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Acquisition Accounting (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 3 Months Ended |
--- | --- | --- | ---
Jan. 04, 2018 | Mar. 31, 2018 | Mar. 31, 2017 | Dec. 31, 2017
Estimated Fair Values of Assets Acquired and Liabilities Assumed [Abstract] |  |  |  |
Goodwill |  | $ 30,815 |  | $ 0
Business Acquisition, Pro Forma Information, Nonrecurring Adjustment [Line Items] |  |  |  |
Share-based compensation expense |  | 5,382 | $ 99 |
Inotek [Member] |  |  |  |
Acquisition-date Fair Value of Consideration Transferred [Abstract] |  |  |  |
Number of shares issuable - consideration transferred (in shares) | 7,077,326 |  |  |
Price per share of Inotek common stock on acquisition date (in dollars per share) | $ 12.16 |  |  |
Total purchase price | $ 86,060 |  |  |
Estimated Fair Values of Assets Acquired and Liabilities Assumed [Abstract] |  |  |  |
Cash and cash equivalents | 76,348 |  |  |
Short-term investments | 21,292 |  |  |
Prepaid expense and other assets | 1,041 |  |  |
Property and equipment | 256 |  |  |
Deposits | 168 |  |  |
Goodwill | 30,815 |  |  |
Accounts payable and accrued expenses | (4,961) |  |  |
Convertible notes | (38,388) |  |  |
Unfavorable lease liability | (511) |  |  |
Net assets acquired | $ 86,060 |  |  |
Acquisition costs incurred |  | 132 |  |
Supplemental Unaudited Pro Forma Information [Abstract] |  |  |  |
Revenue |  | 0 | 0 |
Net loss |  | (15,998) | $ (15,670) |
Inotek [Member] | Restricted Stock Units [Member] |  |  |  |
Acquisition-date Fair Value of Consideration Transferred [Abstract] |  |  |  |
Number of shares issuable - consideration transferred (in shares) | 271,718 |  |  |
Inotek [Member] | Common Stock [Member] |  |  |  |
Acquisition-date Fair Value of Consideration Transferred [Abstract] |  |  |  |
Number of shares issuable - consideration transferred (in shares) | 6,805,608 |  |  |
Inotek [Member] | Acquisition-related Costs [Member] |  |  |  |
Business Acquisition, Pro Forma Information, Nonrecurring Adjustment [Line Items] |  |  |  |
Transaction costs |  | 4,512 |  |
Share-based compensation expense |  | 3,459 |  |
Severance and stay bonuses expenses |  | $ 1,622 |  |

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- Definition Number of shares of equity interests issued or issuable to acquire entity. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 30 -Section 50 -Paragraph 1 -Subparagraph (b)(4) -URI http://asc.fasb.org/extlink&oid=35744584&loc=d3e6927-128479 + Details
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- Definition Amount of currency on hand as well as demand deposits with banks or financial institutions, acquired at the acquisition date. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 20 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=84161108&loc=d3e4845-128472 + Details
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- Definition Amount of investments in debt and equity securities, including, but not limited to, held-to-maturity, trading and available-for-sale expected to be converted to cash, sold or exchanged within one year or the normal operating cycle, if longer, acquired at the acquisition date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 20 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=84161108&loc=d3e4845-128472 + Details
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- Definition Amount of asset related to consideration paid in advance for costs that provide economic benefits in future periods, and amount of other assets that are expected to be realized or consumed within one year or the normal operating cycle, if longer, acquired at the acquisition date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 20 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=84161108&loc=d3e4845-128472 + Details
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- Definition Amount of liabilities incurred for goods and services received that are used in an entity's business and related party payables, assumed at the acquisition date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 20 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=84161108&loc=d3e4845-128472 + Details
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- Definition Amount recognized as of the acquisition date for the identifiable assets acquired in excess of (less than) the aggregate liabilities assumed. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 55 -Paragraph 37 -URI http://asc.fasb.org/extlink&oid=84160947&loc=d3e2207-128464 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 20 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=84161108&loc=d3e4845-128472 + Details
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- Definition The amount of property, plant, and equipment recognized as of the acquisition date. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 20 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=84161108&loc=d3e4845-128472 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 805 -SubTopic 10 -Section 55 -Paragraph 37 -URI http://asc.fasb.org/extlink&oid=84160947&loc=d3e2207-128464 + Details
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- Definition Amount after accumulated impairment loss of an asset representing future economic benefits arising from other assets acquired in a business combination that are not individually identified and separately recognized. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 50 -Paragraph 1 -Subparagraph (a) -URI http://asc.fasb.org/extlink&oid=35741047&loc=d3e13816-109267 Reference 2: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 45 -Paragraph 1 -URI http://asc.fasb.org/extlink&oid=6388280&loc=d3e13770-109266 Reference 3: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 350 -SubTopic 20 -Section 45 -Paragraph 5 -URI http://asc.fasb.org/extlink&oid=77989000&loc=SL49117168-202975 + Details
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