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ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Additional Information (Details) - USD ($) |  | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Oct. 03, 2023 | Mar. 31, 2024 | Mar. 31, 2023 | Dec. 31, 2023 | Dec. 31, 2022 | Dec. 31, 2021 | Dec. 31, 2020
Accounting Policies [Line Items] |  |  |  |  |  |  |
Cash, cash equivalents, and marketable securities |  |  |  | $ 39,500,000 | $ 41,400,000 |  |
Milestone payment received |  |  | $ 12,000,000.0 | (3,178,066) | 27,448,531 |  |
Gross proceeds from sale of common stock |  |  |  | 25,515,349 | 4,803,534 |  |
Revenue recognized under "ERC" |  |  |  | 191,463 |  | $ 191,199 |
Receivables under "ERC" |  |  |  | 366,551 |  | $ 738,778 | $ 738,778
Depreciation |  |  |  | 1,068,882 | 533,131 |  |
Grant income |  |  |  | 0 | 0 |  |
Tax credit carryforward amount |  |  |  | 50,700,000 |  |  |
Research and development |  |  |  | 36,448,039 | 21,816,949 |  |
Comprehensive loss |  |  |  | 22,156,973 | 28,914,288 |  |
Long-lived assets impairment |  |  |  | 0 | 0 |  |
Interest and penalties related to unrecognized tax benefits |  |  |  | 0 | $ 0 |  |
Registered Direct Offering [Member] |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Gross proceeds from sale of common stock | $ 23,000,000.0 |  |  |  |  |  |
Domestic Country |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Operating loss carryforwards |  |  |  | $ 106,900,000 |  |  |
Operating loss carryforwards expiration year |  |  |  | 2027 |  |  |
Tax credit carryforward limitations on use |  |  |  | The post December 31, 2017 net operating losses generated of approximately $56.2 million will carryforward indefinitely, but may be subject to an 80% limitation upon utilization. |  |  |
Operating loss carry forwards indefinitely |  |  |  | $ 56,200,000 |  |  |
State and Local Jurisdiction |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Operating loss carryforwards |  |  |  | $ 147,300,000 |  |  |
Operating loss carryforwards expiration year |  |  |  | 2028 |  |  |
General Business |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Tax credit carryforward amount |  |  |  | $ 3,700,000 |  |  |
Operating loss carryforwards expiration year |  |  |  | 2035 |  |  |
Research Tax Credit Carryforward |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Tax credit carryforward amount |  |  |  | $ 6,200,000 |  |  |
Tax credit carry forwards expiration Year |  |  |  | 2027 |  |  |
Research Tax Credit Carryforward | California |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Tax credit carryforward amount |  |  |  | $ 2,200,000 |  |  |
Warrant |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Antidilutive securities |  |  |  | 13,268,807 | 5,882,621 |  |
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Milestone payment received |  | $ 10,000,000.0 |  |  |  |  |
Minimum |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Estimated useful lives (in years) |  |  |  | 5 years |  |  |
Maximum |  |  |  |  |  |  |
Accounting Policies [Line Items] |  |  |  |  |  |  |
Estimated useful lives (in years) |  |  |  | 7 years |  |  |

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 260 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 1 -Subparagraph (c) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482662/260-10-50-1 + Details
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