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Summary of Significant Accounting Policies (Details) $ in Thousands | 3 Months Ended | 12 Months Ended |
--- | --- | --- | ---
Mar. 31, 2018 USD ($) Segment | Mar. 31, 2017 USD ($) | Dec. 31, 2017 USD ($) | Dec. 31, 2016 USD ($)
Restricted Cash [Abstract] |  |  |  |
Cash and cash equivalents | $ 171,136 |  | $ 18,142 |
Restricted cash | 208 |  | 207 |
Total | 171,344 | $ 27,360 | $ 18,349 | $ 9,665
Short-term Investments [Abstract] |  |  |  |
Realized gains (losses) on short-term investment | 0 | 0 |  |
Net unrealized gains on short-term investment | 10 | 0 |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Cost basis | 11,551 |  |  |
Unrealized gains | 10 |  |  |
Fair value | 11,561 |  |  |
Other than temporary impairment | 0 |  |  |
NYC Biotechnology Tax Credit Program [Abstract] |  |  |  |
Research and development incentive | $ 186 |  |  |
Research and development incentive receivable |  | $ 192 |  |
Income Taxes [Abstract] |  |  |  |
Federal corporate tax rate | 21.00% |  | 34.00% |
Segment Reporting [Abstract] |  |  |  |
Number of operating segments | Segment | 1 |  |  |
Maximum [Member] |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Estimated useful lives | 5 years |  |  |
Minimum [Member] |  |  |  |
Property, Plant and Equipment [Line Items] |  |  |  |
Estimated useful lives | 3 years |  |  |
Certificates of Deposit [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Cost basis | $ 1,546 |  |  |
Unrealized gains | 0 |  |  |
Fair value | 1,546 |  |  |
United States Treasury Securities [Member] |  |  |  |
Schedule of Available-for-sale Securities [Line Items] |  |  |  |
Cost basis | 10,005 |  |  |
Unrealized gains | 10 |  |  |
Fair value | $ 10,015 |  |  |

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