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v3.23.3

Condensed Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 9 Months Ended
--- | ---
Sep. 30, 2023 | Sep. 30, 2022
Operating activities: |  |
Net loss | $ (106,346) | $ (107,564)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 1,610 | 1,576
Accretion of (discount) premium on available-for-sale securities | (2,290) | 490
Stock-based compensation | 13,816 | 13,683
Reduction in the carrying amount of right-of-use assets | 823 | 717
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 1,543 | (280)
Other assets |  | (204)
Accounts payable | (2,503) | (777)
Accrued liabilities | (2,958) | 4,041
Operating lease liabilities | (1,350) | (883)
Other current liabilities | (10) | 31
Net cash used in operating activities | (97,665) | (89,170)
Investing activities: |  |
Purchases of property and equipment | (186) | (6,244)
Purchases of available-for-sale securities | (83,612) | (46,364)
Proceeds from maturities of available-for-sale securities | 156,684 | 154,666
Net cash provided by investing activities | 72,886 | 102,058
Financing activities: |  |
Proceeds from the exercise of common stock options | 111 | 64
Proceeds from Employee Stock Purchase Plan purchases | 345 | 113
Proceeds from the issuance of common stock to a related party, net of commissions | 17,545 |
Payment of common stock issuance costs | (75) |
Proceeds from the issuance of common stock, pre-funded warrants and common warrants in private placement |  | 120,976
Proceeds from the issuance of common stock, pre-funded warrants and common warrants in private placement - related party |  | 9,500
Payment of common stock, pre-funded warrants and common warrants issuance costs related to private placement |  | (7,853)
Net cash provided by financing activities | 17,926 | 122,800
(Decrease) increase in cash, cash equivalents and restricted cash | (6,853) | 135,688
Effect of exchange rate changes on cash, cash equivalents and restricted cash | (8) | (7)
Cash, cash equivalents and restricted cash |  |
Beginning of period | 141,052 | 76,009
End of period | 134,191 | 211,690
Supplemental disclosure of cash flow information: |  |
Cash paid for amounts included in the measurement of lease liability | 3,525 | 3,028
Non-cash investing and financing activities: |  |
Purchases of property and equipment included in accounts payable and accrued liabilities | $ 6 | $ 118

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