    <SEC-DOCUMENT>0001140361-22-016231-index.html : 20220427
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    ACCESSION NUMBER:		0001140361-22-016231
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		4
    CONFORMED PERIOD OF REPORT:	20220609
    FILED AS OF DATE:		20220427
    DATE AS OF CHANGE:		20220427

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Annexon, Inc.
    		CENTRAL INDEX KEY:			0001528115
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				275414423
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-39402
    		FILM NUMBER:		22859721

    	BUSINESS ADDRESS:
    		STREET 1:		1400 SIERRA POINT PARKWAY
    		STREET 2:		BLDG C SUITE 200
    		CITY:			BRISBANE
    		STATE:			CA
    		ZIP:			94005
    		BUSINESS PHONE:		(650)-822-5500

    	MAIL ADDRESS:
    		STREET 1:		1400 SIERRA POINT PARKWAY
    		STREET 2:		BLDG C SUITE 200
    		CITY:			BRISBANE
    		STATE:			CA
    		ZIP:			94005
    </SEC-HEADER>
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    <TYPE>DEF 14A
    <SEQUENCE>1
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    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: edge20003421x1_def14a.htm

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    <TEXT>
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    <SEQUENCE>3
    <FILENAME>edge20003421x1_pc02.jpg
    <TEXT>
    Document 3 - file: edge20003421x1_pc02.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>sig_douglaslove.jpg
    <TEXT>
    Document 4 - file: sig_douglaslove.jpg

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