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v3.24.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2023 | Dec. 31, 2022
Operating activities: |  |
Net loss | $ (134,237) | $ (141,947)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 2,148 | 2,106
Accretion of (discount) premium on available-for-sale securities | (2,550) | 73
Stock-based compensation | 18,183 | 18,516
Reduction in the carrying amount of right-of-use assets | 1,119 | 1,205
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 1,352 | (463)
Accounts payable | (2,077) | (287)
Accrued liabilities | (3,438) | 6,178
Operating lease liabilities | (1,503) | (1,731)
Other current liabilities | (139) | 41
Net cash used in operating activities | (121,142) | (116,309)
Investing activities: |  |
Purchases of property and equipment | (193) | (6,526)
Purchases of available-for-sale securities | (108,088) | (113,197)
Proceeds from maturities of available-for-sale securities | 178,984 | 178,166
Net cash provided by investing activities | 70,703 | 58,443
Financing activities: |  |
Proceeds from the exercise of common stock options | 90 | 80
Proceeds from Employee Stock Purchase Plan purchases | 479 | 340
Proceeds from the issuance of common stock, pre-funded warrants and common warrants, including related party of $17,995 and $9,500 for the years ended December 31, 2023 and 2022, respectively | 17,995 | 130,476
Proceeds from the issuance of common stock, pre-funded warrants and common warrants, including related party of $948, net of commissions | 117,515 |
Payment of financing costs | (555) | (7,988)
Net cash provided by financing activities | 135,524 | 122,908
Increase in cash, cash equivalents and restricted cash | 85,085 | 65,042
Effect of exchange rate changes on cash, cash equivalents and restricted cash | 5 | 1
Cash, cash equivalents and restricted cash |  |
Beginning of period | 141,052 | 76,009
End of period | 226,142 | 141,052
Supplemental disclosure of cash flow information: |  |
Cash paid for amounts included in the measurement of lease liability | 4,728 | 10,078
Non-cash investing and financing activities: |  |
Deferred offering costs included in accounts payable and accrued liabilities | $ 483 |
Purchases of property and equipment included in accounts payable and accrued liabilities |  | $ 110

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