<SEC-DOCUMENT>0001171520-18-000067.txt : 20180208
<SEC-HEADER>0001171520-18-000067.hdr.sgml : 20180208
<ACCEPTANCE-DATETIME>20180208125814
ACCESSION NUMBER:		0001171520-18-000067
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20180208
DATE AS OF CHANGE:		20180208
GROUP MEMBERS:		HABIB KAIROUZ
GROUP MEMBERS:		JOSHUA RUCH
GROUP MEMBERS:		MARK LESCHLY
GROUP MEMBERS:		RHO CAPITAL PARTNERS VERWALTUNGS GMBH
GROUP MEMBERS:		RHO MANAGEMENT VENTURES IV, L.L.C.
GROUP MEMBERS:		RHO VENTURES IV GMBH & CO BETEILIGUNGS KG
GROUP MEMBERS:		RHO VENTURES IV HOLDINGS LLC
GROUP MEMBERS:		RHO VENTURES IV QP, L.P.
GROUP MEMBERS:		RHO VENTURES IV, L.P.

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ROCKET PHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0001281895
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-88750
		FILM NUMBER:		18584614

	BUSINESS ADDRESS:	
		STREET 1:		430 EAST 29TH STREET
		STREET 2:		SUITE 1040
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10016
		BUSINESS PHONE:		646-440-9100

	MAIL ADDRESS:	
		STREET 1:		430 EAST 29TH STREET
		STREET 2:		SUITE 1040
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10016

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	INOTEK PHARMACEUTICALS CORP
		DATE OF NAME CHANGE:	20040226

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			RHO VENTURES IV QP LP
		CENTRAL INDEX KEY:			0001126022
		IRS NUMBER:				061581537
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		124 DUNE ROAD
		CITY:			QUOGUE
		STATE:			NY
		ZIP:			11959

	MAIL ADDRESS:	
		STREET 1:		124 DUNE RD
		CITY:			QUOGUE
		STATE:			NY
		ZIP:			11959
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>eps7754.htm
<TEXT>
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<P STYLE="margin: 0"></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><B>UNITED STATES</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><B>SECURITIES AND EXCHANGE COMMISSION</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><B>Washington, D.C. 20549</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-align: center"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-align: center"><B>SCHEDULE 13G</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><B>Under the Securities Exchange Act of 1934</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-align: center"><B>(Amendment No. 1 )*</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-align: center"><B>&nbsp;</B></P>


<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt"></P>

<P STYLE="font: 14pt Times New Roman,serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>Inotek pharmaceuticals
corporation</B></FONT></P>

<!-- Field: Rule-Page --><DIV ALIGN="CENTER" STYLE="margin-top: 3pt; margin-bottom: 3pt"><DIV STYLE="font-size: 1pt; border-top: Black 1pt solid; width: 100%">&nbsp;</DIV></DIV><!-- Field: /Rule-Page -->

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"></FONT></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-align: center">(Name of Issuer)</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center; border-bottom: Black 0.5pt solid"><FONT STYLE="text-transform: uppercase"><B>COMMON
STOCK, $0.01 PAR VALUE PER SHARE</B></FONT></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase">(T</FONT>itle
and Class of Securities)</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase">&nbsp;</FONT></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><FONT STYLE="text-transform: uppercase"><B>45780V102</B></FONT></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-align: center; border-top: Black 0.5pt solid">(CUSIP number)</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center; border-bottom: Black 0.5pt solid"><B>December 31, 2017</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">(Date of Event which Requires Filing of this Statement)</P>



