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Income Taxes (Tables)
12 Months Ended
Dec. 31, 2021
Income Tax Disclosure [Abstract]  
Schedule of Effective Income Tax Rate Reconciliation
A reconciliation of the statutory U.S. federal rate to the Company’s effective tax rate is as follows:
December 31,
2021
2020
Tax at federal statutory rate21.0 %21.0 %
State taxes, net of federal benefit4.0 %7.6 %
Research and development tax credit1.3 %2.4 %
Stock-based compensation(1.1)%(0.6)%
Nondeductible interest expense
(0.6)%(5.5)%
Warrant mark-to-market adjustment(3.0)%0.2 %
FIN 48 reserve(0.2)%(0.4)%
Change in valuation allowance(21.5)%(21.8)%
Other0.1 %(2.9)%
Total — %— %
Schedule of Deferred Tax Assets and Liabilities
The tax effects of temporary differences that give rise to significant components of the deferred tax asset are as follows (in thousands):
December 31,
2021
2020
Net operating loss carryforwards$35,754 $30,367 
Research and development credits11,121 10,327 
Fixed assets and inventory120 743 
Accruals and reserves1,600 1,409 
Interest expense carryforward2,616 1,228 
Other781 146 
51,992 44,220 
Valuation allowance(51,992)(44,220)
Net deferred tax assets$— $— 
Schedule of Unrecognized Tax Benefits Roll Forward
A reconciliation of the beginning and ending unrecognized tax benefit amount is as follows (in thousands):
Year Ended December 31,
2021
2020
Beginning balance$1,390 $1,280 
Increase in balance related to tax positions taken during the current year99 109 
Increase in balance related to tax positions taken during prior years— 
Ending balance$1,489 $1,390