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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Total
Related Party [Member]
Pre-Funded Warrants [Member]
Pre-Funded Warrants and Common Warrants [Member]
Common Stock [Member]
Common Stock [Member]
Related Party [Member]
Common Stock [Member]
Pre-Funded Warrants [Member]
Common Stock [Member]
Pre-Funded Warrants and Common Warrants [Member]
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Related Party [Member]
Additional Paid-in Capital [Member]
Pre-Funded Warrants [Member]
Additional Paid-in Capital [Member]
Pre-Funded Warrants and Common Warrants [Member]
Accumulated Other Comprehensive Loss [Member]
Accumulated Deficit [Member]
Beginning Balance, Values at Dec. 31, 2021 $ 231,909       $ 39       $ 528,365       $ (180) $ (296,315)
Beginning Balance, Shares at Dec. 31, 2021         38,560,854                  
Stock-based compensation 18,516               18,516          
Stock option exercises 80               80          
Stock option exercises, Shares         15,364                  
Issuance of common stock, pre-funded warrants and common warrants, net of issuance costs, Value       $ 122,488       $ 9       $ 122,479    
Issuance of common stock, pre-funded warrants and common warrants, net of issuance cost, Shares               9,013,834            
Issuance of common stock per Employee Stock Purchase Plan purchase 340               340          
Issuance of common stock per Employee Stock Purchase Plan purchase, Shares         121,126                  
Restricted stock vested in the period         11,817                  
Other comprehensive gain (loss) (192)                       (192)  
Net loss (141,947)                         (141,947)
Ending Balance, Values at Dec. 31, 2022 231,194       $ 48       669,780       (372) (438,262)
Ending Balance, Shares at Dec. 31, 2022         47,722,995                  
Stock-based compensation 18,183               18,183          
Stock option exercises $ 145               145          
Stock option exercises, Shares 76,888       76,888                  
Exercise of pre-funded warrants, Value         $ 3       (3)          
Exercise of pre-funded warrants, Shares         2,582,557                  
Issuance of common stock, pre-funded warrants and common warrants, net of issuance costs, Value   $ 17,470 $ 117,002     $ 2 $ 25     $ 17,468 $ 116,977      
Issuance of common stock, pre-funded warrants and common warrants, net of issuance cost, Shares           2,646,458 25,035,000              
Issuance of common stock per Employee Stock Purchase Plan purchase $ 479               479          
Issuance of common stock per Employee Stock Purchase Plan purchase, Shares         133,105                  
Restricted stock vested in the period         172,096                  
Other comprehensive gain (loss) 320                       320  
Net loss (134,237)                         (134,237)
Ending Balance, Values at Dec. 31, 2023 $ 250,556       $ 78       $ 823,029       $ (52) $ (572,499)
Ending Balance, Shares at Dec. 31, 2023         78,369,099