<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt"></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">Check the appropriate box to designate the rule pursuant to which
this Schedule is filed:</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse; font-size: 11pt; margin-left: 0.5in">
<TR STYLE="vertical-align: top">
    <TD STYLE="width: 5%; font-family: Calibri,sans-serif"><FONT STYLE="font-family: MS Mincho; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="width: 95%; font-family: Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">Rule 13d-1(b)</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-family: Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="font-family: Calibri,sans-serif">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-family: Calibri,sans-serif"><FONT STYLE="font-family: MS Mincho; font-size: 10pt">&#9744;</FONT></TD>
    <TD STYLE="font-family: Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">Rule 13d-1(c)</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-family: Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="font-family: Calibri,sans-serif">&nbsp;</TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="font-family: Calibri,sans-serif"><FONT STYLE="font-family: MS Mincho; font-size: 10pt">&#9745;</FONT></TD>
    <TD STYLE="font-family: Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">Rule 13d-1(d)</FONT></TD></TR>
</TABLE>
<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-align: justify">________________________________</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">*The remainder of this cover page shall be filled out for a reporting person&rsquo;s
initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information
which would alter the disclosures provided in a prior cover page.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin-right: 0; margin-left: 0">The information required in the remainder of this
cover page shall not be deemed to be &ldquo;filed&rdquo; for the purpose of Section 18 of the Securities Exchange Act of 1934 (&ldquo;Act&rdquo;)
or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however,
<I>see</I> the <I>Notes</I>).</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Rho Ventures IV (QP), L.P.</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0"><FONT STYLE="font-family: Times New Roman,serif">(b) </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT>
        <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">Delaware</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">PN</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman,serif; margin: 0 0 10pt">(1) This Amendment No. 1 to the statement on Schedule 13G is filed
by Rho Ventures IV, L.P. (&ldquo;RV IV&rdquo;), Rho Ventures IV GmbH &amp; Co. Beteiligungs KG (&ldquo;RV KG&rdquo;), Rho Ventures
IV (QP), L.P. (&ldquo;RV QP&rdquo;), Rho Ventures IV Holdings LLC (&ldquo;RV IV Holdings&rdquo;), Rho Management Ventures IV, L.L.C.
(&ldquo;RMV&rdquo;), Rho Capital Partners Verwaltungs GmbH (&ldquo;RCP GmbH&rdquo;), Joshua Ruch (&ldquo;Ruch&rdquo;), Habib Kairouz
(&ldquo;Kairouz&rdquo;) and Mark Leschly (&ldquo;Leschly,&rdquo; together with RV IV, RV KG, RV QP, RV IV Holdings, RMV, RCP GmbH,
Ruch and Kairouz, collectively, the &ldquo;Reporting Persons&rdquo;). The Reporting Persons expressly disclaim status as a &ldquo;group&rdquo;
for purposes of this Schedule 13G.</P>


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<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 10pt"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Rho Ventures IV, L.P.</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
        (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 5in; text-indent: -5in"><FONT STYLE="font-family: Times New Roman,serif">(b)
        </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT> <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 34.5pt">Delaware</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">PN</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 10pt Times New Roman,serif; margin: 0">(1) This statement on Schedule 13G is filed by the Reporting Persons. The
Reporting Persons expressly disclaim status as a &ldquo;group&rdquo; for purposes of this Schedule 13G.</P>

<P STYLE="font: 10pt Times New Roman,serif; margin: 0">&nbsp;</P>


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<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 10pt"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Rho Ventures IV GmbH &amp; Co. Beteiligungs KG</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
        (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 5in; text-indent: -5in"><FONT STYLE="font-family: Times New Roman,serif">(b)
        </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT> <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 34.5pt">Delaware</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">OO</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman,serif; margin: 0">(1) This statement on Schedule 13G is filed by the Reporting Persons. The
Reporting Persons expressly disclaim status as a &ldquo;group&rdquo; for purposes of this Schedule 13G.</P>

<P STYLE="font: 10pt Times New Roman,serif; margin: 0">&nbsp;</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Rho Ventures IV Holdings LLC</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
        (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 5in; text-indent: -5in"><FONT STYLE="font-family: Times New Roman,serif">(b)
        </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT> <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 34.5pt">Delaware</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">OO</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman,serif; margin: 0">(1) This statement on Schedule 13G is filed by the Reporting Persons. The
Reporting Persons expressly disclaim status as a &ldquo;group&rdquo; for purposes of this Schedule 13G.</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Rho Management Ventures IV, L.L.C.</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
        (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 5in; text-indent: -5in"><FONT STYLE="font-family: Times New Roman,serif">(b)
        </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT> <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 34.5pt">Delaware</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">OO</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman,serif; margin: 0">(1) This statement on Schedule 13G is filed by the Reporting Persons. The
Reporting Persons expressly disclaim status as a &ldquo;group&rdquo; for purposes of this Schedule 13G.</P>

<P STYLE="font: 10pt Times New Roman,serif; margin: 0">&nbsp;</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Rho Capital Partners Verwaltungs GmbH</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
        (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 5in; text-indent: -5in"><FONT STYLE="font-family: Times New Roman,serif">(b)
        </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT> <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 34.5pt">Delaware</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">OO</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman,serif; margin: 0">(1) This statement on Schedule 13G is filed by the Reporting Persons. The
Reporting Persons expressly disclaim status as a &ldquo;group&rdquo; for purposes of this Schedule 13G.</P>

