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v3.26.1

COLLABORATIONS, LICENSES AND REVENUE (Details) | 1 Months Ended | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | ---
Apr. 30, 2026 USD ($) | Mar. 31, 2026 USD ($) | Mar. 31, 2026 EUR (€) | Mar. 31, 2025 USD ($) | Dec. 31, 2023 USD ($) | Dec. 31, 2025 USD ($)
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Deferred revenue, current |  | $ 12,000,000 |  |  |  | $ 12,000,000
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, United States |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Deferred revenue liability |  | 0 |  |  |  | 0
Revenue |  | 0 |  | $ 0 |  |
Accounts receivable |  | 0 |  |  |  | 0
Commercialization and Distribution Agreement with Nippon Shinyaku Co, Limited, Japan |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Potential milestone payments |  |  |  |  | $ 89,000,000 |
Upfront payment |  |  |  |  | $ 12,000,000 |
Deferred revenue liability |  | 12,000,000 |  |  |  |
Deferred revenue, current |  | 12,000,000 |  |  |  |
Japan Distribution Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Deferred revenue liability |  | 12,000,000 |  |  |  | 12,000,000
Upfront for performance obligation |  | $ 0 |  |  |  | $ 0
JHU License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Threshold period to cure breach |  | 30 days | 30 days |  |  |
Notice period |  | 60 days | 60 days |  |  |
JHU License Agreement | Subsequent events |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Milestone payments accrued | $ 500,000 |  |  |  |  |
CSMC License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Notice period |  | 90 days | 90 days |  |  |
Exosomes License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Notice period |  | 90 days | 90 days |  |  |
Minimum | Rome License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Minimum annual royalty payments | € |  |  | € 20,000 |  |  |
Minimum | JHU License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Potential milestone payments |  | $ 1,850,000 |  |  |  |
Obtention of FDA Approval | JHU License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Milestone payments to be made upon completion of certain phases |  | $ 1,000,000 |  |  |  |
Patent rights | JHU License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Agreement effective period |  | 20 years | 20 years |  |  |
Non Payment of Royalties | CSMC License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Agreement termination period |  | 30 days | 30 days |  |  |
Non Payment of Royalties | Exosomes License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Threshold period to cure breach |  | 30 days | 30 days |  |  |
CSMC Agreement Compliance | CSMC License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Agreement termination period |  | 90 days | 90 days |  |  |
CSMC Agreement Compliance | Exosomes License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Threshold period to cure breach |  | 90 days | 90 days |  |  |
Material Breach Has Not Been Cured | CSMC License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Agreement termination period |  | 90 days | 90 days |  |  |
Material Breach Has Not Been Cured | Exosomes License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Threshold period to cure breach |  | 90 days | 90 days |  |  |
Fails To Cure Breach after Notice From CSMC | CSMC License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Agreement termination period |  | 90 days | 90 days |  |  |
Fails To Cure Breach after Notice From CSMC | Exosomes License Agreement |  |  |  |  |  |
COLLABORATIONS, LICENSES AND REVENUE |  |  |  |  |  |
Threshold period to cure breach |  | 90 days | 90 days |  |  |

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