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LICENSE AND DISTRIBUTION AGREEMENTS (Details)		1 Months Ended	3 Months Ended	12 Months Ended
	Sep. 16, 2024 USD ($)	Dec. 31, 2024 USD ($)	Mar. 31, 2023 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2024 EUR (€)	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Jan. 24, 2022 USD ($)
LICENSE AGREEMENTS
Revenue				$ 22,270,465		$ 25,178,066
Deferred revenue, current		$ 12,000,000		12,000,000		24,270,465
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Potential milestone payments		80,000,000		80,000,000
Milestone payments to be made upon completion of certain phases		10,000,000		10,000,000		10,000,000
Upfront payment							$ 30,000,000
Revenue				22,300,000		25,200,000
Deferred revenue, current						$ 12,300,000
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan
LICENSE AGREEMENTS
Potential milestone payments			$ 89,000,000
Upfront payment			$ 12,000,000
Deferred revenue liability		12,000,000		12,000,000
Deferred revenue, current		12,000,000		$ 12,000,000
Binding Term Sheet With Nippon Shinyaku Co Limited Europe
LICENSE AGREEMENTS
Upfront payment	$ 20,000,000
Potential additional development and sales-based milestone payments	$ 715,000,000
Rome License Agreement
LICENSE AGREEMENTS
Notice period				90 days	90 days
JHU License Agreement
LICENSE AGREEMENTS
Notice period				60 days	60 days
Threshold period to cure breach				30 days	30 days
CSMC License Agreement
LICENSE AGREEMENTS
Notice period				90 days	90 days
Exosomes License Agreement
LICENSE AGREEMENTS
Notice period				90 days	90 days
Minimum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Share of product revenue (in percent)								30.00%
Minimum | Rome License Agreement
LICENSE AGREEMENTS
Minimum annual royalty payments | €					€ 20,000
Maximum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Potential milestone payments								$ 605,000,000
Share of product revenue (in percent)								50.00%
Maximum | JHU License Agreement
LICENSE AGREEMENTS
Potential milestone payments		1,850,000		$ 1,850,000
Completion Of Phase Three | JHU License Agreement
LICENSE AGREEMENTS
Milestone payments to be made upon completion of certain phases							500,000
Obtention of FDA Approval | JHU License Agreement
LICENSE AGREEMENTS
Milestone payments to be made upon completion of certain phases							1,000,000
Completion Of Phase Two Due | JHU License Agreement
LICENSE AGREEMENTS
Milestones paid							$ 250,000
First Milestone Payment
LICENSE AGREEMENTS
Milestone payments to be made upon completion of certain phases		10,000,000		10,000,000
First Milestone Payment | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Milestone payments to be made upon completion of certain phases		10,000,000		10,000,000
Upfront payment				30,000,000
First Milestone Payment | CSMC | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Recognized as revenue				40,000,000
Deferred revenue liability		40,000,000		40,000,000
Second Milestone Payment | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Milestones paid		10,000,000
Upfront payment				30,000,000
Deferred revenue, current		0		0
Second Milestone Payment | CSMC | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Deferred revenue liability		50,000,000		50,000,000
Development Milestone Payment, One | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Milestone payments to be made upon completion of certain phases		10,000,000		10,000,000
Development Milestone Payment, Two | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States
LICENSE AGREEMENTS
Milestone payments to be made upon completion of certain phases		$ 10,000,000		$ 10,000,000
Patent rights | JHU License Agreement
LICENSE AGREEMENTS
Agreement effective period				20 years	20 years
Non Payment of Royalties | CSMC License Agreement
LICENSE AGREEMENTS
Agreement termination period				30 days	30 days
Non Payment of Royalties | Exosomes License Agreement
LICENSE AGREEMENTS
Threshold period to cure breach				30 days	30 days
CSMC Agreement Compliance | CSMC License Agreement
LICENSE AGREEMENTS
Agreement termination period				90 days	90 days
CSMC Agreement Compliance | Exosomes License Agreement
LICENSE AGREEMENTS
Threshold period to cure breach				90 days	90 days
Material Breach Has Not Been Cured | CSMC License Agreement
LICENSE AGREEMENTS
Agreement termination period				90 days	90 days
Material Breach Has Not Been Cured | Exosomes License Agreement
LICENSE AGREEMENTS
Threshold period to cure breach				90 days	90 days
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement
LICENSE AGREEMENTS
Agreement termination period				90 days	90 days
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement
LICENSE AGREEMENTS
Threshold period to cure breach				90 days	90 days

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