<P STYLE="font: 10pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Joshua Ruch</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
        (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 5in; text-indent: -5in"><FONT STYLE="font-family: Times New Roman,serif">(b)
        </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT> <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 34.5pt">United States</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">IN</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman,serif; margin: 0">(1) This statement on Schedule 13G is filed by the Reporting Persons. The
Reporting Persons expressly disclaim status as a &ldquo;group&rdquo; for purposes of this Schedule 13G.</P>

<P STYLE="font: 10pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>


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<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 10pt"></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><BR STYLE="clear: both">
<FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Mark Leschly</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
        (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 5in; text-indent: -5in"><FONT STYLE="font-family: Times New Roman,serif">(b)
        </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT> <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 34.5pt">Kingdom of Denmark</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0--</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">IN</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman,serif; margin: 0">(1) This statement on Schedule 13G is filed by the Reporting Persons. The
Reporting Persons expressly disclaim status as a &ldquo;group&rdquo; for purposes of this Schedule 13G.</P>

<P STYLE="font: 10pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; border-collapse: collapse">
<TR STYLE="vertical-align: top">
    <TD STYLE="border: black 1pt solid; font: 11pt Calibri,sans-serif"><BR STYLE="clear: both">
<FONT STYLE="font-family: Times New Roman,serif">1.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-top: black 1pt solid; border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">NAMES OF REPORTING PERSONS</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">Habib Kairouz</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">2.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP
        (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 5in; text-indent: -5in">(a) &#9744;</P>
        <P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 5in; text-indent: -5in"><FONT STYLE="font-family: Times New Roman,serif">(b)
        </FONT><FONT STYLE="font-family: Wingdings; font-size: 10pt">&thorn;</FONT> <FONT STYLE="font-family: Times New Roman,serif; font-size: 10pt">(1)</FONT></P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">3.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SEC USE ONLY</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">4.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">CITIZENSHIP OR PLACE OF ORGANIZATION</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 34.5pt">United States</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD COLSPAN="2" ROWSPAN="4" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING
        PERSON WITH</P></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">5.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE VOTING POWER&nbsp;&nbsp;&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">6.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED VOTING POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">7.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SOLE DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">8.</FONT></TD>
    <TD STYLE="border-right: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">SHARED DISPOSITIVE POWER&nbsp;&nbsp;&nbsp;--0-- </FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">9.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">--0--</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">10.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES&nbsp;&nbsp;(SEE INSTRUCTIONS)&nbsp;&nbsp;&#9744;</FONT></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">11.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0">PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW 9</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">0%</P></TD></TR>
<TR STYLE="vertical-align: top">
    <TD STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid; border-left: black 1pt solid; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">12.</FONT></TD>
    <TD COLSPAN="3" STYLE="border-right: black 1pt solid; border-bottom: black 1pt solid">
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)</P>
        <P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt; text-indent: 0.5in">IN</P></TD></TR>
<TR>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 14%">&nbsp;</TD>
    <TD STYLE="width: 5%">&nbsp;</TD>
    <TD STYLE="width: 76%">&nbsp;</TD></TR>
</TABLE>
<P STYLE="font: 10pt Times New Roman,serif; margin: 0">(1) This statement on Schedule 13G is filed by the Reporting Persons. The
Reporting Persons expressly disclaim status as a &ldquo;group&rdquo; for purposes of this Schedule 13G.</P>

