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ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES - Additional Information (Details) - USD ($)
 1 Months Ended 12 Months Ended
Jan. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2021
Dec. 31, 2020
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Accumulated deficit   $ 199,834,539 $ 159,367,353    
Cash, cash equivalents, and marketable securities   151,500,000      
Milestone payment received   (12,270,465) (3,178,066)    
Receivables under "ERC"   366,551 366,551 $ 738,778 $ 738,778
Revenue recognized under "ERC"     191,463 $ 191,199  
Long-lived assets impairment   0 0    
Grant income   0 0    
Tax credit carryforward amount   40,900,000      
Research and development   49,968,585 36,448,039    
Comprehensive loss   (39,676,044) (22,156,973)    
Net unrealized gain on marketable securities   791,142 $ 130,569    
Subsequent event          
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Revenue recognized under "ERC" $ 190,582        
Domestic Country          
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Operating loss carryforwards   $ 97,100,000      
Operating loss carryforwards expiration year   2032      
Tax credit carryforward limitations on use   The post December 31, 2017 net operating losses generated of approximately $56.3 million will carryforward indefinitely, but may be subject to an 80% limitation upon utilization.      
Operating loss carry forwards indefinitely   $ 56,300,000      
State and Local Jurisdiction          
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Operating loss carryforwards   $ 176,800,000      
Operating loss carryforwards expiration year   2028      
General Business          
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Tax credit carryforward amount   $ 11,800,000      
Operating loss carryforwards expiration year   2035      
Research Tax Credit Carryforward          
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Tax credit carryforward amount   $ 6,300,000      
Tax credit carry forwards expiration Year   2027      
Research Tax Credit Carryforward | California          
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Tax credit carryforward amount   $ 2,100,000      
Warrant          
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Antidilutive securities   15,666,804 13,268,807    
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan | Investor          
ORGANIZATION AND SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES          
Accounts receivable   $ 10,000,000 $ 10,000,000