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Stockholders' equity - Equity offerings (Details) - USD ($) $ / shares in Units, $ in Thousands | 1 Months Ended | 12 Months Ended
--- | --- | ---
Oct. 31, 2020 | Jun. 30, 2020 | Dec. 31, 2019 | Nov. 30, 2019 | Mar. 31, 2021 | Mar. 31, 2020
Class of Warrant or Right [Line Items] |  |  |  |  |  |
Net proceeds from issuance after deducting underwriting discounts, commissions and other offering expenses | $ 269,975 | $ 107,782 | $ 85,598 |  |  |
Underwriting discounts, commissions and other offering expenses |  |  |  |  | $ 100 | $ 355
Number of common stocks are exercisable from the November 2019 Pre-Funded Warrants and the June 2020 Pre-Funded Warrants |  |  |  |  | 5,284,238 |
Pre-Funded Warrants |  |  |  |  |  |
Class of Warrant or Right [Line Items] |  |  |  |  |  |
Issuance of pre-funded warrants (in shares) | 1,562,500 | 1,521,738 |  |  |  |
Public offering price | $ 39.9999 | $ 22.9999 |  | $ 13.6099 |  |
Variation between public offering prices of common stock and Pre-Funded Warrants | $ 0.0001 | $ 0.0001 |  | $ 0.0001 |  |
Maximum percentage of holding for exercise warrants | 9.99% | 9.99% |  | 9.99% |  |
Prior notice period to change percentage of holding | 61 days | 61 days |  |  |  |
Maximum percentage of increase (decrease) of holding for exercise warrants | 19.99% | 19.99% |  |  |  |
Underwriter rights |  |  |  |  |  |
Class of Warrant or Right [Line Items] |  |  |  |  |  |
Number of shares issued | 5,625,000 | 3,478,261 | 838,530 | 4,516,561 |  |
Issuance of pre-funded warrants (in shares) |  |  |  | 2,200,000 |  |
Public offering price | $ 40.00 | $ 23.00 |  | $ 13.61 |  |
Shares issued during period | 937,500 | 652,173 |  |  |  |
Underwriting discounts, commissions and other offering expenses | $ 17,525 |  |  |  |  |
November 2019 Underwriting Agreement |  |  |  |  |  |
Class of Warrant or Right [Line Items] |  |  |  |  |  |
Underwriting discounts, commissions and other offering expenses |  |  | $ 5,814 |  |  |
June 2020 Underwriting Agreement |  |  |  |  |  |
Class of Warrant or Right [Line Items] |  |  |  |  |  |
Underwriting discounts, commissions and other offering expenses |  | $ 7,217 |  |  |  |

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