<P STYLE="font: 10pt Times New Roman,serif; margin: 0">&nbsp;</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0">Introductory Note: This Amendment No. 1 to the statement on Schedule 13G
is filed by the Reporting Persons in respect of shares of Common Stock, par value $0.001 per share, of Inotek Pharmaceuticals Corporation.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 1(a).</B></TD><TD><B>Name of Issuer:</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 0.5in; text-indent: 0.5in">Inotek Pharmaceuticals Corporation (the &ldquo;Issuer&rdquo;).</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 1(b).</B></TD><TD><B>Address of Issuer&rsquo;s Principal Executive Offices:</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 0.5in; text-indent: 0.5in">91 Hartwell Avenue, Lexington, MA 02421</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(a).</B></TD><TD><B>Name of Person Filing:</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 0.5in; text-indent: 0.5in">This statement is filed by:</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(i)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Rho Ventures IV (QP), L.P. (&ldquo;RV QP&rdquo;)</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(ii)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Rho Ventures IV, L.P. (&ldquo;RV IV&rdquo;)</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(iii)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Rho Ventures IV GmbH &amp; Co. Beteiligungs KG (&ldquo;RV KG&rdquo;)</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(iv)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Rho Ventures IV Holdings LLC (&ldquo;RV IV Holdings&rdquo;)</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(v)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Rho Management Ventures IV, L.L.C. (&ldquo;RMV&rdquo;)</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(vi)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Rho Capital Partners Verwaltungs GmbH (&ldquo;RCP GmbH&rdquo;)</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(vii)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Joshua Ruch (&ldquo;Ruch&rdquo;)</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(viii)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Mark Leschly (&ldquo;Leschly&rdquo;)</FONT></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Calibri,sans-serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 1in"></TD><TD STYLE="width: 0.5in"><FONT STYLE="font-family: Times New Roman,serif">(ix)</FONT></TD><TD><FONT STYLE="font-family: Times New Roman,serif">Habib Kairouz (&ldquo;Kairouz&rdquo;)</FONT></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">RV QP, RV IV, RV KG, RV IV Holdings, RMV, RCP GmbH,
Ruch, Leschly and Kairouz are sometimes individually referred to herein as a &ldquo;Reporting Person&rdquo; and collectively as
the &ldquo;Reporting Persons.&rdquo;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(b).</B></TD><TD><B>Address of Principal Business Office or, if None, Residence:</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 1in">Rho Ventures, 152 W 57th Street, 23rd Floor, New York,
New York 10019</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(c).</B></TD><TD><B>Citizenship:</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLSPACING="0" CELLPADDING="0" STYLE="width: 100%; margin-left: 1in">
<TR>
    <TD STYLE="vertical-align: top; width: 26%; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">RV QP </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; width: 72%; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Delaware</FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">RV IV </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Delaware</FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">RV KG </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Germany</FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">RV IV Holdings </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Delaware</FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">RMV </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Delaware</FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">RCP GmbH </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Germany</FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Ruch </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">United States</FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Leschly </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Kingdom of Denmark</FONT></TD></TR>
<TR>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">Kairouz </FONT></TD>
    <TD STYLE="vertical-align: bottom; font: 11pt Calibri,sans-serif">&nbsp;</TD>
    <TD STYLE="vertical-align: top; font: 11pt Calibri,sans-serif"><FONT STYLE="font-family: Times New Roman,serif">United States</FONT></TD></TR>
</TABLE>
<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(d).</B></TD><TD><B>Title of Class of Securities:</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 1in">Common Stock, $0.01 par value per share (the &ldquo;Common
Stock&rdquo;)</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 0"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 2(e).</B></TD><TD><B>CUSIP Number:</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 0.5in; text-indent: 0.5in"><FONT STYLE="text-transform: uppercase">45780V102</FONT></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in; text-indent: -1in"><B>&nbsp;</B></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 3.</B></TD><TD>If this statement is filed pursuant to Rules 13d-1(b) or 13d-2(b) or (c), check whether the person filing is a:</TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(a) |_| Broker or dealer registered under Section 15 of the Act,</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(b) |_| Bank as defined in Section 3(a)(6) of the Act,</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(c) |_| Insurance Company as defined in Section 3(a)(19) of the
Act,</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(d) |_| Investment Company registered under Section 8 of the Investment
Company Act of 1940,</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(e) |_| Investment Adviser in accordance with Rule 13d-1(b)(1)(ii)(E),</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(f) |_| Employee Benefit Plan or Endowment Fund in accordance
with 13d-1 (b)(1)(ii)(F),</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(g) |_| Parent Holding Company or control person in accordance
with Rule 13d-1 (b)(1)(ii)(G),</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(h) |_| Savings Association as defined in Section 3(b) of the
Federal Deposit Insurance Act,</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 1in">(i) |_| Church Plan that is excluded from the definition of an
investment company under Section 3(c)(14) of the Investment Company Act of 1940,</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">(j) |_| Group, in accordance with Rule 13d-1(b)(1)(ii)(J).</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1.5in; text-indent: -1in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 4a.</B></TD><TD><B>Amount Beneficially Owned: 0</B></TD></TR></TABLE>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item&nbsp;4(b)</B></TD><TD><B>Percent of Class: 0%</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item&nbsp;4(c)</B></TD><TD><B>Number of shares as to which such persons have:</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">(i)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;sole power to vote
or to direct the vote: 0</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">(ii)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;shared power to vote
or to direct the vote: 0</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">(iii)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;sole power to dispose
or to direct the disposition of: 0</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">(iv)&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;shared power to dispose
or to direct the disposition of: 0</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 5.</B></TD><TD><B>Ownership of Five Percent or Less of a Class.</B></TD></TR></TABLE>

