lang="en-US">Converted to interest only.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ConvertedToInterestOnly" xlink:to="label_sfst_ConvertedToInterestOnly"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_MaturityDateExtensions" xlink:label="locator_sfst_MaturityDateExtensions"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_MaturityDateExtensions" xml:lang="en-US">Maturity date extensions</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_MaturityDateExtensions" xml:lang="en-US">Maturity date extensions.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_MaturityDateExtensions" xlink:to="label_sfst_MaturityDateExtensions"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_TotalNumberOfLoans" xlink:label="locator_sfst_TotalNumberOfLoans"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_TotalNumberOfLoans" xml:lang="en-US">Total number of loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_TotalNumberOfLoans" xml:lang="en-US">Total number of loans.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_TotalNumberOfLoans" xlink:to="label_sfst_TotalNumberOfLoans"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableModificationsPreModificationRecordedInvestment2" xlink:label="locator_us-gaap_FinancingReceivableModificationsPreModificationRecordedInvestment2"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableModificationsPreModificationRecordedInvestment2" xml:lang="en-US">Pre-modification outstanding recorded investment</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableModificationsPreModificationRecordedInvestment2" xlink:to="label_us-gaap_FinancingReceivableModificationsPreModificationRecordedInvestment2"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2" xlink:label="locator_us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2" xml:lang="en-US">Post-modification outstanding recorded investment</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2" xlink:to="label_us-gaap_FinancingReceivableModificationsPostModificationRecordedInvestment2"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable" xlink:label="locator_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable" xml:lang="en-US">Schedule of Fair Value, Off-balance Sheet Risks [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable" xlink:to="label_us-gaap_ScheduleOfFairValueOffBalanceSheetRisksTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestRateLockCommitmentsMember" xlink:label="locator_us-gaap_InterestRateLockCommitmentsMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_InterestRateLockCommitmentsMember" xml:lang="en-US">Interest Rate Lock Commitments [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_InterestRateLockCommitmentsMember" xlink:to="label_us-gaap_InterestRateLockCommitmentsMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SecuritiesSoldNotYetPurchasedMember" xlink:label="locator_us-gaap_SecuritiesSoldNotYetPurchasedMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SecuritiesSoldNotYetPurchasedMember" xml:lang="en-US">Securities Sold, Not yet Purchased [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SecuritiesSoldNotYetPurchasedMember" xlink:to="label_us-gaap_SecuritiesSoldNotYetPurchasedMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeMember" xlink:label="locator_us-gaap_DerivativeMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DerivativeMember" xml:lang="en-US">Derivative [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DerivativeMember" xlink:to="label_us-gaap_DerivativeMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosuresLineItems" xlink:label="locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosuresLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosuresLineItems" xml:lang="en-US">Derivative Instruments and Hedging Activities Disclosures [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosuresLineItems" xlink:to="label_us-gaap_DerivativeInstrumentsAndHedgingActivitiesDisclosuresLineItems"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_DerivativesNotionalAmount" xlink:label="locator_sfst_DerivativesNotionalAmount"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_DerivativesNotionalAmount" xml:lang="en-US">Notional</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_DerivativesNotionalAmount" xml:lang="en-US">Aggregate notional amount specified by the derivative(s). Expressed as an absolute value.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_DerivativesNotionalAmount" xlink:to="label_sfst_DerivativesNotionalAmount"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_BalanceSheetLocationDescription" xlink:label="locator_sfst_BalanceSheetLocationDescription"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_BalanceSheetLocationDescription" xml:lang="en-US">Balance Sheet Location, description</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_BalanceSheetLocationDescription" xml:lang="en-US">Description of balance sheet location.