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LICENSE AND DISTRIBUTION AGREEMENTS (Details)
3 Months Ended 12 Months Ended
Mar. 31, 2024
USD ($)
Mar. 31, 2024
EUR (€)
Mar. 31, 2023
USD ($)
Mar. 31, 2022
USD ($)
Dec. 31, 2022
USD ($)
Jan. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Jan. 24, 2022
USD ($)
LICENSE AGREEMENTS                
Revenue $ 4,906,877   $ 2,986,696          
Deferred revenue, current 19,363,589           $ 24,270,465  
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                
LICENSE AGREEMENTS                
Potential milestone payments 90,000,000.0              
Milestone payments to be made upon completion of certain phases 10,000,000.0              
Upfront payment 30,000,000.0     $ 30,000,000.0        
Deferred revenue liability 7,400,000     $ 40,000,000.0        
Revenue 4,900,000   3,000,000.0          
Deferred revenue, current $ 7,400,000              
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date [Axis]: 2024-04-01                
LICENSE AGREEMENTS                
Revenue, remaining performance obligation, expected timing of satisfaction, period 12 months              
Revenue, Remaining Performance Obligation, Percentage 100.00%              
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan                
LICENSE AGREEMENTS                
Potential milestone payments     89,000,000.0          
Milestone payments to be made upon completion of certain phases $ 10,000,000.0              
Upfront payment     $ 12,000,000.0          
Deferred revenue liability 12,000,000.0              
Deferred revenue, current $ 12,000,000.0              
CSMC | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                
LICENSE AGREEMENTS                
Deferred revenue liability           $ 40,000,000.0    
Rome License Agreement                
LICENSE AGREEMENTS                
Notice period 90 days 90 days            
JHU License Agreement                
LICENSE AGREEMENTS                
Notice period 60 days 60 days            
Threshold period to cure breach 30 days 30 days            
CSMC License Agreement                
LICENSE AGREEMENTS                
Notice period 90 days 90 days            
Exosomes License Agreement                
LICENSE AGREEMENTS                
Notice period 90 days 90 days            
Minimum | Rome License Agreement                
LICENSE AGREEMENTS                
Minimum annual royalty payments | €   € 20,000            
Maximum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                
LICENSE AGREEMENTS                
Potential milestone payments               $ 605,000,000.0
Maximum | JHU License Agreement                
LICENSE AGREEMENTS                
Potential milestone payments $ 1,850,000              
Completion Of Phase Two Due | JHU License Agreement                
LICENSE AGREEMENTS                
Milestones paid         $ 250,000      
Milestone payments to be made upon completion of certain phases         $ 500,000      
Patent rights | JHU License Agreement                
LICENSE AGREEMENTS                
Agreement effective period 20 years 20 years            
Non Payment of Royalties | CSMC License Agreement                
LICENSE AGREEMENTS                
Agreement termination period 30 days 30 days            
Non Payment of Royalties | Exosomes License Agreement                
LICENSE AGREEMENTS                
Threshold period to cure breach 30 days 30 days            
CSMC Agreement Compliance | CSMC License Agreement                
LICENSE AGREEMENTS                
Agreement termination period 90 days 90 days            
CSMC Agreement Compliance | Exosomes License Agreement                
LICENSE AGREEMENTS                
Threshold period to cure breach 90 days 90 days            
Material Breach Has Not Been Cured | CSMC License Agreement                
LICENSE AGREEMENTS                
Agreement termination period 90 days 90 days            
Material Breach Has Not Been Cured | Exosomes License Agreement                
LICENSE AGREEMENTS                
Threshold period to cure breach 90 days 90 days            
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement                
LICENSE AGREEMENTS                
Agreement termination period 90 days 90 days            
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement                
LICENSE AGREEMENTS                
Threshold period to cure breach 90 days 90 days            
Overdue payment obligation | CSMC License Agreement | CSMC                
LICENSE AGREEMENTS                
Revenue $ 10,000,000.0              
Milestone payments, percentage claimed by CSMS 10.00%              
Milestone payments, amount claimed by CSMS $ 1,000,000.0