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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) | 3 Months Ended
--- | ---
Mar. 31, 2026 | Mar. 31, 2025
Cash flows from operating activities: |  |
Net loss | $ (33,941,345) | $ (24,391,594)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Depreciation and amortization | 534,670 | 405,450
Stock-based compensation | 5,918,055 | 5,481,938
Restricted stock awards granted |  | 257,461
Amortization/accretion of note premiums/discounts | (358,625) |
Changes in lease liabilities | 641,285 | (16,844)
Other | (6,591) | 150,673
Changes in operating assets and liabilities: |  |
Receivables | 59,167 | 10,308,655
Prepaid expenses and other assets | 979,776 | 55,473
Accounts payable and accrued expenses | (3,081,283) | 1,315,268
Net cash used in operating activities | (29,254,891) | (6,433,520)
Cash flows from investing activities: |  |
Purchase of marketable securities | (174,893,062) | (18,181,600)
Proceeds from sales and maturities of marketable securities | 30,998,448 | 43,212,559
Purchases of property and equipment | (5,121,709) | (896,007)
Payments for leasehold improvements | (921,752) | (244,279)
Payments for construction in progress | (4,703,521) |
Net cash provided by (used in) investing activities | (154,641,596) | 23,890,673
Cash flows from financing activities: |  |
Proceeds from exercise of stock options | 1,470,659 | 50,354
Net cash provided by financing activities | 1,470,659 | 50,354
Net increase (decrease) in cash and cash equivalents | (182,425,828) | 17,507,507
Cash and cash equivalents balance at beginning of period | 287,847,312 | 11,286,996
Cash and cash equivalents balance at end of period | $ 105,421,484 | $ 28,794,503

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