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_BalanceSheetLocationDescription" xlink:to="label_sfst_BalanceSheetLocationDescription"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet" xlink:label="locator_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet" xml:lang="en-US">Fair Value, Asset/(Liability)</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet" xml:lang="en-US">Mortgage loan interest rate lock commitments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet" xlink:to="label_us-gaap_DerivativeAssetsLiabilitiesAtFairValueNet"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:label="locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xml:lang="en-US">Fair Value, Recurring and Nonrecurring [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable" xlink:to="label_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis" xlink:label="locator_us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueByMeasurementFrequencyAxis" xml:lang="en-US">Measurement Frequency [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueByMeasurementFrequencyAxis" xlink:to="label_us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember" xlink:label="locator_us-gaap_FairValueMeasurementsRecurringMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueMeasurementsRecurringMember" xml:lang="en-US">Fair Value, Measurements, Recurring [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueMeasurementsRecurringMember" xlink:to="label_us-gaap_FairValueMeasurementsRecurringMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:label="locator_us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueByFairValueHierarchyLevelAxis" xml:lang="en-US">Fair Value, Hierarchy [Axis]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_FairValueByFairValueHierarchyLevelAxis" xml:lang="en-US">Fair Value Hierarchy and NAV [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueByFairValueHierarchyLevelAxis" xlink:to="label_us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel1Member" xlink:label="locator_us-gaap_FairValueInputsLevel1Member"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueInputsLevel1Member" xml:lang="en-US">Fair Value, Inputs, Level 1 [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueInputsLevel1Member" xlink:to="label_us-gaap_FairValueInputsLevel1Member"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel2Member" xlink:label="locator_us-gaap_FairValueInputsLevel2Member"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueInputsLevel2Member" xml:lang="en-US">Fair Value, Inputs, Level 2 [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueInputsLevel2Member" xlink:to="label_us-gaap_FairValueInputsLevel2Member"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel3Member" xlink:label="locator_us-gaap_FairValueInputsLevel3Member"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueInputsLevel3Member" xml:lang="en-US">Fair Value, Inputs, Level 3 [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueInputsLevel3Member" xlink:to="label_us-gaap_FairValueInputsLevel3Member"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:label="locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xml:lang="en-US">Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems" xlink:to="label_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisLineItems"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_FairValueAssetsAndLiabilitiesMeasuredAbstract" xlink:label="locator_sfst_FairValueAssetsAndLiabilitiesMeasuredAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_FairValueAssetsAndLiabilitiesMeasuredAbstract" xml:lang="en-US">Schedule of assets and liabilities measured at fair value on recurring basis</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_FairValueAssetsAndLiabilitiesMeasuredAbstract" xlink:to="label_sfst_FairValueAssetsAndLiabilitiesMeasuredAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosureAbstract" xlink:label="locator_us-gaap_AssetsFairValueDisclosureAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AssetsFairValueDisclosureAbstract" xml:lang="en-US">Assets</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AssetsFairValueDisclosureAbstract" xlink:to="label_us-gaap_AssetsFairValueDisclosureAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SecuritiesAvailableForSaleFairValueAbstract" xlink:label="locator_sfst_SecuritiesAvailableForSaleFairValueAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueAbstract" xml:lang="en-US">Securities available for sale</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SecuritiesAvailableForSaleFairValueAbstract" xlink:to="label_sfst_SecuritiesAvailableForSaleFairValueAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SecuritiesAvailableForSaleFairValueUsAgencyUSTreasuries" xlink:label="locator_sfst_SecuritiesAvailableForSaleFairValueUsAgencyUSTreasuries"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueUsAgencyUSTreasuries" xml:lang="en-US">US treasuries</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueUsAgencyUSTreasuries" xml:lang="en-US">US treasuries.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SecuritiesAvailableForSaleFairValueUsAgencyUSTreasuries" xlink:to="label_sfst_SecuritiesAvailableForSaleFairValueUsAgencyUSTreasuries"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SecuritiesAvailableForSaleFairValueUsAgencySecurities" xlink:label="locator_sfst_SecuritiesAvailableForSaleFairValueUsAgencySecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueUsAgencySecurities" xml:lang="en-US">US government agencies</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueUsAgencySecurities" xml:lang="en-US">Securities Available for Sale, Fair value, US agency securities.