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LICENSE AND DISTRIBUTION AGREEMENTS (Details)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 16, 2024
USD ($)
Dec. 31, 2024
USD ($)
Sep. 30, 2025
USD ($)
Sep. 30, 2024
USD ($)
Mar. 31, 2023
USD ($)
Sep. 30, 2025
USD ($)
Sep. 30, 2025
EUR (€)
Sep. 30, 2024
USD ($)
Dec. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
Dec. 31, 2022
USD ($)
Jan. 24, 2022
USD ($)
LICENSE AGREEMENTS                        
Revenue       $ 2,261,642       $ 11,139,956        
Deferred revenue, current   $ 12,000,000 $ 12,000,000     $ 12,000,000     $ 12,000,000      
Receivables   10,368,489 59,167     59,167     10,368,489      
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                        
LICENSE AGREEMENTS                        
Potential milestone payments                       $ 80,000,000
Milestones paid   10,000,000               $ 10,000,000    
Upfront payment                     $ 30,000,000  
Deferred revenue liability   0 0     0     0      
Revenue     0 $ 2,300,000   0   $ 11,100,000 40,000,000      
Receivables   $ 10,000,000             10,000,000      
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan                        
LICENSE AGREEMENTS                        
Potential milestone payments     89,000,000     89,000,000            
Upfront payment         $ 12,000,000              
Deferred revenue liability     12,000,000     12,000,000            
Deferred revenue, current     12,000,000     12,000,000            
Binding Term Sheet With Nippon Shinyaku Co Limited Europe                        
LICENSE AGREEMENTS                        
Upfront payment $ 20,000,000                      
Potential additional development and sales-based milestone payments $ 715,000,000                      
CSMC | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                        
LICENSE AGREEMENTS                        
Deferred revenue liability     40,000,000     $ 40,000,000            
Rome License Agreement                        
LICENSE AGREEMENTS                        
Notice period           90 days 90 days          
JHU License Agreement                        
LICENSE AGREEMENTS                        
Notice period           60 days 60 days          
Threshold period to cure breach           30 days 30 days          
CSMC License Agreement                        
LICENSE AGREEMENTS                        
Notice period           90 days 90 days          
Exosomes License Agreement                        
LICENSE AGREEMENTS                        
Notice period           90 days 90 days          
Minimum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                        
LICENSE AGREEMENTS                        
Share of product revenue (in percent)                       30.00%
Minimum | Rome License Agreement                        
LICENSE AGREEMENTS                        
Minimum annual royalty payments | €             € 20,000          
Maximum | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                        
LICENSE AGREEMENTS                        
Share of product revenue (in percent)                       50.00%
Potential additional development and sales-based milestone payments                       $ 605,000,000
Maximum | JHU License Agreement                        
LICENSE AGREEMENTS                        
Potential milestone payments     1,850,000     $ 1,850,000            
Obtention of FDA Approval | JHU License Agreement                        
LICENSE AGREEMENTS                        
Milestone payments to be made upon completion of certain phases     1,000,000     1,000,000            
Completion Of Phase Two Due | JHU License Agreement                        
LICENSE AGREEMENTS                        
Milestone payments to be made upon completion of certain phases     $ 500,000     $ 500,000            
Second Milestone Payment | Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States                        
LICENSE AGREEMENTS                        
Revenue                 $ 10,000,000      
Patent rights | JHU License Agreement                        
LICENSE AGREEMENTS                        
Agreement effective period           20 years 20 years          
Non Payment of Royalties | CSMC License Agreement                        
LICENSE AGREEMENTS                        
Agreement termination period           30 days 30 days          
Non Payment of Royalties | Exosomes License Agreement                        
LICENSE AGREEMENTS                        
Threshold period to cure breach           30 days 30 days          
CSMC Agreement Compliance | CSMC License Agreement                        
LICENSE AGREEMENTS                        
Agreement termination period           90 days 90 days          
CSMC Agreement Compliance | Exosomes License Agreement                        
LICENSE AGREEMENTS                        
Threshold period to cure breach           90 days 90 days          
Material Breach Has Not Been Cured | CSMC License Agreement                        
LICENSE AGREEMENTS                        
Agreement termination period           90 days 90 days          
Material Breach Has Not Been Cured | Exosomes License Agreement                        
LICENSE AGREEMENTS                        
Threshold period to cure breach           90 days 90 days          
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement                        
LICENSE AGREEMENTS                        
Agreement termination period           90 days 90 days          
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement                        
LICENSE AGREEMENTS                        
Threshold period to cure breach           90 days 90 days