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Share-Based Awards, Share Option Valuation (Details) - Stock Options [Member] - USD ($) $ / shares in Units, $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Mar. 31, 2018 | Mar. 31, 2017 | Dec. 31, 2017 | [1]
Stock Option Activity [Roll Forward] |  |  |  |
Outstanding at beginning of period (in shares) | [1] | 6,959,347 |  |
Granted (in shares) |  | 1,190,378 |  |
Forfeited (in shares) |  | (38,156) |  |
Outstanding at end of period (in shares) |  | 8,635,089 |  | 6,959,347
Options vested and exercisable at end of period (in shares) |  | 6,357,746 |  |
Weighted Average Exercise Price [Abstract] |  |  |  |
Outstanding at beginning of period (in dollars per share) | [1] | $ 1.06 |  |
Granted (in dollars per share) |  | 17.53 |  |
forfeited (in dollars per share) |  | 1.37 |  |
Outstanding at end of period (in dollars per share) |  | 3.58 |  | $ 1.06
Options vested and exercisable at end of period (in dollars per share) |  | $ 1.16 |  |
Weighted-Average Remaining Contractual Term [Abstract] |  |  |  |
Outstanding |  | 8 years 2 months 5 days |  | 8 years 2 months 1 day
Granted |  | 9 years 11 months 12 days |  |
Options vested and exercisable |  | 7 years 1 month 6 days |  |
Aggregate Intrinsic Value [Abstract] |  |  |  |
Outstanding |  | $ 130,983 |  | $ 27,175
Options vested and exercisable |  | $ 111,852 |  |
Inotek [Member] |  |  |  |
Stock Option Activity [Roll Forward] |  |  |  |
Assumed as part of merger (in shares) |  | 523,520 |  |
Weighted Average Exercise Price [Abstract] |  |  |  |
Assumed as part of merger (in dollars per share) |  | $ 2.31 |  |
Weighted-Average Remaining Contractual Term [Abstract] |  |  |  |
Assumed as part of merger |  | 7 years 6 months 11 days |  |
Employees and Directors [Member] |  |  |  |
Weighted-Average Assumptions [Abstract] |  |  |  |
Risk-free interest rate |  | 2.57% | 2.03% |
Expected term |  | 5 years 9 months 4 days | 5 years 10 months 10 days |
Expected volatility |  | 88.60% | 94.30% |
Expected dividend yield |  | 0.00% | 0.00% |
Exercise price |  | $ 17.52 | $ 1.21 |
Fair value of common stock |  | $ 17.52 | $ 1.21 |
Non-Employees [Member] |  |  |  |
Weighted-Average Assumptions [Abstract] |  |  |  |
Risk-free interest rate |  | 2.74% |  |
Expected term |  | 10 years |  |
Expected volatility |  | 83.79% |  |
Expected dividend yield |  | 0.00% |  |
Exercise price |  | $ 18.75 |  |
Fair value of common stock |  | $ 18.75 |  |
[1] | Effected by Exchange Ratio

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- Definition Weighted average remaining contractual term for option awards assumed in merger., in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days. + References No definition available. + Details
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