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SecuritiesAvailableForSaleFairValueUsAgencySecurities" xlink:to="label_sfst_SecuritiesAvailableForSaleFairValueUsAgencySecurities"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SecuritiesAvailableForSaleFairValueSbaSecurities" xlink:label="locator_sfst_SecuritiesAvailableForSaleFairValueSbaSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueSbaSecurities" xml:lang="en-US">SBA securities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueSbaSecurities" xml:lang="en-US">Securities Available for Sale, Fair value, SBA Securities.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SecuritiesAvailableForSaleFairValueSbaSecurities" xlink:to="label_sfst_SecuritiesAvailableForSaleFairValueSbaSecurities"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_SecuritiesAvailableForSaleFairValueStateAndPoliticalSubdivisions" xlink:label="locator_sfst_SecuritiesAvailableForSaleFairValueStateAndPoliticalSubdivisions"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueStateAndPoliticalSubdivisions" xml:lang="en-US">State and political subdivisions</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_SecuritiesAvailableForSaleFairValueStateAndPoliticalSubdivisions" xml:lang="en-US">Securities Available for Sale, Fair value, State and political subdivisions.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_SecuritiesAvailableForSaleFairValueStateAndPoliticalSubdivisions" xlink:to="label_sfst_SecuritiesAvailableForSaleFairValueStateAndPoliticalSubdivisions"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AssetBackedSecurities" xlink:label="locator_sfst_AssetBackedSecurities"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AssetBackedSecurities" xml:lang="en-US">Asset-backed securities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AssetBackedSecurities" xml:lang="en-US">Asset-backed securities.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AssetBackedSecurities" xlink:to="label_sfst_AssetBackedSecurities"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MortgageBackedSecuritiesAvailableForSaleFairValueDisclosure" xlink:label="locator_us-gaap_MortgageBackedSecuritiesAvailableForSaleFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_MortgageBackedSecuritiesAvailableForSaleFairValueDisclosure" xml:lang="en-US">Mortgage-backed securities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_MortgageBackedSecuritiesAvailableForSaleFairValueDisclosure" xlink:to="label_us-gaap_MortgageBackedSecuritiesAvailableForSaleFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansHeldForSaleFairValueDisclosure" xlink:label="locator_us-gaap_LoansHeldForSaleFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_LoansHeldForSaleFairValueDisclosure" xml:lang="en-US">Mortgage loans held for sale</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansHeldForSaleFairValueDisclosure" xml:lang="en-US">Loans Held-for-sale, Fair Value Disclosure</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansHeldForSaleFairValueDisclosure" xlink:to="label_us-gaap_LoansHeldForSaleFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_MortgageBackedSecuritiesForwardSalesCommitments" xlink:label="locator_sfst_MortgageBackedSecuritiesForwardSalesCommitments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_MortgageBackedSecuritiesForwardSalesCommitments" xml:lang="en-US">MBS forward sales commitments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_MortgageBackedSecuritiesForwardSalesCommitments" xml:lang="en-US">MBS forward sales commitments.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_MortgageBackedSecuritiesForwardSalesCommitments" xlink:to="label_sfst_MortgageBackedSecuritiesForwardSalesCommitments"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="locator_us-gaap_AssetsFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AssetsFairValueDisclosure" xml:lang="en-US">Total assets measured at fair value on a recurring basis</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AssetsFairValueDisclosure" xlink:to="label_us-gaap_AssetsFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:label="locator_us-gaap_LiabilitiesFairValueDisclosureAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LiabilitiesFairValueDisclosureAbstract" xml:lang="en-US">Liabilities</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LiabilitiesFairValueDisclosureAbstract" xlink:to="label_us-gaap_LiabilitiesFairValueDisclosureAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentsSoldNotYetPurchasedAtFairValue" xlink:label="locator_us-gaap_FinancialInstrumentsSoldNotYetPurchasedAtFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_us-gaap_FinancialInstrumentsSoldNotYetPurchasedAtFairValue" xml:lang="en-US">MBS forward sales commitments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancialInstrumentsSoldNotYetPurchasedAtFairValue" xml:lang="en-US">Financial Instruments Sold, Not yet Purchased, at Fair Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancialInstrumentsSoldNotYetPurchasedAtFairValue" xlink:to="label_us-gaap_FinancialInstrumentsSoldNotYetPurchasedAtFairValue"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="locator_us-gaap_LiabilitiesFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LiabilitiesFairValueDisclosure" xml:lang="en-US">Total liabilities measured at fair value on a recurring basis</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LiabilitiesFairValueDisclosure" xlink:to="label_us-gaap_LiabilitiesFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsNonrecurringMember" xlink:label="locator_us-gaap_FairValueMeasurementsNonrecurringMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueMeasurementsNonrecurringMember" xml:lang="en-US">Fair