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Condensed Consolidated Statements of Stockholders' Equity - USD ($) $ in Thousands | Total | Common Stock [Member] | Additional Paid-in Capital [Member] | Accumulated Other Comprehensive Income (Loss) [Member] | Accumulated Deficit [Member]
--- | --- | --- | --- | --- | ---
Beginning Balance, Values at Dec. 31, 2023 | $ 250,556 | $ 78 | $ 823,029 | $ (52) | $ (572,499)
Beginning Balance, Shares at Dec. 31, 2023 |  | 78,369,099 |  |  |
Exercise of stock options | 217 |  | 217 |  |
Exercise of stock options, Shares |  | 105,526 |  |  |
Issuance of common stock, net of issuance costs, Value | 32,198 | $ 7 | 32,191 |  |
Issuance of common stock, net of issuance costs, Shares |  | 6,639,348 |  |  |
Exercise of pre-funded warrants, Value |  | $ 5 | (5) |  |
Exercise of pre-funded warrants, Shares |  | 5,243,400 |  |  |
Restricted stock vested in the period |  | 124,695 |  |  |
Stock-based compensation | 4,660 |  | 4,660 |  |
Other comprehensive loss | (50) |  |  | (50) |
Net loss | (25,176) |  |  |  | (25,176)
Ending Balance, Values at Mar. 31, 2024 | 262,405 | $ 90 | 860,092 | (102) | (597,675)
Ending Balance, Shares at Mar. 31, 2024 |  | 90,482,068 |  |  |
Beginning Balance, Values at Dec. 31, 2023 | 250,556 | $ 78 | 823,029 | (52) | (572,499)
Beginning Balance, Shares at Dec. 31, 2023 |  | 78,369,099 |  |  |
Net loss | (54,786) |  |  |  |
Ending Balance, Values at Jun. 30, 2024 | 361,079 | $ 106 | 988,347 | (89) | (627,285)
Ending Balance, Shares at Jun. 30, 2024 |  | 105,539,683 |  |  |
Beginning Balance, Values at Mar. 31, 2024 | 262,405 | $ 90 | 860,092 | (102) | (597,675)
Beginning Balance, Shares at Mar. 31, 2024 |  | 90,482,068 |  |  |
Exercise of stock options | 171 |  | 171 |  |
Exercise of stock options, Shares |  | 35,914 |  |  |
Issuance of common stock per Employee Stock Purchase Plan purchase, Value | 215 | $ 1 | 214 |  |
Issuance of common stock per Employee Stock Purchase Plan purchase, Shares |  | 98,534 |  |  |
Issuance of common stock, net of issuance costs, Value | 6,126 | $ 1 | 6,125 |  |
Issuance of common stock, net of issuance costs, Shares |  | 936,719 |  |  |
Issuance of common stock and pre-funded warrants, net of issuance costs, Value | 116,817 | $ 13 | 116,804 |  |
Issuance of common stock and pre-funded warrants, net of issuance costs, Shares |  | 13,001,120 |  |  |
Exercise of pre-funded warrants, Value |  | $ 1 | (1) |  |
Exercise of pre-funded warrants, Shares |  | 965,427 |  |  |
Exercise of common warrants, Shares |  | 19,901 |  |  |
Stock-based compensation | 4,942 |  | 4,942 |  |
Other comprehensive loss | 13 |  |  | 13 |
Net loss | (29,610) |  |  |  | (29,610)
Ending Balance, Values at Jun. 30, 2024 | 361,079 | $ 106 | 988,347 | (89) | (627,285)
Ending Balance, Shares at Jun. 30, 2024 |  | 105,539,683 |  |  |
Beginning Balance, Values at Dec. 31, 2024 | 293,105 | $ 109 | 1,003,685 | 10 | (710,699)
Beginning Balance, Shares at Dec. 31, 2024 |  | 109,381,556 |  |  |
Exercise of stock options | 62 |  | 62 |  |
Exercise of stock options, Shares |  | 43,113 |  |  |
Restricted stock vested in the period |  | 289,735 |  |  |
Stock-based compensation | 5,078 |  | 5,078 |  |
Other comprehensive loss | (101) |  |  | (101) |
Net loss | (54,356) |  |  |  | (54,356)
Ending Balance, Values at Mar. 31, 2025 | 243,788 | $ 109 | 1,008,825 | (91) | (765,055)
Ending Balance, Shares at Mar. 31, 2025 |  | 109,714,404 |  |  |
Beginning Balance, Values at Dec. 31, 2024 | $ 293,105 | $ 109 | 1,003,685 | 10 | (710,699)
Beginning Balance, Shares at Dec. 31, 2024 |  | 109,381,556 |  |  |
Exercise of stock options, Shares | 43,113 |  |  |  |
Net loss | $ (103,512) |  |  |  |
Ending Balance, Values at Jun. 30, 2025 | 199,017 | $ 110 | 1,013,211 | (93) | (814,211)
Ending Balance, Shares at Jun. 30, 2025 |  | 109,832,147 |  |  |
Beginning Balance, Values at Mar. 31, 2025 | 243,788 | $ 109 | 1,008,825 | (91) | (765,055)
Beginning Balance, Shares at Mar. 31, 2025 |  | 109,714,404 |  |  |
Issuance of common stock per Employee Stock Purchase Plan purchase, Value | 182 | $ 1 | 181 |  |
Issuance of common stock per Employee Stock Purchase Plan purchase, Shares |  | 117,743 |  |  |
Stock-based compensation | 4,205 |  | 4,205 |  |
Other comprehensive loss | (2) |  |  | (2) |
Net loss | (49,156) |  |  |  | (49,156)
Ending Balance, Values at Jun. 30, 2025 | $ 199,017 | $ 110 | $ 1,013,211 | $ (93) | $ (814,211)
Ending Balance, Shares at Jun. 30, 2025 |  | 109,832,147 |  |  |

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