<SEC-DOCUMENT>0001104659-22-021208-index.html : 20220214
<SEC-HEADER>0001104659-22-021208.hdr.sgml : 20220214
<ACCEPTANCE-DATETIME>20220214061947
ACCESSION NUMBER:		0001104659-22-021208
CONFORMED SUBMISSION TYPE:	SC 13G/A
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20220214
DATE AS OF CHANGE:		20220214
GROUP MEMBERS:		CITADEL ADVISORS HOLDINGS LP
GROUP MEMBERS:		CITADEL GP LLC
GROUP MEMBERS:		CITADEL SECURITIES GP LLC
GROUP MEMBERS:		CITADEL SECURITIES GROUP LP
GROUP MEMBERS:		CITADEL SECURITIES LLC
GROUP MEMBERS:		KENNETH GRIFFIN

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Annexon, Inc.
		CENTRAL INDEX KEY:			0001528115
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				275414423
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91583
		FILM NUMBER:		22624697

	BUSINESS ADDRESS:	
		STREET 1:		1400 SIERRA POINT PARKWAY
		STREET 2:		BLDG C SUITE 200
		CITY:			BRISBANE
		STATE:			CA
		ZIP:			94005
		BUSINESS PHONE:		(650)-822-5500

	MAIL ADDRESS:	
		STREET 1:		1400 SIERRA POINT PARKWAY
		STREET 2:		BLDG C SUITE 200
		CITY:			BRISBANE
		STATE:			CA
		ZIP:			94005

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CITADEL ADVISORS LLC
		CENTRAL INDEX KEY:			0001423053
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13G/A

	BUSINESS ADDRESS:	
		STREET 1:		131 S. DEARBORN ST., 32ND FLOOR
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60603
		BUSINESS PHONE:		312-395-2100

	MAIL ADDRESS:	
		STREET 1:		131 S. DEARBORN ST., 32ND FLOOR
		CITY:			CHICAGO
		STATE:			IL
		ZIP:			60603
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13G/A
<SEQUENCE>1
<FILENAME>tm223994d3_sc13ga.htm
<DESCRIPTION>ANNEXON, INC.
<TEXT>
Document 1 - file: tm223994d3_sc13ga.htm

</DOCUMENT>
</SEC-DOCUMENT>