Value, Measurements, Nonrecurring [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueMeasurementsNonrecurringMember" xlink:to="label_us-gaap_FairValueMeasurementsNonrecurringMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_FairValueAssetsAndLiabilitiesMeasuredOnNonRecurringBasisAbstract" xlink:label="locator_sfst_FairValueAssetsAndLiabilitiesMeasuredOnNonRecurringBasisAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_FairValueAssetsAndLiabilitiesMeasuredOnNonRecurringBasisAbstract" xml:lang="en-US">Schedule of assets and liabilities measured on a nonrecurring basis</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_FairValueAssetsAndLiabilitiesMeasuredOnNonRecurringBasisAbstract" xlink:to="label_sfst_FairValueAssetsAndLiabilitiesMeasuredOnNonRecurringBasisAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ImpairedLoansFairValue" xlink:label="locator_sfst_ImpairedLoansFairValue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_sfst_ImpairedLoansFairValue" xml:lang="en-US">Impaired loans</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ImpairedLoansFairValue" xml:lang="en-US">Impaired loans, Fair value.</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ImpairedLoansFairValue" xml:lang="en-US">Leases Textual [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ImpairedLoansFairValue" xlink:to="label_sfst_ImpairedLoansFairValue"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_OtherRealEstateOwned" xlink:label="locator_sfst_OtherRealEstateOwned"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/verboseLabel" xlink:label="label_sfst_OtherRealEstateOwned" xml:lang="en-US">Other real estate owned</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_OtherRealEstateOwned" xml:lang="en-US">Other real estate owned.</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_OtherRealEstateOwned" xml:lang="en-US">Other Real Estate Owned</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_OtherRealEstateOwned" xlink:to="label_sfst_OtherRealEstateOwned"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_AssetsFairValueDisclosuresNonRecurring" xlink:label="locator_sfst_AssetsFairValueDisclosuresNonRecurring"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_AssetsFairValueDisclosuresNonRecurring" xml:lang="en-US">Total assets measured at fair value on a nonrecurring basis</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_AssetsFairValueDisclosuresNonRecurring" xml:lang="en-US">This element represents the aggregate of the assets reported on the balance sheet at period end measured at fair value on a nonrecurring basis by the entity. This element is intended to be used in connection with the fair value disclosures required in the footnote disclosures to the financial statements.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_AssetsFairValueDisclosuresNonRecurring" xlink:to="label_sfst_AssetsFairValueDisclosuresNonRecurring"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByBalanceSheetGroupingTable" xlink:label="locator_us-gaap_FairValueByBalanceSheetGroupingTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueByBalanceSheetGroupingTable" xml:lang="en-US">Fair Value, by Balance Sheet Grouping [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueByBalanceSheetGroupingTable" xlink:to="label_us-gaap_FairValueByBalanceSheetGroupingTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:label="locator_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xml:lang="en-US">Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems" xlink:to="label_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentsOwnedAtFairValueAbstract" xlink:label="locator_us-gaap_FinancialInstrumentsOwnedAtFairValueAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancialInstrumentsOwnedAtFairValueAbstract" xml:lang="en-US">Financial Instruments, Owned, at Fair Value [Abstract]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancialInstrumentsOwnedAtFairValueAbstract" xlink:to="label_us-gaap_FinancialInstrumentsOwnedAtFairValueAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract" xlink:label="locator_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract" xml:lang="en-US">Financial Assets:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract" xlink:to="label_us-gaap_FinancialInstrumentsFinancialAssetsBalanceSheetGroupingsAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LoansReceivableCarryingAmount" xlink:label="locator_sfst_LoansReceivableCarryingAmount"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LoansReceivableCarryingAmount" xml:lang="en-US">Loans, Carrying Amount</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_LoansReceivableCarryingAmount" xml:lang="en-US">Amount after allowance and deduction of deferred interest and fees, unamortized costs and premiums and discounts from face amounts, of loans and leases held in portfolio, including but not limited to, commercial and consumer loans. Includes loans held for sale. Excludes loans and leases covered under loss sharing agreements.