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v3.24.1.1.u2

LICENSE AND DISTRIBUTION AGREEMENTS (Details) | 3 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | ---
Mar. 31, 2024 USD ($) | Mar. 31, 2024 EUR (€) | Mar. 31, 2023 USD ($) | Mar. 31, 2022 USD ($) | Dec. 31, 2022 USD ($) | Jan. 31, 2024 USD ($) | Dec. 31, 2023 USD ($) | Jan. 24, 2022 USD ($)
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Revenue | $ 4,906,877 |  | $ 2,986,696 |  |  |  |  |
Deferred revenue, current | 19,363,589 |  |  |  |  |  | $ 24,270,465 |
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Potential milestone payments | 90,000,000.0 |  |  |  |  |  |  |
Milestone payments to be made upon completion of certain phases | 10,000,000.0 |  |  |  |  |  |  |
Upfront payment | 30,000,000.0 |  |  | $ 30,000,000.0 |  |  |  |
Deferred revenue liability | 7,400,000 |  |  | $ 40,000,000.0 |  |  |  |
Revenue | 4,900,000 |  | 3,000,000.0 |  |  |  |  |
Deferred revenue, current | $ 7,400,000 |  |  |  |  |  |  |
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2024-04-01 |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Revenue, remaining performance obligation, expected timing of satisfaction, period | 12 months |  |  |  |  |  |  |
Revenue, Remaining Performance Obligation, Percentage | 100.00% |  |  |  |  |  |  |
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Potential milestone payments |  |  | 89,000,000.0 |  |  |  |  |
Milestone payments to be made upon completion of certain phases | $ 10,000,000.0 |  |  |  |  |  |  |
Upfront payment |  |  | $ 12,000,000.0 |  |  |  |  |
Deferred revenue liability | 12,000,000.0 |  |  |  |  |  |  |
Deferred revenue, current | $ 12,000,000.0 |  |  |  |  |  |  |
CSMC | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Deferred revenue liability |  |  |  |  |  | $ 40,000,000.0 |  |
Rome License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Notice period | 90 days | 90 days |  |  |  |  |  |
JHU License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Notice period | 60 days | 60 days |  |  |  |  |  |
Threshold period to cure breach | 30 days | 30 days |  |  |  |  |  |
CSMC License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Notice period | 90 days | 90 days |  |  |  |  |  |
Exosomes License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Notice period | 90 days | 90 days |  |  |  |  |  |
Minimum | Rome License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Minimum annual royalty payments | € |  | € 20,000 |  |  |  |  |  |
Maximum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Potential milestone payments |  |  |  |  |  |  |  | $ 605,000,000.0
Maximum | JHU License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Potential milestone payments | $ 1,850,000 |  |  |  |  |  |  |
Completion Of Phase Two Due | JHU License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Milestones paid |  |  |  |  | $ 250,000 |  |  |
Milestone payments to be made upon completion of certain phases |  |  |  |  | $ 500,000 |  |  |
Patent rights | JHU License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Agreement effective period | 20 years | 20 years |  |  |  |  |  |
Non Payment of Royalties | CSMC License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Agreement termination period | 30 days | 30 days |  |  |  |  |  |
Non Payment of Royalties | Exosomes License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Threshold period to cure breach | 30 days | 30 days |  |  |  |  |  |
CSMC Agreement Compliance | CSMC License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Agreement termination period | 90 days | 90 days |  |  |  |  |  |
CSMC Agreement Compliance | Exosomes License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Threshold period to cure breach | 90 days | 90 days |  |  |  |  |  |
Material Breach Has Not Been Cured | CSMC License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Agreement termination period | 90 days | 90 days |  |  |  |  |  |
Material Breach Has Not Been Cured | Exosomes License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Threshold period to cure breach | 90 days | 90 days |  |  |  |  |  |
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Agreement termination period | 90 days | 90 days |  |  |  |  |  |
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Threshold period to cure breach | 90 days | 90 days |  |  |  |  |  |
Overdue payment obligation | CSMC License Agreement | CSMC |  |  |  |  |  |  |  |
LICENSE AGREEMENTS |  |  |  |  |  |  |  |
Revenue | $ 10,000,000.0 |  |  |  |  |  |  |
Milestone payments, percentage claimed by CSMS | 10.00% |  |  |  |  |  |  |
Milestone payments, amount claimed by CSMS | $ 1,000,000.0 |  |  |  |  |  |  |

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