<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 0 1in"><FONT STYLE="font-family: Times New Roman,serif">If this statement
is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more
than 5% of the class of securities, check the following: </FONT><FONT STYLE="font-family: Segoe UI Symbol,sans-serif">&#9745;</FONT></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 6.</B></TD><TD><B>Ownership of More than Five Percent on Behalf of Another Person.</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">Not applicable.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 7.</B></TD><TD><B>Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding
Company.</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">Not applicable.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 8.</B></TD><TD><B>Identification and Classification of Members of the Group.</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">Not applicable.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 1in">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 9.</B></TD><TD><B>Notice of Dissolution of Group.</B></TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 1in">Not applicable.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<TABLE CELLPADDING="0" CELLSPACING="0" WIDTH="100%" STYLE="font: 11pt Times New Roman,serif; margin-top: 0; margin-bottom: 6pt"><TR STYLE="vertical-align: top">
<TD STYLE="width: 0"></TD><TD STYLE="width: 1in"><B>Item 10.</B></TD><TD><B>Certification</B>.</TD></TR></TABLE>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 1in">Not applicable.</P>



<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B></B></P>





<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center"><B>SIGNATURES</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">After reasonable inquiry and to the best of his, her
or its knowledge and belief, each of the persons signing below certifies that the information set forth in this statement is true,
complete and correct.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-indent: 0.5in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">Dated: February 8, 2018</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in"><B>Rho Ventures IV (QP), L.P.</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: Rho Management Ventures IV, L.L.C.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Ventures IV, L.P.</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: Rho Management Ventures IV, L.L.C.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Ventures IV GmbH &amp; Co. Beteiligungs KG </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 2.5in; text-indent: 0.5in">By: Rho Capital Partners Verwaltungs GmbH</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Ventures IV Holdings LLC </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Management Ventures IV, L.L.C. </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Capital Partners Verwaltungs GmbH </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Joshua Ruch </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Mark Leschly </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in"><B>Habib Kairouz</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">EXHIBIT INDEX</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: center">&nbsp;</P>

<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Exhibit 1:
&#9;Joint Filing Statement</FONT></P>

<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Exhibit 2:
&#9;Power of Attorney</FONT></P>


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    <DIV STYLE="page-break-before: always; margin-top: 6pt; margin-bottom: 12pt">&nbsp;</DIV>
    <!-- Field: /Page -->


<P STYLE="font: 11pt Calibri,sans-serif; margin: 0; text-align: right">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: right"><B><U>Exhibit 1</U></B></P>

<P STYLE="font: 10.5pt Calibri,sans-serif; margin: 0 0 10pt; text-align: center"><FONT STYLE="font-family: Times New Roman, Times, Serif"><B>AGREEMENT</B></FONT></P>

<P STYLE="font: 10.5pt Calibri,sans-serif; margin: 0 36.9pt 10pt 4.5pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">&nbsp;</FONT></P>

<P STYLE="font: 10.5pt Calibri,sans-serif; margin: 0 0 10pt; text-align: justify"><FONT STYLE="font-family: Times New Roman, Times, Serif">Pursuant
to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, the undersigned hereby agree that only one statement
containing the information required by Schedule 13G need be filed with respect to the ownership by each of the undersigned of
the shares of Common Stock of Inotek Pharmaceuticals Corporation.</FONT></P>

<P STYLE="font: 10.5pt Calibri,sans-serif; margin: 0 0 10pt; text-align: justify">&nbsp;</P>

<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 10pt"><FONT STYLE="font-family: Times New Roman, Times, Serif">Dated: February
6, 2018</FONT></P>