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LoansReceivableCarryingAmount" xlink:to="label_sfst_LoansReceivableCarryingAmount"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsFairValueDisclosure" xlink:label="locator_us-gaap_OtherAssetsFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OtherAssetsFairValueDisclosure" xml:lang="en-US">Other investments, at cost, Fair Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OtherAssetsFairValueDisclosure" xlink:to="label_us-gaap_OtherAssetsFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LoansReceivableFairValueDisclosure" xlink:label="locator_us-gaap_LoansReceivableFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_LoansReceivableFairValueDisclosure" xml:lang="en-US">Loans, Fair Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_LoansReceivableFairValueDisclosure" xlink:to="label_us-gaap_LoansReceivableFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract" xlink:label="locator_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract" xml:lang="en-US">Financial Liabilities:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract" xlink:to="label_us-gaap_FinancialInstrumentsFinancialLiabilitiesBalanceSheetGroupingsAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FederalHomeLoanBankAdvances" xlink:label="locator_us-gaap_FederalHomeLoanBankAdvances"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FederalHomeLoanBankAdvances" xml:lang="en-US">FHLB and other borrowings, Carrying Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FederalHomeLoanBankAdvances" xlink:to="label_us-gaap_FederalHomeLoanBankAdvances"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubordinatedDebt" xlink:label="locator_us-gaap_SubordinatedDebt"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SubordinatedDebt" xml:lang="en-US">Junior subordinated debentures, Carrying Amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SubordinatedDebt" xlink:to="label_us-gaap_SubordinatedDebt"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DepositsFairValueDisclosure" xlink:label="locator_us-gaap_DepositsFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_DepositsFairValueDisclosure" xml:lang="en-US">Deposits, Fair Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_DepositsFairValueDisclosure" xlink:to="label_us-gaap_DepositsFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FederalHomeLoanBankBorrowingsFairValueDisclosure" xlink:label="locator_us-gaap_FederalHomeLoanBankBorrowingsFairValueDisclosure"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FederalHomeLoanBankBorrowingsFairValueDisclosure" xml:lang="en-US">FHLB and other borrowings, Fair Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FederalHomeLoanBankBorrowingsFairValueDisclosure" xlink:to="label_us-gaap_FederalHomeLoanBankBorrowingsFairValueDisclosure"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisSubordinatedDebtObligations" xlink:label="locator_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisSubordinatedDebtObligations"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisSubordinatedDebtObligations" xml:lang="en-US">Junior subordinated debentures, Fair Value</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisSubordinatedDebtObligations" xlink:to="label_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisSubordinatedDebtObligations"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_LeasesTextualAbstract" xlink:label="locator_sfst_LeasesTextualAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_LeasesTextualAbstract" xml:lang="en-US">Leases (Textual)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_LeasesTextualAbstract" xlink:to="label_sfst_LeasesTextualAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:label="locator_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xml:lang="en-US">Weighted average remaining life</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1" xlink:to="label_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent" xlink:label="locator_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent" xml:lang="en-US">Weighted average discount rate</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent" xlink:to="label_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseCost" xlink:label="locator_us-gaap_OperatingLeaseCost"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeaseCost" xml:lang="en-US">Operating lease costs</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeaseCost" xlink:to="label_us-gaap_OperatingLeaseCost"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset" xlink:label="locator_us-gaap_OperatingLeaseRightOfUseAsset"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeaseRightOfUseAsset" xml:lang="en-US">Operating lease, right-of-use asset</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeaseRightOfUseAsset" xlink:to="label_us-gaap_OperatingLeaseRightOfUseAsset"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiability" xlink:label="locator_us-gaap_OperatingLeaseLiability"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeaseLiability" xml:lang="en-US">Lease liabilities</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_OperatingLeaseLiability" xml:lang="en-US">Total lease liability</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeaseLiability" xlink:to="label_us-gaap_OperatingLeaseLiability"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ConsumerPriceIndexDescription" xlink:label="locator_sfst_ConsumerPriceIndexDescription"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ConsumerPriceIndexDescription" xml:lang="en-US">Consumer price index, description</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ConsumerPriceIndexDescription" xml:lang="en-US">The description related to consumer price index.