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Nature of the business (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Sep. 30, 2022
Jun. 30, 2022
Sep. 30, 2021
Jun. 30, 2021
Sep. 30, 2022
Sep. 30, 2021
Mar. 31, 2022
Organization, Consolidation and Presentation of Financial Statements [Abstract]              
Net loss $ (43,102) $ (42,253) $ (29,355) $ (27,311) $ (85,355) $ (56,666)  
Accumulated deficit $ (396,559)       $ (396,559)   $ (311,204)