<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 10pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in"><B>Rho Ventures IV (QP), L.P.</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: Rho Management Ventures IV, L.L.C.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Ventures IV, L.P.</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: Rho Management Ventures IV, L.L.C.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Ventures IV GmbH &amp; Co. Beteiligungs KG </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 2.5in; text-indent: 0.5in">By: Rho Capital Partners Verwaltungs GmbH</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Ventures IV Holdings LLC </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Management Ventures IV, L.L.C. </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Rho Capital Partners Verwaltungs GmbH </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Joshua Ruch </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in"><B>Mark Leschly </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in"><B>Habib Kairouz</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3in">By: <U>/s/ Peter Kalkanis</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 0 3.25in">Name: Peter Kalkanis</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt 3.25in">Title: Authorized Signatory</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0; text-align: right"><U>Exhibit 2</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt"><B>POWER OF ATTORNEY</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt">The undersigned hereby constitutes and appoints Peter Kalkanis, with
full power of substitution, as the undersigned's true and lawful attorney-in-fact to:</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt">(1) prepare, execute in the undersigned's name and on the undersigned's
behalf, and submit to the U.S. Securities and Exchange Commission (the &quot;SEC&quot;) a Form ID, including amendments thereto,
and any other documents necessary or appropriate to obtain codes and passwords enabling the undersigned to make electronic filings
with the SEC of reports required by Section 16(a) of the Securities Exchange Act of 1934 or any rule or regulation of the SEC;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt">(2) execute for and on behalf of the undersigned, in the undersigned's
capacity as an officer and/or director of Inotek Pharmaceutical Corporation (the &quot;Company&quot;) and/or 5% or 10% holder of
the Company's capital stock, Forms 3, 4, and 5 as well as any Section 13D or 13G filings and any amendments thereto in accordance
with Sections 13 and 16(a) of the Securities Exchange Act of 1934 and the rules thereunder;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt">(3) do and perform any and all acts for and on behalf of the undersigned
which may be necessary or desirable to complete and execute any such Form 3, 4, or 5, 13D or 13G, complete and execute any amendment
or amendments thereto, and timely file such form with the SEC and any stock exchange or similar authority; and</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt">(4) take any other action of any type whatsoever in connection with
the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required
by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant
to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve
in such attorney-in-fact's discretion.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt">The undersigned hereby grants to each such attorney-in-fact full
power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the
exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could
do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that such attorney-in-fact,
or such attorney-in-fact's substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney
and the rights and powers herein granted. The undersigned acknowledges that the foregoing attorneys-in-fact, in serving in such
capacity at the request of the undersigned, are not assuming, nor is the Company assuming, any of the undersigned's responsibilities
to comply with Sections 13 or 16 of the Securities Exchange Act of 1934.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt">This Power of Attorney shall remain in full force and effect until
the undersigned is no longer required to file Forms 3, 4, and 5, 13D or 13G with respect to the undersigned's holdings of and transactions
in securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to the foregoing attorneys-in-fact.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 12pt">IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney
to be executed as of this 5th day of February, 2018.</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>Rho Ventures IV (QP), L.P.</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: Rho Management Ventures IV, L.L.C.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: <U>/s/ Habib Kairouz</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">Name: Habib Kairouz</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Title: Managing Member</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt"><B>Rho Ventures IV, L.P.</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: Rho Management Ventures IV, L.L.C.</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: <U>/s/ Habib Kairouz</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">Name: Habib Kairouz</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Title: Managing Member</P>

<P STYLE="font: 11pt Calibri,sans-serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt"><B>Rho Ventures IV GmbH &amp; Co. Beteiligungs KG </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: Rho Capital Partners Verwaltungs GmbH</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Its: General Partner</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: <U>/s/ Habib Kairouz</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">Name: Habib Kairouz</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Title: Managing Member</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt"><B>Rho Ventures IV Holdings LLC </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">By: Rho Management Ventures IV, L.L.C., its Managing Member</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: <U>/s/ Habib Kairouz</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">Name: Habib Kairouz</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Title: Managing Member</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt"><B>Rho Management Ventures IV, L.L.C. </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: <U>/s/ Habib Kairouz</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">Name: Habib Kairouz</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Title: Managing Member</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">&nbsp;</P>


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<P STYLE="font: 11pt Times New Roman,serif; margin: 0"><B>&nbsp;</B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt"><B>Rho Capital Partners Verwaltungs GmbH </B></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">By: <U>/s/ Habib Kairouz</U></P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0">Name: Habib Kairouz</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 6pt">Title: Managing Member</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt"><U>/s/ Habib Kairouz</U><BR>
Habib Kairouz</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt"><U>/s/ Joshua Ruch</U><BR>
Joshua Ruch</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt">&nbsp;</P>

<P STYLE="font: 11pt Times New Roman,serif; margin: 0 0 10pt"><U>/s/ Mark Leschly</U><BR>
Mark Leschly</P>



<P STYLE="margin: 0"></P>

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