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ConsumerPriceIndexDescription" xlink:to="label_sfst_ConsumerPriceIndexDescription"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent" xlink:label="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent" xml:lang="en-US">2021</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent" xlink:to="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueCurrent"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears" xlink:label="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears" xml:lang="en-US">2022</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears" xlink:to="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInTwoYears"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears" xlink:label="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears" xml:lang="en-US">2023</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears" xlink:to="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInThreeYears"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears" xlink:label="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears" xml:lang="en-US">2024</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears" xlink:to="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFourYears"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears" xlink:label="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears" xml:lang="en-US">2025</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears" xlink:to="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueInFiveYears"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter" xlink:label="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter" xml:lang="en-US">Thereafter</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter" xlink:to="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDueThereafter"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasesFutureMinimumPaymentsDue" xlink:label="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDue"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/totalLabel" xlink:label="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDue" xml:lang="en-US">Total undiscounted lease payments</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDue" xml:lang="en-US">Operating Leases, Future Minimum Payments Due</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_OperatingLeasesFutureMinimumPaymentsDue" xlink:to="label_us-gaap_OperatingLeasesFutureMinimumPaymentsDue"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_DiscountEffectOfCashFlows" xlink:label="locator_sfst_DiscountEffectOfCashFlows"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2009/role/negatedLabel" xlink:label="label_sfst_DiscountEffectOfCashFlows" xml:lang="en-US">Discount effect of cash flows</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_DiscountEffectOfCashFlows" xml:lang="en-US">The discount effect of cash flow.</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_DiscountEffectOfCashFlows" xml:lang="en-US">Discount Effect Of Cash Flows</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_DiscountEffectOfCashFlows" xlink:to="label_sfst_DiscountEffectOfCashFlows"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_EarningsPerCommonShareTextualAbstract" xlink:label="locator_sfst_EarningsPerCommonShareTextualAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_EarningsPerCommonShareTextualAbstract" xml:lang="en-US">Earnings Per Common Share (Textual)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_EarningsPerCommonShareTextualAbstract" xlink:to="label_sfst_EarningsPerCommonShareTextualAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:label="locator_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xml:lang="en-US">Antidilutive securities excluded from computation of earnings per share, amount</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount" xlink:to="label_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ComponentsOfEarningsPerShareAbstract" xlink:label="locator_sfst_ComponentsOfEarningsPerShareAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ComponentsOfEarningsPerShareAbstract" xml:lang="en-US">Schedule of earnings per share reconciliation</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_ComponentsOfEarningsPerShareAbstract" xml:lang="en-US">Components of earnings per share.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ComponentsOfEarningsPerShareAbstract" xlink:to="label_sfst_ComponentsOfEarningsPerShareAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_NumeratorOfEarningsPerShareAbstract" xlink:label="locator_sfst_NumeratorOfEarningsPerShareAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_NumeratorOfEarningsPerShareAbstract" xml:lang="en-US">Numerator:</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_NumeratorOfEarningsPerShareAbstract" xml:lang="en-US">Numerator of earnings per share</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_NumeratorOfEarningsPerShareAbstract" xlink:to="label_sfst_NumeratorOfEarningsPerShareAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:label="locator_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xml:lang="en-US">Net income available to common shareholders</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic" xlink:to="label_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_DenominatorOfEarningsPerShareAbstract" xlink:label="locator_sfst_DenominatorOfEarningsPerShareAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_DenominatorOfEarningsPerShareAbstract" xml:lang="en-US">Denominator:</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_DenominatorOfEarningsPerShareAbstract" xml:lang="en-US">Denominator of earnings per share.