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LICENSE AGREEMENTS (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Apr. 28, 2021
USD ($)
Mar. 31, 2022
USD ($)
Jun. 30, 2023
USD ($)
Mar. 31, 2023
USD ($)
Mar. 31, 2022
USD ($)
Jun. 30, 2023
USD ($)
Jun. 30, 2023
EUR (€)
Jun. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
Jan. 24, 2022
USD ($)
LICENSE AGREEMENTS                    
Milestone payment received           $ 5,095,837   $ 30,000,000    
Revenue     $ 3,917,467     6,904,163        
Deferred revenue, current     29,312,439     29,312,439     $ 17,980,599  
Deferred revenue, net of current     3,231,929     3,231,929     $ 9,467,932  
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                    
LICENSE AGREEMENTS                    
Potential milestone payments                   $ 705,000,000.0
Upfront Payment         $ 30,000,000.0          
Deferred revenue liability   $ 30,000,000.0 20,500,000   30,000,000.0 20,500,000        
Revenue     3,900,000     6,900,000        
Deferred revenue, current     17,300,000     17,300,000        
Deferred revenue, net of current     $ 3,200,000     $ 3,200,000        
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2023-07-01                    
LICENSE AGREEMENTS                    
Revenue, Remaining Performance Obligation, Percentage     84.00%     84.00%        
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period     6 months     6 months        
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2024-07-01                    
LICENSE AGREEMENTS                    
Revenue, Remaining Performance Obligation, Percentage     84.00%     84.00%        
Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Period     12 months     12 months        
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan                    
LICENSE AGREEMENTS                    
Potential milestone payments       $ 89,000,000            
Upfront Payment       12,000,000.0            
Milestone payment received       $ 12,000,000.0            
Deferred revenue liability     $ 12,000,000.0     $ 12,000,000.0        
Deferred revenue, current     12,000,000.0     $ 12,000,000.0        
Rome License Agreement                    
LICENSE AGREEMENTS                    
Notice period           90 days 90 days      
JHU License Agreement                    
LICENSE AGREEMENTS                    
Notice period           60 days 60 days      
Milestone payments to be made upon completion of certain phases   500,000     $ 500,000          
Threshold period to cure breach           30 days 30 days      
CSMC License Agreement                    
LICENSE AGREEMENTS                    
Notice period           90 days 90 days      
Exosomes License Agreement                    
LICENSE AGREEMENTS                    
Notice period 90 days         90 days 90 days      
Upfront Payment $ 10,000                  
Minimum | Rome License Agreement                    
LICENSE AGREEMENTS                    
Minimum annual royalty payments | €             € 20,000      
Maximum | JHU License Agreement                    
LICENSE AGREEMENTS                    
Potential milestone payments     $ 1,850,000     $ 1,850,000        
Completion Of Phase Two Due | JHU License Agreement                    
LICENSE AGREEMENTS                    
Milestones paid   $ 250,000                
Patent rights | JHU License Agreement                    
LICENSE AGREEMENTS                    
Agreement effective period           20 years 20 years      
Patent rights | Exosomes License Agreement                    
LICENSE AGREEMENTS                    
Agreement effective period 20 years                  
Particular Patent or Application or Any Particular Licensed Product | Exosomes License Agreement                    
LICENSE AGREEMENTS                    
Notice period 60 days                  
Non Payment of Royalties | CSMC License Agreement                    
LICENSE AGREEMENTS                    
Agreement termination period           30 days 30 days      
Non Payment of Royalties | Exosomes License Agreement                    
LICENSE AGREEMENTS                    
Threshold period to cure breach           30 days 30 days      
CSMC Agreement Compliance | CSMC License Agreement                    
LICENSE AGREEMENTS                    
Agreement termination period           90 days 90 days      
CSMC Agreement Compliance | Exosomes License Agreement                    
LICENSE AGREEMENTS                    
Threshold period to cure breach           90 days 90 days      
Material Breach Has Not Been Cured | CSMC License Agreement                    
LICENSE AGREEMENTS                    
Agreement termination period           90 days 90 days      
Material Breach Has Not Been Cured | Exosomes License Agreement                    
LICENSE AGREEMENTS                    
Threshold period to cure breach           90 days 90 days      
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement                    
LICENSE AGREEMENTS                    
Agreement termination period           90 days 90 days      
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement                    
LICENSE AGREEMENTS                    
Threshold period to cure breach 60 days         90 days 90 days