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Schedule of Outstanding Warrants to Purchase Common Stock (Details) - USD ($)
 12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Outstanding Warrants    
Warrants Outstanding, Beginning Balance 50,417 260,727
Weighted Average Exercise Price, Beginning Balance $ 37.50 $ 36.00
Weighted Average Life of Outstanding Warrants in Months, Beginning Balance 6 months 9 months
Aggregate Intrinsic Value, Beginning Balance $ 0 $ 0
Warrants, issued 222,719
Weighted Average Exercise Price, Issued $ 9.59
Aggregate Intrinsic Value, Issued
Warrants, Exercised
Weighted Average Exercise Price, Exercised
Aggregate Intrinsic Value, Exercised
Warrants, Expired (50,417) (210,310)
Weighted Average Exercise Price, Expired $ 37.50 $ (34.50)
Aggregate Intrinsic Value, Expired $ 0 $ 0
Weighted Average Life of Outstanding Warrants in Months, Issued 36 months  
Warrants Outstanding, Ending Balance 227,719 50,417
Weighted Average Exercise Price, Ending Balance $ 9.59 $ 37.50
Weighted Average Life of Outstanding Warrants in Months, Ending Balance 33 months  
Aggregate Intrinsic Value, Ending Balance $ 0 $ 0