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_DenominatorOfEarningsPerShareAbstract" xlink:to="label_sfst_DenominatorOfEarningsPerShareAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:label="locator_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xml:lang="en-US">Common stock equivalents</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment" xlink:to="label_us-gaap_WeightedAverageNumberDilutedSharesOutstandingAdjustment"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareBasicAndDilutedAbstract" xlink:label="locator_us-gaap_EarningsPerShareBasicAndDilutedAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_EarningsPerShareBasicAndDilutedAbstract" xml:lang="en-US">Earnings per common share:</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_EarningsPerShareBasicAndDilutedAbstract" xlink:to="label_us-gaap_EarningsPerShareBasicAndDilutedAbstract"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_ReportableSegmentsTextualAbstract" xlink:label="locator_sfst_ReportableSegmentsTextualAbstract"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_ReportableSegmentsTextualAbstract" xml:lang="en-US">Reportable Segments (Textual)</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_ReportableSegmentsTextualAbstract" xlink:to="label_sfst_ReportableSegmentsTextualAbstract"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NumberOfReportableSegments" xlink:label="locator_us-gaap_NumberOfReportableSegments"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_NumberOfReportableSegments" xml:lang="en-US">Number of segments</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_NumberOfReportableSegments" xlink:to="label_us-gaap_NumberOfReportableSegments"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:label="locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xml:lang="en-US">Schedule of Segment Reporting Information, by Segment [Table]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable" xlink:to="label_us-gaap_ScheduleOfSegmentReportingInformationBySegmentTable"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementBusinessSegmentsAxis" xlink:label="locator_us-gaap_StatementBusinessSegmentsAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_StatementBusinessSegmentsAxis" xml:lang="en-US">Segments [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_StatementBusinessSegmentsAxis" xlink:to="label_us-gaap_StatementBusinessSegmentsAxis"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_CommercialAndRetailBankingMember" xlink:label="locator_sfst_CommercialAndRetailBankingMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_CommercialAndRetailBankingMember" xml:lang="en-US">Commercial And Retail Banking [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_CommercialAndRetailBankingMember" xml:lang="en-US">Commercial and reatail banking.</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_CommercialAndRetailBankingMember" xlink:to="label_sfst_CommercialAndRetailBankingMember"/>
    <loc xlink:type="locator" xlink:href="sfst-20210630.xsd#sfst_MortgageBankingSegmentMember" xlink:label="locator_sfst_MortgageBankingSegmentMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_sfst_MortgageBankingSegmentMember" xml:lang="en-US">Mortgage Banking [Member]</label>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/documentation" xlink:label="label_sfst_MortgageBankingSegmentMember" xml:lang="en-US">Mortgage Banking Segment [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_sfst_MortgageBankingSegmentMember" xlink:to="label_sfst_MortgageBankingSegmentMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CorporateMember" xlink:label="locator_us-gaap_CorporateMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_CorporateMember" xml:lang="en-US">Corporate Segment [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_CorporateMember" xlink:to="label_us-gaap_CorporateMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ConsolidationItemsAxis" xlink:label="locator_srt_ConsolidationItemsAxis"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_srt_ConsolidationItemsAxis" xml:lang="en-US">Consolidation Items [Axis]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_srt_ConsolidationItemsAxis" xlink:to="label_srt_ConsolidationItemsAxis"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IntersegmentEliminationMember" xlink:label="locator_us-gaap_IntersegmentEliminationMember"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_IntersegmentEliminationMember" xml:lang="en-US">Intersegment Eliminations [Member]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_IntersegmentEliminationMember" xlink:to="label_us-gaap_IntersegmentEliminationMember"/>
    <loc xlink:type="locator" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingInformationLineItems" xlink:label="locator_us-gaap_SegmentReportingInformationLineItems"/>
    <label xlink:type="resource" xlink:role="http://www.xbrl.org/2003/role/label" xlink:label="label_us-gaap_SegmentReportingInformationLineItems" xml:lang="en-US">Segment Reporting Information [Line Items]</label>
    <labelArc xlink:type="arc" xlink:arcrole="http://www.xbrl.org/2003/arcrole/concept-label" xlink:from="locator_us-gaap_SegmentReportingInformationLineItems" xlink:to="label_us-gaap_SegmentReportingInformationLineItems"/>
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