    <SEC-DOCUMENT>0001140361-26-017091-index.html : 20260427
    <SEC-HEADER>0001140361-26-017091.hdr.sgml : 20260427
    <ACCEPTANCE-DATETIME>20260427161032
    ACCESSION NUMBER:		0001140361-26-017091
    CONFORMED SUBMISSION TYPE:	ARS
    PUBLIC DOCUMENT COUNT:		1
    CONFORMED PERIOD OF REPORT:	20251231
    FILED AS OF DATE:		20260427
    DATE AS OF CHANGE:		20260427
    EFFECTIVENESS DATE:		20260427

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			Annexon, Inc.
    		CENTRAL INDEX KEY:			0001528115
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		ORGANIZATION NAME:           	03 Life Sciences
    		EIN:				275414423
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		ARS
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-39402
    		FILM NUMBER:		26900999

    	BUSINESS ADDRESS:
    		STREET 1:		1400 SIERRA POINT PARKWAY
    		STREET 2:		BLDG C, SUITE 200
    		CITY:			BRISBANE
    		STATE:			CA
    		ZIP:			94005
    		BUSINESS PHONE:		(650) 822-5500

    	MAIL ADDRESS:
    		STREET 1:		1400 SIERRA POINT PARKWAY
    		STREET 2:		BLDG C, SUITE 200
    		CITY:			BRISBANE
    		STATE:			CA
    		ZIP:			94005
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>ARS
    <SEQUENCE>1
    <FILENAME>ny20063060x4_ars.pdf
    <DESCRIPTION>ARS
    <TEXT>
    Document 1 - file: ny20063060x4_ars.pdf

    </DOCUMENT>
    </SEC-DOCUMENT>