    <SEC-DOCUMENT>0001193125-26-193939-index.html : 20260430
    <SEC-HEADER>0001193125-26-193939.hdr.sgml : 20260430
    <ACCEPTANCE-DATETIME>20260430070334
    ACCESSION NUMBER:		0001193125-26-193939
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20251231
    FILED AS OF DATE:		20260430
    DATE AS OF CHANGE:		20260430
    EFFECTIVENESS DATE:		20260430

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Lexeo Therapeutics, Inc.
    		CENTRAL INDEX KEY:			0001907108
    		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				854012572
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-41855
    		FILM NUMBER:		26920011

    	BUSINESS ADDRESS:
    		STREET 1:		345 PARK AVENUE SOUTH
    		STREET 2:		FLOOR 6
    		CITY:			NEW YORK
    		STATE:			NY
    		ZIP:			10010
    		BUSINESS PHONE:		(212) 547-9879

    	MAIL ADDRESS:
    		STREET 1:		345 PARK AVENUE SOUTH
    		STREET 2:		FLOOR 6
    		CITY:			NEW YORK
    		STATE:			NY
    		ZIP:			10010
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>ars_10-k_2025.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: ars_10-k_2025.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>