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Income Taxes - Deferred Tax Assets and Liabilities (Detail) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
--- | --- | ---
Income Tax Disclosure [Abstract] |  |
Net operating loss carryforwards | $ 94,198 | $ 70,996
Research and development credits | 29,095 | 16,070
Other intangibles | 5 | 3
Accruals and reserves | 1,116 | 1,074
Stock-based compensation | 5,599 | 5,185
Capitalized research and development | 49,837 | 36,568
Lease liabilities | 6,087 | 6,610
Total gross deferred tax assets | 185,937 | 136,506
Less: valuation allowance | (180,958) | (130,939)
Total deferred tax assets, net | 4,979 | 5,567
Fixed assets | (1,469) | (1,771)
Right-of-use assets | (3,510) | (3,796)
Total gross deferred tax liabilities | (4,979) | (5,567)
Net deferred tax assets | $ 0 | $ 0

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