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LICENSE AND DISTRIBUTION AGREEMENTS (Details)
1 Months Ended 3 Months Ended 12 Months Ended
Sep. 16, 2024
USD ($)
Dec. 31, 2024
USD ($)
Mar. 31, 2022
USD ($)
Mar. 31, 2025
EUR (€)
Mar. 31, 2024
USD ($)
Mar. 31, 2023
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Mar. 31, 2025
USD ($)
Jan. 24, 2022
USD ($)
LICENSE AGREEMENTS                      
Revenue         $ 4,906,877            
Deferred revenue, current   $ 12,000,000         $ 12,000,000     $ 12,000,000  
Receivables   10,368,489         10,368,489     59,834  
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                      
LICENSE AGREEMENTS                      
Potential milestone payments                     $ 80,000,000
Milestones paid   10,000,000           $ 10,000,000      
Upfront payment                 $ 30,000,000    
Deferred revenue liability   0         0     0  
Revenue         $ 4,900,000   40,000,000        
Receivables   $ 10,000,000         10,000,000        
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan                      
LICENSE AGREEMENTS                      
Potential milestone payments                   89,000,000  
Upfront payment           $ 12,000,000          
Deferred revenue liability                   12,000,000  
Deferred revenue, current                   12,000,000  
Binding Term Sheet With Nippon Shinyaku Co Limited Europe                      
LICENSE AGREEMENTS                      
Upfront payment $ 20,000,000                    
Potential additional development and sales-based milestone payments $ 715,000,000                    
CSMC | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                      
LICENSE AGREEMENTS                      
Deferred revenue liability                   40,000,000  
Rome License Agreement                      
LICENSE AGREEMENTS                      
Notice period       90 days              
JHU License Agreement                      
LICENSE AGREEMENTS                      
Notice period       60 days              
Threshold period to cure breach       30 days              
CSMC License Agreement                      
LICENSE AGREEMENTS                      
Notice period       90 days              
Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Notice period       90 days              
Minimum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                      
LICENSE AGREEMENTS                      
Share of product revenue (in percent)                     30.00%
Minimum | Rome License Agreement                      
LICENSE AGREEMENTS                      
Minimum annual royalty payments | €       € 20,000              
Maximum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                      
LICENSE AGREEMENTS                      
Share of product revenue (in percent)                     50.00%
Potential additional development and sales-based milestone payments                     $ 605,000,000
Maximum | JHU License Agreement                      
LICENSE AGREEMENTS                      
Potential milestone payments                   1,850,000  
Obtention of FDA Approval | JHU License Agreement                      
LICENSE AGREEMENTS                      
Milestone payments to be made upon completion of certain phases                   1,000,000  
Completion Of Phase Two Due | JHU License Agreement                      
LICENSE AGREEMENTS                      
Milestones paid     $ 250,000                
Milestone payments to be made upon completion of certain phases                   $ 500,000  
Second Milestone Payment | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                      
LICENSE AGREEMENTS                      
Revenue             $ 10,000,000        
Patent rights | JHU License Agreement                      
LICENSE AGREEMENTS                      
Agreement effective period       20 years              
Non Payment of Royalties | CSMC License Agreement                      
LICENSE AGREEMENTS                      
Agreement termination period       30 days              
Non Payment of Royalties | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Threshold period to cure breach       30 days              
CSMC Agreement Compliance | CSMC License Agreement                      
LICENSE AGREEMENTS                      
Agreement termination period       90 days              
CSMC Agreement Compliance | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Threshold period to cure breach       90 days              
Material Breach Has Not Been Cured | CSMC License Agreement                      
LICENSE AGREEMENTS                      
Agreement termination period       90 days              
Material Breach Has Not Been Cured | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Threshold period to cure breach       90 days              
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement                      
LICENSE AGREEMENTS                      
Agreement termination period       90 days              
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement                      
LICENSE AGREEMENTS                      
Threshold period to cure breach       90 days